Modified Compound definition

Modified Compound means (i) a compound that results from the Compound Modification process that is not a Bi-Functional Compound or (ii) any Functional Fragment of such compound.
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Modified Compound means any article of potential research, therapeutic, prophylactic, diagnostic or agricultural interest, including nanobody derivatives, or engineered modifications containing a ligand- binding domain or utilizing a complementarity determining region or any other sub-portion of an Original Compound, either in its original form or as modified or optimized for commercial utility. Such optimization could include, but is not limited to, protein fusions to create new activity or functionality for any purpose, alterations or fusions to increase expression, modify stability, PK, or biodistribution; functionalization with active moieties or toxins; individual or multiple amino-acid mutations to increase binding or stability, reduce immunogenicity or toxicity, or otherwise enhance suitability for the commercial utility.
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Modified Compound means any bivalent, monospecific, monoclonal, and monoepitopic antibody derived from the Compound having [*****]. Under this Section, a Modified Compound may be made by employees of Dermira or its Affiliates solely or jointly with a Third Party, including a Sublicensee, or solely by a Sublicensee (a “Dermira Modified Compound”), by employees of Roche or its Affiliates solely or jointly with a Third Party (a “Roche Modified Compound”), or jointly by employees of Dermira and Roche or Affiliates of either with or without a Third Party (a “Joint Modified Compound”).
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Examples of Modified Compound in a sentence

  • Prior to the any use for Commercial Purposes, each Modified Compound shall be identified by INSTITUTION, by USER or otherwise to UNIVERSITY.

  • Description of the Modified Compound: Revenue Sharing Determination: The undersigned duly authorized representatives have signed this Exhibit B to be effective as of the date of the last signature below.

  • Appendix B MODIFIED COMPOUNDS AND REVENUE SHARE PERCENTAGES UNIVERSITY, acting through its Office of Technology Development, and INSTITUTION hereby agree to the following revenue-sharing agreement as to the Modified Compound described herein, subject to all of the terms and conditions of Article 6 of the Agreement (and related definitions), all of which are incorporated into this Appendix B by reference.

  • UNIVERSITY acting through its Office and Technology Development for purposes of administering this Article 6, and INSTITUTION shall discuss in good faith and agree on the appropriate revenue-sharing with respect to such Modified Compound pursuant to Section 6(c) prior to INSTITUTION licensing/optioning or transferring any such Modified Compound or any Patent Rights covering such Modified Compound for Commercial Purposes.

  • For each Modified Compound, UNIVERSITY and INSTITUTION agree to enter into the attached Appendix B to provide a description of the Modified Compound and the revenue-sharing determination made pursuant to Section 6(c) hereof.

  • Institution shall describe Modified Compounds derived from Original Compounds and shall indication which revenue sharing agreement, described in Section 4.1, is appropriate to Modified Compound.


More Definitions of Modified Compound

Modified Compound means a Compound that Pieris modifies pursuant to Section 3.4.
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Modified Compound means with respect to the Research Period or thereafter any chemical substance prepared by ONO, which modulates the production of [CONFIDENTIAL TREATMENT REQUESTED] and [CONFIDENTIAL TREATMENT REQUESTED] by binding selectively to melanocortin receptor 1, using chemical synthesis through use of the TREGA Technology or CONFIDENTIAL TREATMENT REQUESTED
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Modified Compound means any analog, derivative, or modified version of a Collaboration Compound that is generated by or on behalf of Lilly or any of its Affiliates (other than by Merus or its Affiliates during the Research Term), in each case that is directed against the applicable Lilly Target Pair, but excluding such Lilly Target Pair together with a third Target (and, for clarity, Lilly is not licensed under the terms of this Agreement to generate any such multi-specific compound), and excluding any analog, derivative, or modified version of a Collaboration Compound where the modification is [*]. For clarity, where a Modified Compound generated by or on behalf of Lilly or any of its Affiliates is [*], such compound shall be considered a Modified Compound for all purposes hereunder.
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Modified Compound has the meaning set forth in Section 5.2.
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Related to Modified Compound

  • Back-Up Compound means, with reference to any particular Development Candidate or Drug Product Candidate, a Compound which (a) has the same principal mode of action (i.e., Potentiator or Corrector) as that Development Candidate or Drug Product Candidate; and (b) was among the group of Compounds, identified by VERTEX as potential additional lead molecules having the same principal mode of action, from which the Development Candidate was selected.

  • Licensed Compound means (a) 3,4-Diaminopyridine, the chemical structure of which is set forth on Exhibit B-2; and (b) any derivatives, isomers, metabolites, prodrugs, acid forms, base forms, salt forms, or modified versions of such compound in (a).

  • Collaboration Compound means any of the following: (a) FG-4592, (b) any HIF Compound (other than FG-4592) that is added to this Agreement pursuant to Section 3.6, and (c) any salts, esters, complexes, chelates, crystalline and amorphous morphic forms, pegylated forms, enantiomers (excluding regioisomers), prodrugs, solvates, metabolites and catabolites of any of the foregoing ((a) or (b)).

  • Lead Compound means any compound of lead other than galena which, when treated in the manner described below, yields to an aqueous solution of hydrochloric acid a quantity soluble lead compound exceeding, when calculated as lead monoxide, five percent of the dry weight of the portion taken analysis.

  • Licensed Compounds means any EZH2 Compound(s) that is:

  • Compound means the taking of two or more ingredients and fabricating them into a single

  • Exempt compound means the same as defined in Rule 2.

  • Product Candidate means each of MYO-101, MYO-102, MYO-103, MYO-201 and MYO-301, as defined on Exhibit B, in each case in any form or formulation.

  • Development Candidate means a Compound that meets the Development Candidate Criteria for the initiation of a Development Program for the treatment of CF, and which is the subject of a notice from Vertex to CFFT that Vertex intends to commence formal pre-clinical development of the Compound in the Field pursuant to the provisions of Section 3.1 hereof.

  • Collaboration Target means the Initial Collaboration Targets set forth on Exhibit F and any Additional Target or Substitute Target that is selected in accordance with Section 3.3 of this Agreement.

  • Certified components means components of X-ray systems which are subject to regulations promulgated under Public Law 90-602, the “Radiation Control for Health and Safety Act of 1968,” the Food and Drug Administration.

  • Compounds means a small molecule HMT inhibitor.

  • Collaboration Product means a pharmaceutical product containing or comprising Compound in any dosage form alone, or in combination with, one or more other pharmaceutically active ingredients, and any and all Improvements thereto.

  • Replacement Candidate means any Candidate Introduced by the Agency to the Client to fill the Engagement following the Introduction of another Candidate whose Engagement either did not commence or was terminated during the first 12 weeks of the Engagement;

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.

  • Drug Substance means an active ingredient that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient.

  • MSAA Indicator Technical Specifications document means, as the context requires, either or both of the document entitled “Multi-Sector Service Accountability Agreement (MSAA) 2019-20 Indicator Technical Specifications November 5, 2018 Version 1.3” and the document entitled “Multi-Sector Service Accountability Agreement (MSAA) 2019-20 Target and Corridor-Setting Guidelines” as they may be amended or replaced from time to time;

  • Drug Product means a specific drug in dosage form from a known source of manufacture, whether

  • Biosimilar Product means, with respect to a Licensed Product in any country, any biosimilar product sold by a Third Party not authorized by or on behalf of Celgene, its Affiliates or Sublicensees, (a) that is a biosimilar biological product, as defined in 21 USC 379j-51 (or any successor or replacement thereof), a similar biological medicinal product, as defined in Annex I to Directive 2001/83/EC (or any successor or replacement thereof), or any similar biosimilar or generic product under the Laws of any country or jurisdiction, or (b) regarding which Regulatory Approval is obtained by referencing Regulatory Data of such Licensed Product.

  • Hemp product means the same as that term is defined in § 3.2-4112.

  • low protein modified food product means a food product that is specially formulated to have less than one gram of protein per serving and is intended to be used under the direction of a Practitioner for the dietary treatment of an inherited metabolic disease, but does not include a natural food that is naturally low in protein; and

  • Biological Samples means any physical samples obtained from Study Participants in accordance with the Protocol for the purposes of the Study.

  • Diagnostic Product means In Vitro Diagnostics, In Vivo Diagnostic Agents and any product used for Diagnosis.

  • Non-Microsoft Product means any third-party-branded software, data, service, website or product, unless incorporated by Microsoft in a Product.

  • medicinal product means any substance or combination of substances presented for treating or preventing disease in human beings or animals and any substance or combination of substances which may be administered to human beings or animals with a view to making a medical diagnosis or to restoring, correcting or modifying physiological functions in humans or in animals;

  • Compound of Concern means a contaminant that, based on generally available information, may be emitted to the atmosphere in a quantity from any source at the Facility that is significant either in comparison to the relevant Ministry Point of Impingement Limit or if a Ministry Point of Impingement Limit is not available for the compound then, based on generally available toxicological information, the compound has the potential to cause an adverse effect as defined by the EPA at a Point of Impingement.