Factor Xa definition

Factor Xa means coagulation factor Xa. Its IUBMB designation is EC 3.4.21.6, and it is also referred to as prothrombase or activated Stuart-Prower factor.
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Examples of Factor Xa in a sentence

  • Portola Pharmaceuticals Licenses Oral Factor Xa Inhibitor, a Potential Chronic Anticoagulant SOUTH SAN FRANCISCO, Calif., Aug.

  • The Factor Xa program is a strong complement to the programs currently under development within Portola.

  • Under the terms of the agreement, Portola has licensed exclusive rights to develop, market and commercialize Factor Xa inhibitors worldwide.

  • Given orally once a day, the lead compound is a small molecule that acts directly on the blood coagulation enzyme Factor Xa, a clinically validated target involved in the generation of thrombin, the principal mediator of excessive clotting resulting in thrombosis.

  • Andexanet alfa is in development as a potential antidote for Factor Xa inhibitors.

  • Corvas shall provide staffing for the Factor Xa Research Program at a level of [...***...] FTEs [...***...] during the New Extension Period.

  • The Parties acknowledge that Portola intends to develop Andexanet Alfa as a universal reversal agent for all commercially available Factor Xa inhibitors.

  • The Company is advancing three programs, including betrixaban, an oral, once-daily Factor Xa inhibitor; AndexXaTM (andexanet alfa), a recombinant protein designed to reverse the anticoagulant effect in patients treated with an oral or injectable Factor Xa inhibitor; and cerdulatinib, a Syk/JAK inhibitor in development to treat hematologic cancers.

  • Alexion also has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D) as well as the first and only approved Factor Xa inhibitor reversal agent.

  • Aventis currently has 94 new chemical entities and vaccines in development Aventis has moved four compounds in to late-stage development: 100,907, a compound targeted to improve the quality of sleep; teriflunomide for the treatment of multiple sclerosis; a direct Factor Xa inhibitor (0673) for the treatment of acute coronary syndromes; and a new taxoid (109,881) for the treatment of cancer.

Related to Factor Xa

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  • Target Population means persons with low incomes who have one or more disabilities, including mental illness, HIV or AIDS, substance abuse, or other chronic health condition, or individuals eligible for services provided pursuant to the Lanterman Developmental Disabilities Services Act (Division 4.5 (commencing with Section 4500) of the Welfare and Institutions Code) and may include, among other populations, adults, emancipated minors, families with children, elderly persons, young adults aging out of the foster care system, individuals exiting from institutional settings, veterans, and homeless people.

  • QAP shall have the meaning set forth in Clause 11.2;

  • COVID-19 Measures means any quarantine, “shelter in place,” “stay at home,” workforce reduction, social distancing, shut down, closure, sequester or any other Law, directive, guidelines or recommendations by any Governmental Authority (including the Centers for Disease Control and the World Health Organization) in each case in connection with, related to or in response to COVID-19, including the Coronavirus Aid, Relief, and Economic Security Act (CARES) or any changes thereto.

  • Capitation rate means the fee the department pays monthly to a participating health or dental plan for each enrollee for the provision of covered medical or dental services whether or not the enrollee received services during the month for which the fee is intended.

  • Program Plan means the tobacco settlement program plan dated February 14, 2001, including exhibits to the program plan, submitted by the authority to the legislative council and the executive council, to provide the state with a secure and stable source of funding for the purposes designated by section 12E.3A and other provisions of this chapter.

  • Indigenous Peoples Plan or “IPP” means any of the plans prepared and carried out following the requirements of the Indigenous Peoples Planning Framework.

  • Batch number means a unique numeric or alphanumeric identifier assigned prior to any testing to allow for inventory tracking and traceability.

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  • Deferral Percentage means the percentage (which, unless the Administrator, in his or her sole discretion, determines otherwise, shall be in whole percentage increments and not more than 90%) specified by the Participant to be the percentage of each payment of Compensation he or she wishes to defer under the Plan.

  • Key Performance Indicator means a measure that captures the performance of a critical variable to expand and improve community-based corrections programs to promote offender success, ensure accountability, enhance public safety, and reduce recidivism.

  • Lot or batch number means an identifying number assigned by the enterprise to a designated group of items, usually referred to as either a lot or a batch, all of which were manufactured under identical conditions.

  • Matrix (1 2 8 9) means a substantially continuous phase that fills the space between particles, whiskers or fibres.