Nature and Purpose of the Study. The Study shall be conducted in order to document the clinical benefits of the Product on aging • and aged skin, particularly with regard to wrinkles.
Nature and Purpose of the Study. You are being asked to participate in this study because you have been diagnosed with pulmonary arterial hypertension (PAH) and you are receiving drug therapy for PAH. The purpose of this study is to determine if a naturally occurring hormone called dehydroepiandrosterone (DHEA) can reduce the negative effects PAH has on the right side of the heart. Previous studies of DHEA levels in the blood have shown that DHEA levels are significantly lower in people with PAH versus people who do not have PAH and that these lower levels are linked to right heart failure. A small study of DHEA treatment in COPD patients with pulmonary hypertension showed some benefit. Treatment with DHEA may therefore be beneficial for right heart function in PAH patients. Your body naturally produces DHEA in the adrenal gland. In turn, DHEA helps produce other hormones, including testosterone and estrogen. Many PAH researchers believe there is a link between sex hormones and PAH. Natural DHEA levels peak in early adulthood and then slowly fall as you age. A synthetic version of DHEA is available as a supplement for oral use, as a tablet. It is available for sale at many local retailers and on-line, but the purity of those supplements may not always be tested or guaranteed by the manufacturer. The DHEA that will be used in this study will be supplied by a manufacturer that employs good manufacturing practices (GMP) and will be independently tested for purity to assure the tablets contain the correct amount of DHEA. We expect to enroll 26 subjects, 13 women and 13 men, into this study at Rhode Island Hospital. The study is sponsored by the National Institutes of Health (NIH).
Nature and Purpose of the Study. You are being asked to take part in a research project because you are between the ages of 18 and 70 and you meet all of the other eligibility criteria for this study. The purpose of this study is to examine whether adding phone coaching to an Internet-based weight loss program can improve weight loss outcomes at 4 months and 1 year. We expect to enroll approximately 450 individuals. The study is sponsored by a National Institutes of Health grant awarded to Xx. Xxxxxxx Xxxxx.
Nature and Purpose of the Study. Your child is being asked to take part in a research project to develop and evaluate a text-message based intervention to help teens deal with stress and fights, and to prevent depression. In this part of the study, we will ask for your child’s participation in the program. We expect to enroll 120 subjects into this study. The study is sponsored by the National Institute of Mental Health.
Nature and Purpose of the Study. You are being asked to take part in a research project because you are between the ages of 18 and 60 and you meet all of the other eligibility criteria for this study. The purpose of this study is to examine the relationships between how you feel, exercise and eating. We expect to enroll approximately 150 individuals. The study is sponsored by a National Institutes of Health grant awarded to Xx. Xxxxxxx Xxxxx.
Nature and Purpose of the Study. You are being asked to take part in a research project because you are currently participating in The Xxxxxx Hospital’s or The Newport Hospital’s Cardiac Rehabilitation (CR). You are between the ages of 21 and 75 with a body mass index (BMI) of 27-45 kg/m2. You also speak English and have in-home access to an Internet-connected device such as a home personal computer, tablet, or smartphone. You are currently participating in The Xxxxxx Hospital’s or Newport Hospital’s Phase- II (outpatient) CR. Xx. Xx, the medical director of CR, has declared you medically safe to participate in this program. The purpose of this study is to evaluate online program and new technology-based tools that may help CR patients lose weight. We expect to enroll 160 subjects into this study. The study is sponsored by the National Heart, Lung, and Blood Institute.
Nature and Purpose of the Study. You are being asked to take part in a research project because you are a man who reports having exchanged sex for money or drugs with another man, you are 18 years of age or older, and you are HIV-negative. The purpose of this study is to determine if a program called “PrEPare for Work” will help make pre-exposure prophylaxis (PrEP) more effective in preventing HIV among men who exchange sex for money or drugs with another man, or male sex workers (MSWs). PrEP is a medication called Truvada that is taken daily to prevent HIV infection. This medication has been approved by the United States Food and Drug Administration (FDA) for this purpose. In order to promote the effectiveness of PrEP, we are testing a program called PrEPare for Work to see how well it helps people stay on PrEP once they start taking it. As part of this study you will be asked to sign a medical release so that your medical records regarding your PrEP treatment can be accessed for study purposes. Completion of this release is voluntary. We expect to enroll 130 subjects into this study. The study is being conducted by researchers at Brown University, The Xxxxxx Hospital, and Project Xxxxx, and is sponsored by the National Institutes of Health.
Nature and Purpose of the Study. You are being asked to take part in a research project because you have been admitted to the hospital with an acute exacerbation of chronic obstructive pulmonary disease (AE-COPD). Chronic obstructive pulmonary disease (COPD) refers to two long-term lung diseases - chronic bronchitis and emphysema - that often occur together. COPD makes it hard for you to breathe. Tubes called airways carry air into and out of your lungs. If you have COPD, these airways may become partly blocked from swelling or mucus. AE-COPD is a flare-up of your COPD during which you may feel more short of breath, develop wheezing and a cough or worsened cough. AE-COPD can be brought on by an infection in your lungs or from exposure to something that irritates the lungs like cigarette smoke, smog and other air pollution, strong fumes from scented products, cold air or hot, humid air, or pollens that trigger allergies. Treatment for AE-COPD usually includes nebulizer breathing treatments, steroids and, if an infection caused the flare-up, antibiotics. Nebulizer treatments are a type of treatment that delivers medication to your lungs – you breathe the medication in. The medication is usually a bronchodilator (medication that helps open the airways). Typically, a nebulizer treatment is given with either a hand-held device or through a mask. Liquid medication is placed in a small cup in the device and then oxygen is blown into it to make a mist you can breathe in. In standard nebulizers (SN) the flow of medication mist is constant. This means the medication is being blown around even when you are not inhaling it. The purpose of this study is to compare the use of a standard nebulizer (SN) with what is called a breath actuated nebulizer or BAN. The BAN device is designed so that the medication mist is only released when you take a breath on the device. This may result in delivering more of the medication to your lungs than with a standard nebulizer. We are conducting this study to determine if the BAN device will reduce the number of nebulizer treatments needed during hospitalization in patients with AE-COPD as compared to a standard nebulizer. Both SN and BAN are FDA approved for the delivery of nebulizer treatments. However, Rhode Island Hospital currently does not use BAN devices to treat AE-COPD. We expect to enroll 150 subjects into this study at Rhode Island Hospital. The study is sponsored by Monaghan Medical Corporation.
Nature and Purpose of the Study. You are being asked to take part in a research project because you are between the ages of 18- and 70-years old, you have overweight or obesity, you have at least one medical condition that is a risk factor for cardiovascular disease (e.g., hypertension, high cholesterol, prediabetes/Type 2 diabetes), and you have no medical conditions that indicate that you should not participate in the study. The purpose of this study conducted by Xxxxxx Xxxxxx, PhD and his colleagues at The Xxxxxx Hospital, is to assess weight-related experiences and behaviors that occur during a 24-week behavioral weight loss and maintenance program. We expect to enroll a total of 40 of subjects into this study, all of whom will be enrolled through The Xxxxxx Hospital. The study is sponsored by The Xxxxxx Hospital.
Nature and Purpose of the Study. You are being asked to take part in a research project because you are 18 years old or older and have been diagnosed with heart failure. This is a preliminary experimental study designed to explore whether mindfulness training can improve the ability to take medications regularly. Mindfulness training involves learning to focus the attention and become aware of body sensations, emotions, and thoughts as well as of events happening in the environment surrounding you at each given moment. We expect to enroll 50 patients into this study. Your participation in this research study, should you enroll, will last 6 months. The study is sponsored by the National Heart, Lung, and Blood Institute.
