Temporal. Company warrants and represents that the occurrence in or use by the Software of any dates or times (“Temporal Elements”), including without limitation any date with a year specified as “99” or “00” regardless of other meanings attached to these values, any date and any time change related to daylight savings time or changes in time zones will not adversely affect its performance with respect to date and time-dependent data, computations, output, or other functions (including, without limitation, calculating, comparing, and sequencing) and that the Software will create, store, process, and output information related to or including Temporal Elements without errors or omissions and at no additional cost to Saint Luke’s. At Saint Luke’s request, Company will provide sufficient evidence to demonstrate the adequate testing of the Software to meet the foregoing requirements. Further, at no cost to Saint Luke’s, Company shall support the Software through any change in time mandated by law.
Temporal. Time (msec) Time (msec) Angle (degrees) Voxel Size (mm3) b Values (sec/mm2) Resolution (sec) Diagnostic MR imaging session Note.—DCE = dynamic contrast enhanced, NA = not applicable, 3D = three dimensional. Table 1 T2 weighted Axial turbo spin-echo 3620 116 180 0.4 3 0.4 3 3.0 NA NA DW Single-shot echo-planar with diffusion modules and fat 2500 91 1.5 3 1.5 3 3.0 0, 50, 500, and 800 NA suppression pulses DCE 3D T1-weighted spoiled gradient echo 34 1.6 14 1.5 3 1.5 3 4.0 NA 2.5 Proton density 3D T1-weighted spoiled gradient echo 800 1.6 8 1.5 3 1.5 3 4.0 NA NA MR-guided biopsy session True FISP True FISP 4.48 2.24 70 1.1 3 1.1 3 3.0 NA NA DW Single-shot echo-planar with diffusion modules and fat 2000 67 1.8 3 1.8 3 4.0 0, 100, 500, and 800 suppression pulses T2 weighted Axial turbo spin-echo 3620 104 120 0.8 3 0.8 3 .0 NA NA included low-signal-intensity areas in the peripheral zone (PZ) and/or a homogeneous low T2 signal intensity area with ill-defined margins or a len- ticular shape within the CG (39). After identification of CSRs on T2-weighted images, the ADC maps and multipara- metric dynamic contrast-enhanced MR imaging color maps transfer constant (Ktrans), extravascular extracellular volume (ve), rate constant (Kep), and washout were analyzed in a color over- lay mode on the T2-weighted images. The generally known features of PCa on dynamic contrast-enhanced MR im- ages (13,40) (high ve, Ktrans, Kep, and negative washout) and areas of restric- tion on ADC maps (especially in the PZ and CG) were used to identify CSRs qualitatively (38). Additionally, after the functional data from DW and dy- namic contrast-enhanced MR imaging were evaluated in relation to the CSR findings on the T2-weigthed images, the DW and dynamic contrast-enhanced MR images were viewed separately and in combination to determine additional CSRs not evident on T2-weighted im- ages. Finally, the information from all the imaging modalities were combined and used to determine the CSRs within the PZ and CG of the prostate (38). diffusion in three directions was mea- sured by using four b values. Finally, the imager software calculated ADC maps automatically (Fig 2). After identification of the CSRs, adjustments were applied to the biopsy device to move the needle sleeve ex- actly toward a CSR (41,42). To control needle sleeve direction, T2-weighted true fast imaging with steady preces- sion (FISP) images were acquired in the axial and sagittal direction. Biopsy was performed in all det...
Temporal. Pulse repetition rate = 100 Hz. • The Amplifier shall be capable of amplifying all input pulse durations and shapes as defined in Section 3. • Temporal extinction level (dynamic range) shall be ≥ 30 dB, measured within a time window of ± 15 ns relative to the centre of the temporal pulse i.e. the measured ASE level shall be at least 30dB lower than the measured peak intensity.
Temporal. 1. All group members will be punctual. Meetings will start five minutes after the agreed start time and everyone should be there and ready by then.
