CFTR definition

CFTR means a CF transmembrane conductance regulator protein which has the biological effect of transporting molecules across human cellular membranes.
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CFTR means cystic fibrosis transmembrane conductance regulator.
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CFTR means CF transmembrane conductance regulator.
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Examples of CFTR in a sentence

  • A CFTR potentiator in patients with cystic fibrosis and the G551D mutation.

  • Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770.

  • A functional CFTR assay using primary cystic fibrosis intestinal organoids.

  • If two mutations are not identified, CFTR full gene sequencing (CPT 81223) is covered.

  • CFTR mutation detection by multiplex heteroduplex (mHET) analysis on MDE gel.

  • Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis.

  • Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.

  • Lung disease associated with the IVS8 5T allele of the CFTR gene.

  • Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients.

  • Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.


More Definitions of CFTR

CFTR means a CF transmembrane conductance regulator protein which has the biological effect of transporting molecules across human cellular membranes. PORTIONS OF THIS EXHIBIT WERE OMITTED AND HAVE BEEN FILED SEPARATELY WITH THE SECRETARY OF THE COMMISSION PURSUANT TO THE COMPANY'S APPLICATION REQUESTING CONFIDENTIAL TREATMENT UNDER RULE 406 OF THE SECURITIES ACT; [*] DENOTES OMISSIONS.
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CFTR means the human Cystic Fibrosis Transmembrane conductance Regulator protein.
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CFTR means a CF transmembrane conductance regulator protein which has the biological effect of transporting molecules across
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CFTR means the Cystic Fibrosis Transmembrane Conductance Regulator gene. The Test System is used to detect and identify this gene’s mutations in newborn screenings.
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