Unoprostone definition

Unoprostone. (also known by the USAN name of Unoprostone isopropyl) is the composition of matter defined chemically as isopropyl [*] as further described in Exhibit A, and its salts, metabolites, as well as any active pro-drugs, isomers, tautomers, hydrates, chelates, complexes and polymorphs and all other pharmaceutically acceptable modifications as may be projected in the public domain as motivation to an medicinal chemistry expert in the drug development field.
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Unoprostone means the compound described in more detail in Appendix A.
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Unoprostone means the compound also known by the USAN name of unoprostone isopropyl, which is the composition of matter defined chemically as […***…], including all […***…], as well as any […***…] and […***…] , in any form, […***…] and […***…], and for any use in any human indication.
Sample 1

Examples of Unoprostone in a sentence

  • On May 6, 2015, Sucampo AG and the Company executed a transfer and termination agreement to effectuate the return of all licenses for Unoprostone to the Company.

  • These licenses had provided Sucampo AG with exclusive development and commercialization rights to Unoprostone globally except for Japan, the People's Republic of China, Taiwan and Korea.

  • BK Channel Activation Unoprostone Isopropyl Mechanism of Action Voltage-gated BK-type potassium channels can change a cell’s net internal charge, and thus it’s behavior behavior.

  • On April 23, 2009, the Company entered into a licensing agreement whereby the Company granted to Sucampo AG the exclusive rights to develop, manufacture, commercialize, and sell Unoprostone in North America and Canada, for all indications including glaucoma and ocular hypertension.

  • Sucampo shall use commercially reasonable efforts to assist R-Tech in the transition of the Unoprostone after the Effective Date.

  • Exhibit B CONFIDENTIAL Unoprostone NDA Transfer/IP and Data Sharing Agreement Exhibit B [Separately filed with the Securities and Exchange Commission] [*] = Certain confidential information contained in this document, marked by brackets, is filed with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

  • RTU represents and warrants that there is no threatened, pending or settled litigation with respect to the Unoprostone or the Licensed Product or that may affect in any way RTU’s ability to grant the rights and licenses granted by RTU under this Agreement.

  • Unless otherwise agreed to by the Parties and set forth in writing, RTU and SPA hereby agree that the terms of this Agreement and all ancillary agreements hereto (including, without limitation, the Unoprostone Supply Agreement attached hereto) shall fully define any and all consideration, compensation and benefits, monetary or otherwise, to be paid, granted or delivered by each Party to the other in connection with the transactions contemplated herein.

  • Unoprostone Isopropyl and Metabolite M1 Activate BK Channels & Prevent ET-1-Induced [Ca2+]i Increases in Human Trabecular Meshwork and Smooth Muscle.

  • Exhibit D CONFIDENTIAL Unoprostone NDA Transfer/IP and Data Sharing Agreement Exhibit D List of Trademarks RESCULA Country Application No. Category Application Date Registration No. USA 77/470526 Class 5 2008.5.9 Canada 806022 Class 5 1996.3.4 806022 [*] = Certain confidential information contained in this document, marked by brackets, is filed with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

Related to Unoprostone

  • Cannabinoid means any of the chemical compounds that are the active constituents of marijuana.

  • Cannabis products means cannabis that has undergone a process whereby the plant material has been transformed into a concentrate, including, but not limited to, concentrated cannabis, or an edible or topical product containing cannabis or concentrated cannabis and other ingredients.

  • Cannabis means all parts of the plant Cannabis sativa Linnaeus, Cannabis indica, or Cannabis ruderalis, whether growing or not; the seeds thereof; the resin, whether crude or purified, extracted from any part of the plant; and every compound, manufacture, salt, derivative, mixture, or preparation of the plant, its seeds, or resin. “Cannabis” also means the separated resin, whether crude or purified, obtained from cannabis. “Cannabis” does not include the mature stalks of the plant, fiber produced from the stalks, oil or cake made from the seeds of the plant, any other compound, manufacture, salt, derivative, mixture, or preparation of the mature stalks (except the resin extracted therefrom), fiber, oil, or cake, or the sterilized seed of the plant which is incapable of germination. For the purpose of this division, “cannabis” does not mean “industrial hemp” as defined by Section 11018.5 of the Health and Safety Code.

  • Radiopharmaceutical means any drug that exhibits spontaneous disintegration of unstable nuclei with the emission of nuclear particles or photons and includes any non-radioactive reagent kit or radionuclide generator that is intended to be used in the preparation of any such substance, but does not include drugs such as carbon-containing compounds or potassium-containing salts that include trace quantities of naturally occurring radionuclides. The term also includes any biological product that is labeled with a radionuclide or intended solely to be labeled with a radionuclide.

  • Precursor means any chemical reactant which takes part at any stage in the production by whatever method of a toxic chemical. This includes any key component of a binary or multicomponent chemical system.

  • Parenteral means a method of drug delivery injected into body tissues but not via the gastrointestinal tract.

  • Cannabis product means cannabis that has undergone a process whereby the plant material has been transformed into a concentrate, including, but not limited to, concentrated cannabis, or an edible or topical product containing cannabis or concentrated cannabis and other ingredients.

  • API means American Petroleum Institute.

  • coronavirus means severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2);

  • Prosthesis means an artificial substitute for a missing body part.