NCOH Strategic Research Theme Sample Clauses

NCOH Strategic Research Theme. Tackling Antimicrobial Resistance (NCOH-AMR) The NCOH-AMR addresses the following challenge: To decrease the morbidity and mortality of antibiotic-resistant bacterial infections in humans, through use-inspired One Health research on AMR. The global emergence of antibiotic resistance, coupled to the increasing complexity of medical care relying on effective prevention and treatment options for bacterial infections, poses a serious challenge for modern medicine in the developed world. The success of antibiotics in the treatment and prevention of bacterial infections is now rapidly leading to their downfall. Exposing bacteria in humans and animals for decades to these ‘wonder drugs’ has augmented the emergence of resistance against all available antibiotics through selection of resistant mutants and cross-species transmission of bacteria, plasmids and resistance genes. Spill of human and animal waste also contaminates environmental niches maintaining continuous exposure of humans and animals (for some examples see Box 1). Better understanding the dynamics of these events, followed by effective interventions, is one of the cornerstones towards a sustainable solution for this global challenge.
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NCOH Strategic Research Theme. Emerging Infectious Diseases Preparedness (NCOH-EID) NCOH-EID brings together Dutch top scientists on emerging infectious diseases (EID) under one virtual roof with a common strategic research agenda addressing the following challenge: To improve preparedness for (re-) emerging infectious disease outbreaks by developing improved EID prediction, detection, and prevention and control strategies in a time frame that is compatible with fast-spreading EID, based on fundamental research insights into host, microbial, and environmental factors leading to disease (re-) emergence. The past decades witnessed the emergence of novel infectious diseases and changing patterns in existing diseases across the globe with substantial impact on humans and animals, as well as the economy (for some examples see Box 2). Box 2: Notable examples of (re-)emerging infectious diseases are the incursions into Europe of avian influenza H5N1, H7N9 and H5N8, Bluetongue virus, and Schmallenberg virus, with major impact on the animal sector, and the human disease outbreaks following cross-species jumps of zoonotic pathogens, for instance the SARS, MERS, and Ebola virus. The economic losses caused by the SARS CoV outbreak, that affected 8000 persons of which 10% died, has been estimated to amount to tens of billions of US Dollars, primarily due to travel restrictions, effects on tourism and trade. Similarly, the Ebola outbreak has almost completely paralyzed the already weak health systems in the three affected countries, and led to the death of an estimated 9% of the total medical workforce. Moreover, it triggered massive global response, with high costs to hospitals and public health systems preparing for potential travel associated cases or ill healthcare workers. Avian influenza emergence in China led to a 25% drop in the income of the Kentucky fried chicken chain, despite clear public health messages that the risk to consumers was negligible. While these are seemingly exotic examples, EID outbreaks closer to home are also possible, with the recent examples of Q-fever, the increasing prevalence of hepatitis E human cases for which main modes of transmission to humans remain to be determined, and the presence of swine influenza from which the pandemic influenza H1N1 in 2009 emerged. The Netherlands experienced the largest Q fever outbreak between 2007 and 2010 ever reported, involving more than 4000 human cases. Epidemiological and molecular analysis revealed dairy goats at the source o...
NCOH Strategic Research Theme. Smart and Healthy Farming (NCOH-SHF) NCOH-SHF addresses the following challenge: To reduce or eliminate human health risks arising from livestock and food production through research contributing to more healthy animals, early signalling of animal health parameters, and smart and healthy farming practices. Animal husbandry and animal products are important to fulfil the global demand for high-quality food, and remain an important commodity despite occasional outbreaks. Livestock production is currently facing enormous challenges, not only related to animal disease threats, but also to the fact that the license to produce is under debate due to risks to public health and sub-optimal animal welfare, as well as environmental degradation. Socio-economic demands for healthy livestock production chains emphasize that animals should be kept under conditions that (i) optimize animal health and prevent development of disease and health problems (without systematic use of antibiotics), (ii) minimize the influence on the environment, and (iii) provide an end-product that is safe for the consumer. Public health risks associated with livestock production and processing either occur through: • Direct occupational health risks in livestock production and processing; • Contamination in stages of the food chain, either directly (meat) or indirectly, through contact with environmental contamination; a well-recognized global health threat is the potential transmission of pathogens through the food chain. These can be animal pathogens, but also combinations of human and animal pathogens for instance when food is contaminated from environmental sources, resulting in exposure of humans to multiple pathogens simultaneously with unforeseeable consequences. A recently completed World Health Organization burden of disease study1 estimated the burden of foodborne disease to be similar to that of major infectious diseases (human immunodeficiency virus-acquired immune deficiency syndrome, malaria and tuberculosis). This points at major vulnerabilities of the food chain, and these come to light with every emerging disease outbreak. • Exposure of individuals, living in the immediate surroundings of livestock producing units, to emissions of (infectious) microbial agents, their toxins or other (non-infectious) particles and waste streams (manure) containing (infectious) microbial agents. A complicating factor for livestock production in the Netherlands is that livestock production takes ...
NCOH Strategic Research Theme. Healthy Wildlife- and Ecosystems (NCOH-HWE) The NCOH-HWE addresses the following challenge: To decrease the detrimental effects of wildlife-related disease on human health, livestock production systems and ecosystems through understanding, anticipation, and (potential) prevention of environmental factors driving spread of wildlife diseases using an integrated, multidisciplinary approach.

Related to NCOH Strategic Research Theme

  • Technology Research Analyst Job# 1810 General Characteristics Maintains a strong understanding of the enterprise’s IT systems and architectures. Assists in the analysis of the requirements for the enterprise and applying emerging technologies to support long-term business objectives. Responsible for researching, collecting, and disseminating information on emerging technologies and key learnings throughout the enterprise. Researches and recommends changes to foundation architecture. Supports research projects to identify and evaluate emerging technologies. Interfaces with users and staff to evaluate possible implementation of the new technology in the enterprise, consistent with the goal of improving existing systems and technologies and in meeting the needs of the business. Analyzes and researches process of deployment and assists in this process.

  • Technology Transfer Subject to the terms of the Development Supply Agreement, as soon as reasonably practicable, but in no event later than the fifth (5th) anniversary of the Effective Date, Alnylam shall initiate a technology transfer to MedCo, or to its Third Party manufacturer(s) of Licensed Product, selected by MedCo and reasonably acceptable to Alnylam, of Alnylam Know-How that is reasonably necessary or useful for the Manufacture of the Licensed Product, and shall make available its personnel on a reasonable basis to consult with MedCo or such Third Party manufacturer(s) with respect thereto, all at MedCo’s expense, including the Costs reasonably incurred by Alnylam in connection with such technology transfer activities. MedCo shall reimburse Alnylam such Costs incurred with respect to such Manufacturing technology transfer within [***] days after receipt of an invoice therefor. Alnylam and its Affiliates shall keep complete and accurate records in sufficient detail to enable the payments payable hereunder to be determined. Alnylam shall not be required to perform technology transfer to more than one Third Party manufacturer for each stage of the Licensed Product supply chain (i.e., Bulk Drug Substance, Bulk Drug Product and Finished Product). Promptly after MedCo’s written request, Alnylam shall use Commercially Reasonable Efforts to assign to MedCo any manufacturing agreement between Alnylam and a Third Party that is solely related to the manufacture of Licensed Products. Such assignment shall be subject to the terms and conditions of such agreement, including any required consents of such Third Party and MedCo’s written agreement to assume all the obligations of Alnylam under such agreement to be undertaken after such assignment, but Alnylam shall remain solely responsible for its obligations under such agreement arising prior to such assignment. Except as provided in the immediately preceding sentence, MedCo shall be solely responsible for contracting with such Third Party manufacturer (and any other Third Party manufacture to whom Alnylam has initiated technology transfer as set forth in this Section 5.3) for the supply of such Licensed Product and Alnylam shall have no obligations under such agreement between MedCo and such Third Party manufacturer. Alnylam shall use Commercially Reasonable Efforts to obtain any such consent in a form reasonably acceptable to MedCo.

  • Research and Development (i) Advice and assistance in relation to research and development of Party B;

  • University strategies Our aspirations and key priorities for enhancing teaching and learning quality We aspire to produce flexible and creative thinkers – leaders for Australia and the wider world. To do this, we need to provide an enriching university experience that equips our graduates with enquiring minds and essential life skills in critical thinking and communication. Our students must have excellent opportunities to participate in co-curricular activities if they wish to do so, and have access to high quality infrastructure and support services. To maintain and build on our success in these areas, our short- to medium-term priorities will focus on three complementary areas. Our plans Renewing our curriculum and learning environments We will continue to implement our curriculum renewal strategy by pursuing a coordinated University-wide process of reform of our courses. At the heart of this strategy lies a commitment to providing an 'engaged enquiry' learning experience for our students, in order to strengthen the development of our graduate attributes. Such learning experiences reflect the University’s reputation for both research and community engagement. They are consistent with our students' expectations as learners and our staff as teachers. 'Engaged enquiry’ provides the vehicle by which we will focus on further enhancing the research and inquiry learning outcomes that are central to our graduate attributes. We are currently mapping students’ reports of research- enriched learning experiences, and working with our Engaged Enquiry Scholars networks to identify and disseminate examples of approaches that xxxxxx effectively the development of research skills by our undergraduate students. The second aspect of our ‘engaged enquiry' curriculum strategy is the embedding of community- engaged learning, including work-integrated learning (WIL), in our curricula. This commitment will involve professional disciplines in particular, in further strengthening the engagement of employers in our teaching and curriculum development, and in further developing our pedagogical expertise in this area to inform curriculum renewal. One example of how we are pursuing this agenda is seen in the establishment of a new WIL research group in the Faculty of Health Sciences. Our approach to curriculum renewal will continue to be both holistic and sustainable. We will use University-wide agreed principles to link our faculties’ curriculum renewal work explicitly to the need for responsiveness to external drivers. These include employer needs, accreditation and regulatory accountabilities, changes in student and employment market needs, and the renewal of our physical and virtual teaching infrastructure outlined in Section 4.4.2 (Teaching and Learning Infrastructure) of this compact. Building on the findings of recent Office for Learning and Teaching (OLT) projects we will seek, through implementation of our new assessment policy, to develop our assessment practices to provide better direct evidence of student achievement of our graduate attributes. Our unit and course evaluation processes will provide clear accountability mechanisms to assist in monitoring students’ development of graduate attributes, including generic skills. During the next phase of reform we will implement a systematic process of faculty-led curriculum reviews, and support faculties to refine their understanding of how research-enriched and community-engaged pedagogies can deliver an engaged enquiry experience for students in different disciplines. This pedagogical work will build on the substantial body of excellent practice already in place in many parts of the University. It will also respond to the outcomes of relevant OLT projects, and will be supported by the development of new institutional datasets on our students’ experiences of the development of graduate attributes through engaged enquiry. There will also be new support for enhanced curriculum governance and review through our central teaching and curriculum committees. We will initiate new strategic curriculum projects and establish additional Teaching Scholars Networks to develop agreed curriculum benchmark standards and xxxxxx curriculum and teaching expertise across the faculties. Through collaboration between disciplines and faculties, our curriculum renewal projects will generate new resources and benchmark standards for use in future curriculum reviews and professional development for our staff. Enhancing teaching quality, support and recognition Alongside and supporting the process of curriculum reform is our work on enhancing and further valuing the high quality of teaching and curriculum across the institution. Following consistent improvements over the past five years in our performance against measures of student experience of their courses (Student Course Experience Questionnaires) we recently developed and introduced the first stage of a new University-wide strategy to enhance the quality of our students' experiences in all units of study. Through compacts on faculty teaching standards, we will continue to use a University-agreed teaching standards framework to help faculties address teaching quality issues. This process will be supported by new institutional data reporting processes. Each year, faculties will be required to negotiate improvement targets aligned to University-agreed standards and their own strategic priorities, and will be supported to identify and address quality issues. Longer term, we will embed these compacts in an annual cycle of planning, reporting and monitoring. We will extend the scope of our faculty teaching compacts to draw on a broader range of data than that relating to units of study, and will include additional institutional standards in relation to other institutional teaching priorities, such as engaged enquiry. During the life of our 2014-16 compact, we will extend this support to individual teachers through the rollout of the new Academic Planning and Development process for teaching, as well as through research and ongoing enhancements to our range of professional development opportunities for University teachers and research higher degree supervisors. This will complement the University’s enhancement and support for the career opportunities for teachers through the University’s new academic promotion process. It will also allow us to develop further the University and faculty teaching award and grants schemes. We will build institutional recognition for our talented teachers by engaging them in our curriculum renewal process, connecting them with each other through the establishment of additional Teaching Scholars Networks and by providing opportunities for their further professional development. Recognition of the importance of excellence in teaching will also be supported by the annual Sydney Teaching Colloquium, a successful initiative launched in 2011, which brings together the university teaching community to celebrate their achievements, critically debate key educational initiatives and share their expertise and exemplary practice. Improving the student experience Our Teaching and Learning strategies recognise that student wellbeing and the general quality of their experience while at university must underpin our efforts to improve teaching and learning. During the timeframe of our 2014-16 compact, we will deliver a greater coherence across all aspects of the student experience. This will include improvements in priority areas such as: enhancing the student enrolment and ongoing administration process by completing the Sydney Student project providing specialist services and resources to support the emotional and mental wellbeing of students, such as personal counselling and psychological resilience resources establishing early identification systems for students, particularly those from underrepresented groups and international students, who may be struggling in the early phase of their studies developing and expanding existing formal and informal support networks through consistent mentor training and staff development programs collaborating with our student representative organisations, to ensure that income from the Student Services and Amenities Fee (SSAF) is used effectively to enhance access to amenities such as sports and cultural activities, the social dimensions of clubs and societies, and also to improve the quality and affordability of food and beverages available on campus endeavouring to maintain the high ratings we have received from the National Union of Students for our approach to involving students in decisions about the allocation of SSAF funds expanding affordable accommodation options around our campuses. Note: All calendar year references below relate to projects and awards in that calendar year. Principal Performance Indicators Baseline 2012 Progressive Target 2013 Progressive Target 2014 Progressive Target 2015 Target 2016

  • Collaboration We believe joint effort toward common goals achieves trust and produces greater impact for L.A. County’s youngest children and their families.

  • Design Development Phase Services 3.3.1 Based on the Owner’s approval of the Schematic Design Documents, and on the Owner’s authorization of any adjustments in the Project requirements and the budget for the Cost of the Work, the Architect shall prepare Design Development Documents for the Owner’s approval. The Design Development Documents shall illustrate and describe the development of the approved Schematic Design Documents and shall consist of drawings and other documents including plans, sections, elevations, typical construction details, and diagrammatic layouts of building systems to fix and describe the size and character of the Project as to architectural, structural, mechanical and electrical systems, and other appropriate elements. The Design Development Documents shall also include outline specifications that identify major materials and systems and establish, in general, their quality levels.

  • Research Design The data generated by excavations at the prehistoric site(s) will be used to examine at least three topics: (1) chronology; (2) technology; and (3) subsistence practices. Insights into changing patterns of community organization may also be granted, as may insights into changes in social organization. The data recovered will then be compared to data from other regional sites.

  • Project Development a. Collaborate with COUNTY and project clients to identify requirements and develop a project Scope Statement.

  • Staff Development ‌ The County and the Association agree that the County retains full authority to determine training needs, resources that can be made available, and the method of payment for training authorized by the County. Nothing in this subsection shall preclude the right of an employee to request specific training.

  • Software Development Software designs, prototypes, and all documentation for the final designs developed under this agreement must be made fully transferable upon direction of NSF. NSF may make the software design, prototype, and documentation for the final design available to competitors for review during any anticipated re-competition of the project.

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