Project Element # 1 – Generation of Low-Level Mixed Waste Sample Clauses

Project Element # 1 – Generation of Low-Level Mixed Waste. The generation of LLMW is an unavoidable result of pharmaceutical research which involves the study the safety of drug compounds in the human body, given the FDA’s requirement of the use of radioactive tracers in such research. During these studies, carbon-14- and tritium- labeled compounds are synthesized for use in the development of potential new therapeutic compounds. These syntheses generate millicurie (mCi) to Xxxxx (Ci) (see Appendix F for explanation of units of measurement) quantities of LLMW test samples containing a wide variety of organic materials which are classified as hazardous wastes under RCRA. These consist of contaminated aqueous mixtures and various organic solvents, intermediates, and reagents used in the synthesis and purification of radiolabeled samples. The organic components include hydrocarbons, halocarbons, acetonitrile, alcohols, ethers, and aromatic compounds. A single preparation involves volumes ranging from less than 50 mL to several liters.
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