The Inverse Gaussian Model Sample Clauses

The Inverse Gaussian Model. Two hypothetical time paths of depression (one solid and one dashed) showing actual and linear smoothed depression scores. The participant’s depression score under the inverse Gaussian model evolves as Brownian motion with a trend but with random local changes. Reaching the threshold for remission is determined by the patient’s initial severity or baseline position and the rate of recovery or progression towards or away from remission. If larger values of 𝑋 correspond to a state of worse depression, a patient is in the GENDEP study as their depression status is above a clinical threshold. Following the path from randomisation, the patient would be determined to be in remission when their level falls below the threshold, 𝐴, Defined here to be a score of 10 or less on the MADRS (Xxxxxx, Xxxx et al. 2002, Xxxxxx, Himmerich et al. 2003). The time it takes for 𝑋(𝑡) to move from randomisation, 𝑡0, to remission, 𝑡𝐴, is the individual’s time to remission. Since 𝑋(𝑡) is a stochastic process, the individual’s time to remission will be a random variable with characteristics dependent on the statistical properties of 𝑋(𝑡). The stochastic process is comparable to a physical diffusion process. As time passes, the patient’s depression level fluctuates randomly about a trend, shown by the straight line, and at some point the patient’s depression reaches the threshold and they are deemed to be in remission. There are many factors which may influence the depression level to deviate from its expected path which could be compared to the movement of a molecule colliding with other molecules. Therefore, this process is Brownian motion with drift. Formally, it is characterised as a Wiener diffusion process that exhibits drift from an initial level at randomisation, towards an absorbing barrier at level 𝐴. The first passage time to the absorbing barrier follows an IG distribution (Cox and Xxxxxx 1977). For 𝑋(𝑡) to be a Wiener process it must satisfy the following conditions (Xxxxxxxx 1975):
AutoNDA by SimpleDocs

Related to The Inverse Gaussian Model

  • Placement of EPP probes Probes for measuring EPP parameters shall be placed inside or close to Registrars points of access to the Internet across the different geographic regions; care shall be taken not to deploy probes behind high propagation-­‐delay links, such as satellite links.

  • DUŠEVNÍ VLASTNICTVÍ The Institution acknowledges and agrees that the Sponsor shall have exclusive ownership rights to all Poskytovatel uznává a souhlasí, že Zadavatel bude mít výhradní vlastnická práva ke všem Study Data, improvements, developments, discoveries, inventions, work, know-how and other rights (whether or not patentable), created, developed, and/or reduced to practice as a result of or in connection with the conduct of the Study and/or the use of the Study Drug or the Confidential Information, together with all intellectual property rights relating thereto (“Intellectual Property”). The Institution shall promptly disclose in writing to PSI and the Sponsor all Intellectual Property made by the Institution, the Investigator and/or the Study Personnel. At the Sponsor's request, the Institution shall cause all rights titles and interests in and to any such Intellectual Property to be assigned to the Sponsor without additional compensation and provide reasonable assistance to obtain patents, including causing the execution of any invention assignment or other documents. Studijním údajům, vylepšením, na vývoj, k objevům, vynálezům, dílům, know-how a dalším právům (ať už patentovatelným či nikoli), vytvořeným, vyvinutým, a/nebo uvedeným do praxe v důsledku nebo v souvislosti s prováděním Studie, a/nebo používáním Studijního léku nebo Důvěrných informací společně s právy duševního vlastnictví s nimi souvisejícími (dále jen „Duševní vlastnictví“). Poskytovatel bude neprodleně písemně informovat PSI a Zadavatele o veškerém Duševním vlastnictví vytvořeném Poskytovatelem, Hlavním zkoušejícím a/nebo Studijním personálem. Na žádost Zadavatele zajistí Poskytovatel převod veškerých práv a zájmů týkajících se Duševního vlastnictví na Zadavatele bez další odměny a poskytne přiměřenou součinnost k získání patentu včetně zajištění podpisu dokumentů k převodu objevu nebo jiných dokumentů.

  • XxxXxxxx Principles - Northern Ireland The provisions of San Francisco Administrative Code §12F are incorporated herein by this reference and made part of this Agreement. By signing this Agreement, Contractor confirms that Contractor has read and understood that the City urges companies doing business in Northern Ireland to resolve employment inequities and to abide by the XxxXxxxx Principles, and urges San Francisco companies to do business with corporations that abide by the XxxXxxxx Principles.

  • Dienste Und Materialien Von Drittanbietern (a) Die Apple-Software gewährt möglicherweise Zugang zu(m) iTunes Store, App Store, Apple Books, Game Center, iCloud, Karten von Apple und zu anderen Diensten und Websites von Apple und Drittanbietern (gemeinsam und einzeln als „Dienste“ bezeichnet). Solche Dienste sind möglicherweise nicht in xxxxx Sprachen oder in xxxxx Ländern verfügbar. Die Nutzung dieser Dienste erfordert Internetzugriff und die Nutzung bestimmter Dienste erfordert möglicherweise eine Apple-ID, setzt möglicherweise dein Einverständnis mit zusätzlichen Servicebedingungen voraus und unterliegt unter Umständen zusätzlichen Gebühren. Indem du diese Software zusammen mit einer Apple-ID oder einem anderen Apple-Dienst verwendest, erklärst du dein Einverständnis mit den anwendbaren Servicebedingungen für diesen Dienst, z. B. den neuesten Apple Media Services-Bedingungen für das Land, in dem du auf diese Services zugreifst, die du über die Webseite xxxxx://xxx.xxxxx.xxx/legal/ internet-services/itunes/ anzeigen und nachlesen kannst

  • Eindgebruikers binnen de Amerikaanse overheid De Apple software en de bijbehorende documentatie zijn “Commercial Items”, zoals omschreven in 48 C.F.R. §2.101, en bestaan uit “Commercial Computer Software” en “Commercial Computer Software Documentation”, zoals beschreven in 48 C.F.R. §12.212 of 48 C.F.R. §227.7202, afhankelijk xxx xxxxx paragraaf van toepassing is. Overeenkomstig 48 C.F.R. §12.212 of 48 C.F.R. §227.7202-1 tot en met 227.7202-4, afhankelijk xxx xxxxx paragraaf van toepassing is, xxxxxx de “Commercial Computer Software” en “Commercial Computer Software Documentation” aan eindgebruikers binnen de Amerikaanse overheid (a) alleen als “Commercial Items” in licentie gegeven en (b) alleen met de rechten die xxxxxx verleend aan alle andere eindgebruikers conform de voorwaarden die hierin xxxxxx genoemd. Ongepubliceerd: rechten voorbehouden krachtens de auteursrechtwetgeving van de Verenigde Staten.

  • SBC-12STATE 47.1.1 The terms contained in this Agreement and any Appendices, Attachments, Exhibits, Schedules, and Addenda constitute the entire agreement between the Parties with respect to the subject matter hereof, superseding all prior understandings, proposals and other communications, oral or written between the Parties during the negotiations of this Agreement and through the execution and/or Effective Date of this Agreement. This Agreement shall not operate as or constitute a novation of any agreement or contract between the Parties that predates the execution and/or Effective Date of this Agreement.

  • Exclusión de garantías A. Si usted es un consumidor particular (una persona que utiliza el Software Apple fuera de su oficio, negocio o profesión), es posible que disponga de derechos legales en su país de residencia que puedan impedir que las siguientes limitaciones le xxxx aplicables, en cuyo caso no serán de aplicación para usted. Para obtener más información acerca de sus derechos debería consultar a una organización de consumo local.

  • Vlastnictví Zdravotnické zařízení si ponechá a bude uchovávat Zdravotní záznamy. Zdravotnické zařízení a Zkoušející převedou na Zadavatele veškerá svá práva, nároky a tituly, včetně práv duševního vlastnictví k Důvěrným informacím (ve smyslu níže uvedeném) a k jakýmkoli jiným Studijním datům a údajům.

  • Geological and Archeological Specimens If, during the execution of the Work, the Contractor, any Subcontractor, or any servant, employee, or agent of either should uncover any valuable material or materials, such as, but not limited to, treasure trove, geological specimens, archival material, archeological specimens, or ore, the Contractor acknowledges that title to the foregoing is vested in the Owner. The Contractor shall notify the Owner upon the discovery of any of the foregoing, shall take reasonable steps to safeguard it, and seek further instruction from the Design Professional. Any additional cost incurred by the Contractor shall be addressed under the provision for changed conditions. The Contractor agrees that the Geological and Water Resources Division and the Historic Preservation Division of the Georgia Department of Natural Resources may inspect the Work at reasonable times.

  • Description of Vendor Entity and Vendor's Goods & Services If awarded, this description of Vendor and Vendor's goods and services will appear on the TIPS website for customer/public viewing. Full service mechanical and electrical contractors offering professional solutions and services in HVAC, Refrigeration, Piping, Plumbing, Electrical, Controls and Engineering. Primary Contact Name Please identify the individual who will be primarily responsible for all TIPS matters and inquiries for the duration of the contract. Xxxx Xxxxx Primary Contact Title Primary Contact Title Project Manager Primary Contact Email Please enter a valid email address that will definitely reach the Primary Contact. xxxxxx@xxxxxxxxxxxxxx.xxx Primary Contact Phone Numbers only, no symbols or spaces (Ex. 8668398477). The system will auto-populate your entry with commas once submitted which is appropriate and expected (Ex. 8,668,398,477). Please provide the accurate and current phone number where the individual who will be primarily responsible for all TIPS matters and inquiries for the duration of the contract can be reached directly. 0000000000 Primary Contact Fax Numbers only, no symbols or spaces (Ex. 8668398477). The system will auto-populate your entry with commas once submitted which is appropriate and expected (Ex. 8,668,398,477). 1 0 0000000000 Primary Contact Mobile Numbers only, no symbols or spaces (Ex. 8668398477). The system will auto-populate your entry with commas once submitted which is appropriate and expected (Ex. 8,668,398,477). 1 0000000000 Secondary Contact Name Please identify the individual who will be secondarily responsible for all TIPS matters and inquiries for the duration of the contract. Xxxx Xxxxx Secondary Contact Title Secondary Contact Title

Time is Money Join Law Insider Premium to draft better contracts faster.