Heterozygous Population Post-POC Development Cost Cap definition

Heterozygous Population Post-POC Development Cost Cap means the aggregate amount of the Heterozygous Population Post-POC Development Budget included in the Combination Product Post-POC Development Plan attached hereto as Schedule 1.67, together with any increase thereto agreed to by the Parties in accordance with Section 3.3.7; provided that (i) if AbbVie elects to proceed with the Development of a Triple Combination Product for use in only the Heterozygous Population, then [...***...] percent ([...***...]%) of the “base costs” identified in the Combination Product Post-POC Development Plan shall be counted towards the Heterozygous Population Post-POC Development Cost Cap and (ii) if AbbVie elects to proceed with the Development of a Triple Combination Product for use in both the Heterozygous Population and the Homozygous Population, then [...***...] percent ([...***...]%) of such base costs shall be counted towards the Heterozygous Population Post-POC Development Cost Cap and [...***...] percent ([...***...]%) of such base costs shall be counted towards the Homozygous Population Post-POC Development Cost Cap. As of the Restatement Date, the Heterozygous Population Post-POC Development Cost Cap is [...***...] Dollars ($[...***...]) if AbbVie elects to proceed with the Development of a Triple Combination Product for use in only the Heterozygous Population and [...***...] Dollars ($[...***...]) if AbbVie elects to proceed with the Development of a Triple Combination Product for use in both the Heterozygous Population and the Homozygous Population.
Heterozygous Population Post-POC Development Cost Cap means the aggregate amount of the Heterozygous Population Post-POC Development Budget included in the Combination Product Post-POC Development Plan attached hereto as S chedule 1.67, together with any increase thereto agreed to by the Parties in accordance with Section 3.3.7; provided that (i) if AbbVie elects to proceed with the Development of a Triple Combination Product for use in only the Heterozygous Population, then [...***...] percent ([...***...]%) of the “base costs” identified in the Combination Product Post-POC Development Plan shall be counted towards the Heterozygous Population Post-POC Development Cost Cap and (ii) if AbbVie elects to proceed with the Development of a Triple Combination Product for use in both the Heterozygous Population and the Homozygous Population, then [...***...] percent ([...***...]%) of such base costs shall be counted towards the Heterozygous Population Post-POC Development Cost Cap and [...***...] percent ([...***...]%) of such base costs shall be counted towards the Homozygous Population Post-POC Development Cost Cap. As of the Restatement Date, the Heterozygous Population Post-POC Development Cost Cap is [...***...] Dollars ($[...***...]) if AbbVie elects to proceed with the Development of a Triple Combination Product for use in only the Heterozygous Population and [...***...] Dollars ($[...***...]) if AbbVie elects to proceed with the Development of a Triple Combination Product for use in both the Heterozygous Population and the Homozygous Population.

Related to Heterozygous Population Post-POC Development Cost Cap

  • Total Development Cost means the total of all costs incurred in the completion of a Development, all of which shall be subject to the review and approval by the Credit Underwriter and the Corporation pursuant to this rule chapter, and as further described in Rule 67-48.0075, F.A.C.

  • Cluster development means a contiguous cluster or

  • Development Cost means the total of all costs incurred in the completion of a Development excluding Developer Fee, operating deficit reserves, and total land cost as typically shown in the Development Cost line item on the development cost pro forma.

  • Economic development project means land and existing or planned improvements suitable for use by an industrial or commercial enterprise, or housing development, or the protection of the environment, including, but not limited to, groundwater or surface water. Economic development project includes necessary buildings, improvements, or structures suitable for and intended for or incidental to use as an industrial or commercial enterprise or housing development; and includes industrial park or industrial site improvements and port improvements or housing development incidental to an industrial or commercial enterprise; and includes the machinery, furnishings, and equipment necessary, suitable, intended for, or incidental to a commercial, industrial, or residential use in connection with the buildings or structures.

  • Transit-oriented development means infrastructure improvements that are located within 1/2 mile of a transit station or transit-oriented facility that promotes transit ridership or passenger rail use as determined by the board and approved by the municipality in which it is located.

  • medium term expenditure framework ’ means a budgeting framework applied by the National Treasury which—

  • Best available control technology (BACT means an emissions limitation (including a visible emission standard) based on the maximum degree of reduction for each pollutant subject to regulation under CAA which would be emitted from any proposed major stationary source or major modification which the Department, on a case-by-case basis, takes into account energy, environmental, and economic impacts and other costs, determines is achievable for such source or modification through application of production processes or available methods, systems, and techniques, including fuel cleaning or treatment or innovative fuel combustion techniques for control of such pollutant. In no event shall application of best available control technology result in emissions of any pollutant which would exceed the emissions allowed by any applicable standard under 7 DE Admin. Code 1120 and 1121. If the Department determines that technological or economic limitations on the application of measurement methodology to a particular emissions unit would make the imposition of an emissions standard infeasible, a design, equipment, work practice, operational standard, or combination thereof, may be prescribed instead to satisfy the requirement for the application of best available control technology. Such standard shall, to the degree possible, set forth the emissions reduction achievable by implementation of such design, equipment, work practice or operation, and shall provide for compliance by means which achieve equivalent results.

  • spatial development framework means the Kouga Municipal Spatial Development Framework prepared and adopted in terms of sections 20 and 21 of the Act and Chapter 2 of this By-Law;

  • Target Population means persons with low incomes who have one or more disabilities, including mental illness, HIV or AIDS, substance abuse, or other chronic health condition, or individuals eligible for services provided pursuant to the Lanterman Developmental Disabilities Services Act (Division 4.5 (commencing with Section 4500) of the Welfare and Institutions Code) and may include, among other populations, adults, emancipated minors, families with children, elderly persons, young adults aging out of the foster care system, individuals exiting from institutional settings, veterans, and homeless people.

  • Development Costs means costs incurred to obtain access to reserves and to provide facilities for extracting, treating, gathering and storing the oil and gas from reserves. More specifically, development costs, including applicable operating costs of support equipment and facilities and other costs of development activities, are costs incurred to:

  • Inclusionary development means a development containing both affordable units and market rate units. This term includes, but is not necessarily limited to: new construction, the conversion of a non-residential structure to residential and the creation of new affordable units through the reconstruction of a vacant residential structure.

  • Assigned Annual Special Tax means the Special Tax of that name described in Section D.

  • Temporary clean coal technology demonstration project means a clean coal technology demonstration project that is operated for a period of five years or less and that complies with the SIP and other requirements necessary to attain and maintain the national ambient air quality standards during the project and after the project is terminated.

  • municipal spatial development framework means a municipal spatial development framework adopted by the Municipality in terms of Chapter 5 of the Municipal Systems Act;

  • MSAA Indicator Technical Specifications document means, as the context requires, either or both of the document entitled “Multi-Sector Service Accountability Agreement (MSAA) 2019-20 Indicator Technical Specifications November 5, 2018 Version 1.3” and the document entitled “Multi-Sector Service Accountability Agreement (MSAA) 2019-20 Target and Corridor-Setting Guidelines” as they may be amended or replaced from time to time;

  • Fully Burdened Manufacturing Cost means, with respect to any Licensed Product supplied by or on behalf of NVCR to Zai hereunder if such Licensed Product (or any precursor or intermediate thereof) is manufactured by a Third Party manufacturer [***].

  • Animal feeding operation (“AFO”) means a lot or facility (other than an aquatic animal production facility) where animals have been, are, or will be stabled or confined and fed or maintained for a total of 45 days or more in any 12-month period, and crops, vegetation, forage growth, or post-harvest residues are not sustained in the normal growing season over any portion of the lot or facility [40 CFR § 122.23(b)(1)].

  • Massive Multiauthor Collaboration Site (or “MMC Site”) means any World Wide Web server that publishes copyrightable works and also provides prominent facilities for anybody to edit those works. A public wiki that anybody can edit is an example of such a server. A “Massive Multiauthor Collaboration” (or “MMC”) contained in the site means any set of copyrightable works thus published on the MMC site.

  • Development Site means any parcel or lot on which exists or which is intended for building development other than the following:

  • Anti-Static Product means a product that is labeled to eliminate, prevent, or inhibit the accumulation of static electricity. “Anti-Static Product” does not include “Electronic Cleaner,” “Floor Polish or Wax,” “Floor Coating,” and products that meet the definition of “Aerosol Coating Product” or “Architectural Coating.”

  • Clean coal technology demonstration project means a project using funds appropriated under the heading “Department of Energy—Clean Coal Technology,” up to a total amount of $2,500,000,000 for commercial demonstration of clean coal technology, or similar projects funded through appropriations for the Environmental Protection Agency. The federal contribution for a qualifying project shall be at least 20 percent of the total cost of the demonstration project.

  • Source-image receptor distance means the distance from the source to the center of the input surface of the image receptor.

  • Total tetrahydrocannabinol means the sum of the percentage by weight of tetrahydrocannabinolic acid multiplied by eight hundred seventy-seven thousandths plus the percentage of weight of tetrahydrocannabinol.

  • The Contract Price/Project Cost means the price payable to the Vendor under the Contract for the full and proper performance of its contractual obligations.

  • Treatability study means a study in which a hazardous waste is subjected to a treatment process to determine: (1) Whether the waste is amenable to the treatment process, (2) what pretreatment (if any) is required, (3) the optimal process conditions needed to achieve the desired treatment, (4) the efficiency of a treatment process for a specific waste or wastes, or (5) the characteristics and volumes of residuals from a particular treatment process. Also included in this definition for the purpose of the § 261.4 (e) and (f) exemptions are liner compatibility, corrosion, and other material compatibility studies and toxicological and health effects studies. A “treatability study” is not a means to commercially treat or dispose of hazardous waste.

  • Planned development means a real property development other than a community apartment project, a condominium project, or a stock cooperative, having either or both of the following features: