Renal definition

Renal means pertaining to the kidney.
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Renal. Natrecor may affect renal function in susceptible individuals. In patients with severe heart failure whose renal function may depend on the activity of the renin-angiotensin-aldosterone system, treatment with Natrecor may be associated with azotemia. When Natrecor was initiated at doses higher than 0.01 (micro)g/kg/min (0.015 and 0.03 (micro)g/kg/min), there was an increased rate of elevated serum creatinine over baseline compared with standard therapies, although the rate of acute renal failure and need for dialysis was not increased. In the 30-day follow-up period in the VMAC trial, 5 patients in the nitroglycerin group (2%) and 9 patients in the Natrecor group (3%) required first-time dialysis. Cardiovascular: Natrecor may cause hypotension. In the VMAC trial, in patients given the recommended dose (2 (micro)g/kg bolus followed by a 0.01 (micro)g/kg/min infusion) or the adjustable dose, the incidence of symptomatic hypotension in the first 24 hour was similar for Natrecor (4%) and IV nitroglycerin (5%). When hypotension occurred, however, the duration of symptomatic hypotension was longer with Natrecor (mean duration was 2.2 hours) than with nitroglycerin (mean duration was 0.7 hours). In earlier trials, when Natrecor was initiated at doses higher than the 2-(micro)g/kg bolus followed by a 0.01-(micro)g/kg/min infusion (i.e., 0.015 and 0.030 (micro)g/kg/min preceded by a small bolus), there were more hypotensive episodes and these episodes were of greater intensity and duration. They were also more often symptomatic and/or more likely to require medical intervention (see ADVERSE REACTIONS). Natrecor should be administered only in setting where blood pressure can be monitored closely, and the dose of Natrecor should be reduced or the drug discontinued in patients who develop hypotension (see Dosing Instructions). The rate of symptomatic hypotension may be increased in patients with a blood pressure 100 mm Hg at baseline, and Natrecor should be used cautiously in these patients. The potential for hypotension may be increased by combining Natrecor with other drugs that may cause hypotension. For example, in the VMAC trial in patients treated with either Natrecor or nitroglycerin therapy, the frequency of symptomatic hypotension in patients who received an oral ACE inhibitor was 6%, compared to a frequency of symptomatic hypotension of 1% in patients who did not receive an oral ACE inhibitor. Drug Interactions: No trials specifically examining potential dru...
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Renal calculated creatinine clearance (CrCl) ≥60 mL/min based on the Cockcroft and Gxxxx formula (as defined in Section 3.3) Main Exclusion Criteria: ● Diagnosis of NSCLC or mixed NSCLC and SCLC ● No prior malignancy other than SCLC, carcinoma in situ of the cervix, or nonmelanoma skin cancer, unless that prior malignancy was diagnosed and definitively treated 5 or more years prior to study entry with no subsequent evidence of recurrence. Patients with a history of low grade (Gxxxxxx score ≤6=Grade Group 1) localized prostate cancer will be eligible even if diagnosed less than 5 years prior to study entry Investigational Product Dosage and Administration: One Cycle is 21 Days. Patients will receive 4 cycles of induction LB-100 + atezolizumab/carboplatin/etoposide and then will proceed to maintenance with atezolizumab + LB-100. LB-100: Intravenous (IV) at assigned dose (.83, 1.25, 1.75, 2.33 or 3.10 mg/m2), over 15 minutes, given first, Days 1 & 3 of each cycle during induction and maintenance. Other drugs should be given 1 hour after the end of the LB-100 infusion.
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Examples of Renal in a sentence

  • In connection with the Quarterly Report of American Renal Associates Holdings, Inc.

  • Renal dialysis may be provided in an inpatient hospital setting, in an ambulatory care facility, or in the home on recommendation from a renal dialysis center.

  • Sharp conducts Drug Research spanning from Phase 1 to 4 Human Research Clinical Trials with the focus in the fields of Oncology, Renal and Heart Transplantations, Septic Shock treatment, Infectious Diseases and Anticoagulation.

  • Renal Treatment Centers – Southeast, LP Renal Treatment Centers – West, Inc.

  • If approved for STEMI, AGGRASTAT® would be the first in its class of GPIs to receive such a label in the United States.In previous communication with the Company, the FDA’s Division of Cardiovascular and Renal Drug Products indicated its willingness to review and evaluate this label change request based substantially on data from the On-TIME 2 study, with additional support from published studies and other data pertinent to the use of the AGGRASTAT® HDB regimen in the treatment of STEMI.

  • Renal Care Group, Inc., acting by and through its duly authorized officers, has caused this Stock Option Agreement to be executed, and the Grantee has executed this Stock Option Agreement, all as of the day and year first above written.

  • Total Renal Care of Utah, L.L.C. Total Renal Care Texas Limited Partnership Total Renal Care, Inc.

  • Renal dialysis is covered when medically necessary as ordered by a qualified medical professional.

  • Renal Care Group, Inc., acting by and through its duly authorized officers, has caused this Agreement to be executed, and the Grantee has executed this Agreement, all as of the day and year first above written.

  • Notices to the Corporation must be addressed to: Renal Care Group, Inc.


More Definitions of Renal

Renal calculated creatinine clearance (CrCl) ≥60 mL/min based on the Cockcroft and Gxxxx formula below: Males: Creatinine CL = Weight (kg) x (140 – Age) . (mL/min) 72 x serum creatinine (mg/dL) Females: Creatinine CL = Weight (kg) x (140 – Age) x 0.85 (mL/min) 72 x serum creatinine (mg/dL)
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