Binding Domain definition

Binding Domain means the region of a CAR that binds to the antigen targeted by such CAR (or if such CAR is multivalent, binds to one of the epitopes targeted by such CAR), such region comprised of one or more CDRs, and most commonly consisting of XXXX0, XXXX0 and CDRH3.
Sample 1Sample 2
Binding Domain means the region of an Antibody that binds to the antigen targeted by such Antibody (or if such Antibody is multivalent, binds to one of the epitopes targeted by such Antibody) [***].
Sample 1
Binding Domain means the portion of a pharmaceutical or diagnostic product that binds to an antigen or a cell surface molecule, including a variable domain thereof. “4-1BB Binding Domain” refers to a Binding Domain that specifically binds to 4-1BB, [***]. “4-1BB” is also referred to a “CD137” and means tumor necrosis factor receptor superfamily member 9 (Ensembl gene ID: ENSG00000049249), [***].
Sample 1

Examples of Binding Domain in a sentence

  • Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding.

  • Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor- Binding Domain that Escape Antibody Recognition.

  • Torbeev, Aggregation and Amyloidogenicity of the Nuclear Coactivator Binding Domain of CREB-Binding Protein, Chem.–Eur.

  • Wang, “NMR Solution Structure of a Peptide from mdm-2 Binding Domain of the p53 protein that Is Selectively Cytotoxic to Cancer Cells,” Biochemistry, vol.

  • Computational Simulations Reveal the Binding Dynamics between Human ACE2 and the Receptor Binding Domain of SARS-CoV-2 Spike Protein.

  • Mutations in the Substrate Binding Domain of the Escherichia Coli 70 Kda Molecular Chaperone, DnaK, Which Alter Substrate Affinity or Interdomain Coupling11Edited by M.

  • The SARS Coronavirus S Glycoprotein Receptor Binding Domain: Fine Mapping and Functional Characterization.

  • A Folding Nucleus and Minimal ATP Binding Domain of Hsp70 Identified by Single-Molecule Force Spectroscopy.

  • Bloom, Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding.

  • Nanomechanics of the Substrate Binding Domain of Hsp70 Determine Its Allosteric ATP-Induced Conformational Change.

Related to Binding Domain

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  • Existing Confidentiality Agreement shall have the meaning set forth in Section 6.6.

  • Addendum and Assignment Agreement The Addendum and Assignment Agreement, dated as of January 31, 1995, between MLCC and the Master Servicer.

  • Acceptable Confidentiality Agreement means a confidentiality agreement that contains provisions that are no less favorable in the aggregate to the Company than those contained in the Confidentiality Agreements; provided, that such agreement and any related agreements shall not include any provision calling for any exclusive right to negotiate with such party or having the effect of prohibiting the Company from satisfying its obligations under this Agreement.

  • Confidentiality Agreements is defined in Section 5.5(e) hereof.

  • Confidential or Proprietary Information means any secret, confidential or proprietary information of the Company or an affiliate (not otherwise included in the definition of a Trade Secret under this Employment Agreement) that has not become generally available to the public by the act of one who has the right to disclose such information without violation of any right of the Company or its affiliates.

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  • Noncompetition Agreements as defined in Section 2.8(a)(iv). "Occupational Safety and Health Law"--any law or regulation designed to provide safe and healthy working conditions and to reduce occupational safety and health hazards, and any program, whether governmental or private (including those promulgated or sponsored by industry associations and insurance companies), designed to provide safe and healthful working conditions.

  • Purchaser Confidential Information means all confidential or proprietary documents and information concerning the Purchaser or any of its Representatives; provided, however, that Purchaser Confidential Information shall not include any information which, (i) at the time of disclosure by the Company, the Seller Representative or any of their respective Representatives, is generally available publicly and was not disclosed in breach of this Agreement or (ii) at the time of the disclosure by the Purchaser or its Representatives to the Company, the Seller Representative or any of their respective Representatives, was previously known by such receiving party without violation of Law or any confidentiality obligation by the Person receiving such Purchaser Confidential Information. For the avoidance of doubt, from and after the Closing, Purchaser Confidential Information will include the confidential or proprietary information of the Target Companies.

  • Confidential Information has the meaning set forth in Section 6.1.

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