PoC Trial definition

PoC Trial means, with respect to a Collaboration Program, the first phase 2a Clinical Study in human patients with a pharmacokinetic or target reduction endpoint or other therapeutic or physiological endpoint.

PoC Trial means, with respect to any Collaboration Compound, a [***] Clinical Trial or a [***] Clinical Trial of such Collaboration Compound that is reasonably designed to demonstrate successfully the PoC Compound Criteria. For clarity, the PoC Trial is intended only to demonstrate the safety, and to provide preliminary evidence of activity, of a particular Collaboration Compound, and is not intended to be a pivotal trial or to otherwise provide data sufficient to support Regulatory Approvals.

PoC Trial means the first human in-patient study designed to provide evidence of efficacy, safety and tolerability of SPC-3649 or an SPC-3649 Product.

Examples of PoC Trial in a sentence

• Except as expressly set out to the contrary in, this clause 6, these Terms and the Agreement, the terms and conditions of these Terms and the Agreement, fully apply in respect of a POC Trial.

• Cyferd may modify or terminate the Customer’s use of the Cyferd Product (or any part of it including any App(s) and Feature(s)) and/or any of the applicable Services for the purposes of a POC Trial at any time and for any reason in Cyferd’s sole discretion, without liability to the Customer.

• For the avoidance of doubt neither a POC Trial nor a Purchased Item can be a No Charge Product.

• To the maximum extent permitted by applicable law, Cyferd disclaims all obligations or liabilities with respect to the Customer’s use of the Cyferd Product (including any App(s) and Feature(s)) and the applicable Services for the purposes of a POC Trial including any warranty and indemnity obligations.

More Definitions of PoC Trial

PoC Trial means (a) with respect to the AR Mutant Program, the AR Mutant POC Trial and (b) with respect to the NIK Program, the NIK POC Trial.

PoC Trial means, with respect to a Program, the first human in-patient study designed to provide evidence of efficacy, safety and tolerability of a Collaboration Compound within such Program, which if conducted by Regulus, shall be consistent with the [...***...]agreed upon by the Parties and the PoC Financial Cap, subject to Section 3.5.5. For purposes of clarity, the PoC Trial is intended only to demonstrate the [...***...] of a particular Development Candidate, and is not intended to be a [...***...], or intended to otherwise provide data [...***...].

PoC Trial means a ‘proof of concept’ trial being time-bound access to a dedicated Cyferd operated tenancy for the purposes of evaluating the Cyferd Product’s features and functionality

PoC Trial means the first proof of concept [***] that meets the POC Trial Criteria.

PoC Trial means a Phase II Study of the Compound tipifarnib in HRAS mutant patients in the Field, as more fully described in the Development Plan.

PoC Trial means with respect to any Research Program Development Candidate, NP201 Development Candidate or Tail Compound, as applicable, the first human clinical trial that either: (i) is reasonably designed to; and/or (ii) actually does, establish POC in humans. For clarity, the concept of a “Proof of Concept Trial” is intended only to identify the time point at which the POC of a particular Research Program Development Candidate, NP201 Development Candidate or Tail Compound has been demonstrated, and a “Proof of Concept Trial” is not [*]

PoC Trial means a Phase II Study of the Compound tipifarnib in HRAS mutant patients in the Field, as more fully described in the Development