Krystal Biotech, Inc. Sample Contracts

KRYSTAL BIOTECH, INC. Common Stock (par value $0.00001 per share) SALES AGREEMENT
Sales Agreement • May 8th, 2023 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • New York

Krystal Biotech, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows:

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Krystal Biotech, Inc. 1,923,077 Shares Common Stock ($0.00001 par value) Underwriting Agreement
Krystal Biotech, Inc. • February 5th, 2021 • Biological products, (no disgnostic substances) • New York

Krystal Biotech, Inc., a corporation organized under the laws of Delaware (the “Issuer”), proposes to issue and sell to the several underwriters named in Schedule I hereto (the “Underwriters”), for whom Goldman Sachs & Co. LLC (“Goldman Sachs”), Cowen and Company, LLC (“Cowen”) and Evercore Group L.L.C. (“Evercore”) are acting as representatives (the “Representatives”), 1,923,077 shares of common stock, $0.00001 par value per share (“Common Stock”) of the Issuer (said shares to be issued and sold by the Issuer being hereinafter called the “Underwritten Securities”). The Issuer also proposes to grant to the Underwriters an option to purchase 288,461 additional shares of Common Stock to cover over-allotments, if any (the “Option Securities;” the Option Securities, together with the Underwritten Securities, hereinafter called the “Securities”). To the extent there are no additional Underwriters listed on Schedule I other than you, the term Representatives as used herein shall mean you, as

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • May 22nd, 2023 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • New York

This REGISTRATION RIGHTS AGREEMENT (this “Agreement”) is made and entered into as of May 21, 2023, by and among Krystal Biotech Inc., a Delaware corporation (the “Company”), and the “Investors” named in that certain Securities Purchase Agreement by and among the Company and the Investors, dated as of May 21, 2023 (the “Purchase Agreement”). Capitalized terms used herein have the respective meanings ascribed thereto in the Purchase Agreement unless otherwise defined herein.

FORM OF INDEMNIFICATION AGREEMENT (DIRECTORS)
Indemnification Agreement • September 14th, 2017 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • Delaware

This Indemnification Agreement (Directors) (this “Agreement”) is made and entered into on [ ], by and between Krystal Biotech, Inc., a Delaware corporation with a principal business address of 2100 Wharton Street, Suite 701, Pittsburg, PA 15203 (the “Company”), and [ ], an individual resident of the State of [ ] with a residential address as set forth on the signature page hereto (“Indemnitee”), to be effective as of [ ], 20[ ] (the “Effective Date”).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • May 22nd, 2023 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • New York

This SECURITIES PURCHASE AGREEMENT (this “Agreement”) is made and entered into as of May 21, 2023, by and among Krystal Biotech, Inc., a Delaware corporation (the “Company”), and the Investors identified on Exhibit A attached hereto (each an “Investor” and collectively the “Investors”).

KRYSTAL BIOTECH, INC. STOCK PURCHASE AGREEMENT
Stock Purchase Agreement • August 17th, 2018 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • New York

This Stock Purchase Agreement (the “Agreement”) is made as of August 16, 2018 (the “Effective Date”), by and among Krystal Biotech, Inc., a Delaware corporation (the “Company”), and the purchasers whose names and addresses are set forth on the signature pages hereof (each, a “Purchaser” and, collectively, the “Purchasers”).

EMPLOYMENT AGREEMENT
Employment Agreement • September 7th, 2017 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • California

This Employment Agreement (“the Agreement”), dated July 1, 2017, is between Krystal Biotech, Inc., a Delaware corporation] (the “Company”) and Krish S. Krishnan, (“Employee”).

Contract
Lease Agreement • March 1st, 2021 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)
Contract
Employment Agreement • March 1st, 2021 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • Pennsylvania
Contract
Lease Agreement • March 1st, 2021 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)
Contract
Lease Agreement • March 1st, 2021 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)
EMPLOYMENT AGREEMENT
Employment Agreement • September 7th, 2017 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • Pennsylvania

This Employment Agreement (“the Agreement”), dated May 1, 2017, is between Krystal Biotech, Inc., a Delaware corporation] (the “Company”) and POOJA AGARWAL, (“Employee”), and reflects the Company’s and Employee’s desire to establish a full employment relationship following Employee’s service to Krystal Biotech, LLC, a predecessor of the Company.

INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • August 21st, 2017 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • Delaware

THIS INVESTORS’ RIGHTS AGREEMENT (this “Agreement”) is made as of August 7, 2017 by and among KRYSTAL BIOTECH, INC., a Delaware corporation (the “Company”) the investors listed on Schedule A hereto (each an “Investor” and collectively the “Investors”) and those persons listed on Schedule B hereto (each, a “Founder”, and collectively, the “Founders”).

Contract
Lease Agreement • February 28th, 2022 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)
Contract
Lease Agreement • March 1st, 2021 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)
Contract
Lease Agreement • February 28th, 2022 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)
Krystal Biotech, Inc. 2,666,667 Shares Common Stock ($0.00001 par value) Underwriting Agreement
Krystal Biotech, Inc. • December 3rd, 2021 • Biological products, (no disgnostic substances) • New York

Krystal Biotech, Inc., a corporation organized under the laws of Delaware (the “Issuer”), proposes to issue and sell to the several underwriters named in Schedule I hereto (the “Underwriters”), for whom Goldman Sachs & Co. LLC (“Goldman Sachs”), BofA Securities, Inc., (“BofA”),Cowen and Company, LLC (“Cowen”) and William Blair & Company, L.L.C. (“William Blair”), are acting as representatives (the “Representatives”), 2,666,667 shares of common stock, $0.00001 par value per share (“Common Stock”) of the Issuer (said shares to be issued and sold by the Issuer being hereinafter called the “Underwritten Securities”). The Issuer and the entities named in Schedule IV hereto (each a “Selling Stockholder” and together, the “Selling Stockholders”) also propose to grant to the Underwriters an option to purchase up to 200,000 additional shares of Common Stock set forth in Schedule II (the “Issuer Option Securities”) and up to 200,000

Contract
Lease Agreement • February 28th, 2022 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)
SECOND AMENDMENT TO LEASE AGREEMENT
Lease Agreement • September 7th, 2017 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)

THIS SECOND AMENDMENT TO LEASE AGREEMENT (the “Second Amendment”) is made as of the 27 day of February, 2017, by and between Wharton Lender Associates, L.P., (“Landlord”), and Krystal Biotech LLC, (“Tenant”).

LEASE BY AND BETWEEN WHARTON LENDER ASSOCIATES, LP, LANDLORD AND KRYSTAL BIOTECH LLC, TENANT OF
Lease • September 7th, 2017 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • Pennsylvania
EMPLOYMENT AGREEMENT
Employment Agreement • May 4th, 2020 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • Pennsylvania

This Employment Agreement (“the Agreement”), dated December 5, 2019, is between Krystal Biotech, Inc., a Delaware corporation (the “Company”) and Jennifer Chien (“Employee”) and reflects the Company’s and Employee’s desire to establish a full employment relationship.

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Contract
Lease Agreement • March 1st, 2021 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances)
EMPLOYMENT AGREEMENT
Employment Agreement • March 12th, 2018 • Krystal Biotech, Inc. • Biological products, (no disgnostic substances) • California

This Employment Agreement (“the Agreement”), dated March 8 2018, is between Krystal Biotech, Inc., a Delaware corporation (the “Company”) and Antony Riley, (“Employee”) and reflects the company’s and Employee’s desire to establish a full employment relationship.

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