Recombinant DNA definition

Recombinant DNA means genetic material produced by the combining of DNA molecules from different organisms;

Recombinant DNA means the transfer of genes, regulatory sequences, or nucleic acid between hosts by the use of vectors or laboratory manipulations and includes the insertion, excision, duplication, inactivation, or relocation of specific genes, regulatory sequences, or sections of nucleic acid. This term does not apply to a material or an organism developed exclusively through traditional methods of breeding, hybridization, or nondirected mutagenesis.

Recombinant DNA means the DNA sequences encoding any SMIP including, without limitation, any DNA plasmid expression construct encoding any such SMIP.

Examples of Recombinant DNA in a sentence

• Recombinant DNA is defined as (i) molecules that are constructed outside living cells by joining natural or synthetic DNA segments to DNA molecules that can replicate in living cells or (ii) molecules that result from the replication of those described in (i) above.

• This BAA may contain topics that have been identified by the Program Manager as research or activities involving Human/Animal Subjects and/or Recombinant DNA.

• Research Involving Recombinant DNA Molecules Any recipient performing research involving recombinant DNA molecules and/or organisms and viruses containing recombinant DNA molecules shall comply with the National Institutes of Health Guidelines for Research Involving Recombinant DNA Molecules, dated January 2011, as amended.

• See the NIH Guidelines for Research Involving Recombinant DNA Molecules.

• Use of Recombinant DNA or Synthetic Nucleic Acid Molecules: Proposals which call for experiments using recombinant or synthetic nucleic acid molecules must include documentation of compliance with NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines), approval of the Institutional Biosafety Committee (IBC), and copies of the DHHS Approval of the IBC letter.

• BIOMEDICAL FACILITY: Any facility engaged in the use of materials such as (but not limited to) Recombinant DNA, live animals for testing, the use of potentially infectious cell lines, or infectious material, including biomedical facilities defined by the National Institute of Health as a Biolevel-1 (BL-1) or Biolevel-2 (BL-2) facility.

• If a clinical protocol has been reviewed by an institutional biosafety committee (IBC) or the NIH Recombinant DNA Advisory Committee (RAC), the Contractor must provide information about the initial and ongoing review and approval, if any.

• Recombinant DNA technology and drug discovery rDNA technology, hybridoma technology, New pharmaceuticals derived from biotechnology; Oligonucleotide therapy.

• In the event that the Cooperator has not established the necessary biosafety committee, a request for guidance or assistance may be made to the USDA Recombinant DNA Research Officer.

• Research Involving Recombinant DNA Molecules - The Contractor and its respective principle investigators or research administrators must comply with the most recent Public Health Service Guidelines for Research Involving Recombinant DNA Molecules published at Federal Register 46266 or such later revision of those guidelines as may be published in the Federal Register as well as current NIH Guidelines for Research Involving Recombinant DNA Molecules.

More Definitions of Recombinant DNA

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Recombinant DNA means genetic material produced by the combining of DNA molecules

Recombinant DNA means molecules that consist of different segments of deoxyribonucleic acid which have been joined together in cell-free systems and which have the capacity to infect and replicate in some host cell, either autonomously or as an integrated part of the host's genome.

Recombinant DNA means molecules that are constructed outside living cells by joining natural or synthetic deoxyribonucleic acid (DNA) segments to DNA molecules that can replicate in a living cell, or molecules that result from the replication of those described herein;