Company’s Internal Revenue Service Uses in Certificate Clause

Certificate from Registration Rights Agreement

This REGISTRATION RIGHTS AGREEMENT (this Agreement), dated as of August 4, 2008, is by and between ACADIA PHARMACEUTICALS INC. (the Company) and KINGSBRIDGE CAPITAL LIMITED (the Investor).

Certificate. The Company will, at its expense, forthwith upon the request of any holder of Registrable Securities, deliver to such holder a certificate, signed by the Companys principal financial officer, stating (a) the Companys name, address and telephone number (including area code), (b) the Companys Internal Revenue Service identification number, (c) the Companys Commission file number, (d) the number of shares of each class of capital stock outstanding as shown by the most recent report or statement published by the Company, and (e) whether the Company has filed the reports required to be filed under the Exchange Act for a period of at least ninety (90) days prior to the date of such certificate and in addition has filed the most recent annual report required to be filed thereunder.

Certificate from Registration Rights Agreement

This REGISTRATION RIGHTS AGREEMENT (this Agreement), dated as of May 7, 2008, is by and between JAZZ PHARMACEUTICALS, INC. (the Company) and KINGSBRIDGE CAPITAL LIMITED (the Investor).

Certificate. The Company will, at its expense, forthwith upon the request of any holder of Registrable Securities, deliver to such holder a certificate, signed by the Companys principal financial officer, stating (a) the Companys name, address and telephone number (including area code), (b) the Companys Internal Revenue Service identification number, (c) the Companys Commission file number, (d) the number of shares of each class of capital stock outstanding as shown by the most recent report or statement published by the Company, and (e) whether the Company has filed the reports required to be filed under the Exchange Act for a period of at least ninety (90) days prior to the date of such certificate and in addition has filed the most recent annual report required to be filed thereunder.

Certificate from Registration Rights Agreement

This REGISTRATION RIGHTS AGREEMENT (this Agreement), dated as of March 25, 2008, is by and between CORCEPT THERAPEUTICS INCORPORATED (the Company) and KINGSBRIDGE CAPITAL LIMITED (the Investor).

Certificate. The Company will, at its expense, forthwith upon the request of any holder of Registrable Securities, deliver to such holder a certificate, signed by the Companys principal financial officer, stating (a) the Companys name, address and telephone number (including area code), (b) the Companys Internal Revenue Service identification number, (c) the Companys Commission file number, (d) the number of shares of each class of Stock outstanding as shown by the most recent report or statement published by the Company, and (e) whether the Company has filed the reports required to be filed under the Exchange Act for a period of at least ninety (90) days prior to the date of such certificate and in addition has filed the most recent annual report required to be filed thereunder.

Certificate from Registration Rights Agreement

This REGISTRATION RIGHTS AGREEMENT (this Agreement), dated as of July 19, 2006, is by and between KOSAN BIOSCIENCES INCORPORATED (the Company) and KINGSBRIDGE CAPITAL LIMITED, an entity organized and existing under the laws of the British Virgin Islands, whose registered address is Palm Grove House, 2nd Floor, Road Town, Tortola, British Virgin Islands (the Investor).

Certificate. The Company will, at its expense, forthwith upon the request of any holder of Registrable Securities, deliver to such holder a certificate, signed by the Companys principal financial officer, stating (a) the Companys name, address and telephone number (including area code), (b) the Companys Internal Revenue Service identification number, (c) the Companys Commission file number, (d) the number of shares of each class of Stock outstanding as shown by the most recent report or statement published by the Company, and (e) whether the Company has filed the reports required to be filed under the Exchange Act for a period of at least ninety (90) days prior to the date of such certificate and in addition has filed the most recent annual report required to be filed thereunder.

Certificate from Registration Rights Agreement

This REGISTRATION RIGHTS AGREEMENT (this Agreement), dated as of October 14, 2005, is by and between TERCICA, INC. (the Company) and KINGSBRIDGE CAPITAL LIMITED (the Investor).

Certificate. The Company will, at its expense, forthwith upon the request of any holder of Registrable Securities, deliver to such holder a certificate, signed by the Companys principal financial officer, stating (a) the Companys name, address and telephone number (including area code), (b) the Companys Internal Revenue Service identification number, (c) the Companys Commission file number, (d) the number of shares of each class of Stock outstanding as shown by the most recent report or statement published by the Company, and (e) whether the Company has filed the reports required to be filed under the Exchange Act for a period of at least ninety (90) days prior to the date of such certificate and in addition has filed the most recent annual report required to be filed thereunder.

Certificate from Registration Rights Agreement

This REGISTRATION RIGHTS AGREEMENT (this Agreement), dated as of August 4, 2005, is by and between NUVELO, INC. (the Company) and KINGSBRIDGE CAPITAL LIMITED (the Investor).

Certificate. The Company will, at its expense, forthwith upon the request of any holder of Registrable Securities, deliver to such holder a certificate, signed by the Companys principal financial officer, stating (a) the Companys name, address and telephone number (including area code), (b) the Companys Internal Revenue Service identification number, (c) the Companys Commission file number, (d) the number of shares of each class of Stock outstanding as shown by the most recent report or statement published by the Company, and (e) whether the Company has filed the reports required to be filed under the Exchange Act for a period of at least ninety (90) days prior to the date of such certificate and in addition has filed the most recent annual report required to be filed thereunder.