HER2 definition

HER2 means v-xxx-b2 erythroblastic leukemia viral oncogene homolog having a Genbank ID number of 2064 and a protein sequence as shown in Exhibit 1.
Sample 1Sample 2
HER2 means the Target that is the protein known as human epidermal growth factor receptor 2.
Sample 1Sample 2
HER2 means the [***]
Sample 1Sample 2

Examples of HER2 in a sentence

  • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

  • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/ neu oncogene.

  • Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer.

  • HER-2 testing in breast cancer using parallel tissue-based methods.

  • Agreement between chromogenic in situ hybridization (CISH) and FISH in the determination of HER2 status in breast cancer.

  • Expression of C-KIT and HER-2 tyrosine kinase receptors in poor-prognosis breast cancer.

  • Assessment of a HER2 scoring system for gastric cancer: results from a validation study.

  • Topoisomerase Iiα (topoII) and HER2 amplifiation in breast cancers and response to preoperative doxorubicin chemotherapy.

  • US incidence of breast cancer subtypes defined by joint hormone receptor and HER2 status.

  • Chromogenic in situ hybridization: A novel approach to a practical and sensitive method for the detection of HER2 oncogene in archival human breast carcinoma.


More Definitions of HER2

HER2 means (a) receptor tyrosine-protein kinase erbB-2, and (b) any naturally occurring variants thereof, in each case including any isoforms, polymorphisms, variants, and truncated forms, and in each case to the extent such variant, isoform, polymorphism, variant and truncated form are produced from an allele of the same gene.
Sample 1
HER2 means human epidermal growth factor receptor 2, also known as CD340 or Her-2/neu encoded by the ERBB2 gene.
Sample 1

Related to HER2

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  • genocide means any of the following acts committed with intent to destroy, in whole or in part, a national, ethnical, racial or religious group, as such:

  • Biological Samples means any physical samples obtained from Study Participants in accordance with the Protocol for the purposes of the Study.

  • Precursor means any chemical reactant which takes part at any stage in the production by whatever method of a toxic chemical. This includes any key component of a binary or multicomponent chemical system.

  • Nicotine means nicotinic alkaloids;

  • Prosthesis means an artificial substitute for a missing body part.

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  • Cannabinoid edible means food or potable liquid into which a cannabinoid concentrate, cannabinoid extract or dried marijuana leaves or flowers have been incorporated.

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  • Enteral means within or by way of the intestine.

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  • Infection means the entry and development or multiplication of an infectious agent in the body of humans and animals that may constitute a public health risk;

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