Common use of Advanced Training Clause in Contracts

Advanced Training. ƒ The STYL’one Nano is a sophisticated compression data acquisition tool, and to ensure that the full capability of the system can be realized, our teams of experts can provide advanced training to convey best practices for experimental design, data acquisition, data analysis and interpretation of the results. ƒ Characterize APIs & Excipients ƒ Formulation Development and Optimization Join the Community Enhance your tableting skills by joining MySTYL’Xxx.xxx resource center and user community to share information and access a comprehensive library of STYL’One scientific content. SCIENCE LABORATORY INNOVATION CENTER INNOVATION CENTER MEDELPHARM LYON KORSCH BERLIN KORSCH BOSTON Formulation Development Services XXXXXX and MEDELPHARM scientists have been collaborating with customers on tableting projects for decades. Our mission and passion are problem solving and helping accelerate your product development. Our international network of tableting experts and laboratories is equipped with the latest techno- logy to provide formulation services from early API character- ization all the way to high-speed process optimization. All we need from you is a few grams of powder to generate data and suggestions to help with your decision making. STYL’One Nano Machine Specifications Description Punch Stations 1 Punch Type EU/TSM B+D, EU-1-441 and non-standard Die Type BBS, BB, B, D and non-standard Max. Production Output tabs/h 1,800 Max. Tablet Diameter mm 25 or 40 (non-standard) Max. Die Filling Height mm 21 (B), 23 (D), 34 (non-standard) Compression Mode Force or displacement driven Upper Punch Penetration Depth mm 3 fixed Max. Precompression Force kN 50 Max. Main Compression Force kN 50 Load Application Lower punch Lower Punch Velocity m/s 90 Lower Punch Acceleration mm/s2 8,000 Dwell Time millisecond 2 – 3,000 Tablet Format Single-layer only Power Supply Voltage 220 VAC 3-Phase (60 Hz) Peak Power W 3,600 Electric Protection A 16 Fault Current Protection mA 30 Compressed Air Bars 10 L / min (nominal) 6 Weight kg 255 Load distribution kg/m² 910 Technical modifications reserved. The technical specifications included in this document represent optimal parameters and are dependent on product quality and machine settings. KORSCH Global Service Network ƒ Europe, Near East, Africa Phone: +00 00 00000-000 xxxxxxx@xxxxxx.xx ƒ America Phone: +0-000-XXXXXX-0 xxxxxxx@xxxxxxxxxxxxx.xxx ƒ Eastern Asia and South-East Asia xxx.xxxxxxxx-xxxxxx.xx Phone: +000 00000000 xxxxxxx.xxxx@xxxxxx.xx

Advanced Training. ƒ ▪ The STYL’one Nano is a sophisticated compression data acquisition tool, and to ensure that the full capability of the system can be realized, our teams of experts can provide advanced training to convey best practices for experimental design, data acquisition, data analysis and interpretation of the results. ƒ ▪ Characterize APIs & Excipients ƒ ▪ Formulation Development and Optimization Join the Community Enhance your tableting skills by joining MySTYL’Xxx.xxx resource center and user community to share information and access a comprehensive library of STYL’One scientific content. SCIENCE LABORATORY INNOVATION CENTER INNOVATION CENTER MEDELPHARM LYON KORSCH BERLIN KORSCH BOSTON Formulation Development Services XXXXXX and MEDELPHARM scientists have been collaborating with customers on tableting projects for decades. Our mission and passion are problem solving and helping accelerate your product development. Our international network of tableting experts and laboratories is equipped with the latest techno- logy to provide formulation services from early API character- ization all the way to high-speed process optimization. All we need from you is a few grams of powder to generate data and suggestions to help with your decision making. STYL’One Nano Machine Specifications Description Punch Stations 1 Punch Type EU/TSM B+D, EU-1-441 and non-standard Die Type BBS, BB, B, D and non-standard Max. Production Output tabs/h 1,800 Max. Tablet Diameter mm 25 or 40 (non-standard) Max. Die Filling Height mm 21 (B), 23 (D), 34 (D or non-standard) Compression Mode Force or displacement driven Upper Punch Penetration Depth mm 3 fixed Max. Precompression Force kN 50 Max. Main Compression Force kN 50 Load Application Lower punch Lower Punch Velocity mmm/s 90 Lower Punch Acceleration mm/s2 8,000 Dwell Time millisecond 2 – 3,000 Tablet Format Single-layer only Power Supply Voltage Europe: 230 V 1-Phase 50/60 Hz USA: 220 VAC V 3-Phase (60 Hz) Hz Peak Power W 3,600 Electric Protection A 16 Fault Current Protection mA 30 Compressed Air Bars 10 L / min (nominal) 6 Weight kg 255 Load distribution kg/m² mx 910 Technical modifications reserved. The technical specifications included in this document represent optimal parameters and are dependent on product quality and machine settings. KORSCH Global Service Network ƒ ◾ Europe, Near East, Africa Phone: +00 00 00000-000 xxxxxxx@xxxxxx.xx ƒ ◾ America Phone: +0-000-XXXXXX-0 xxxxxxx@xxxxxxxxxxxxx.xxx ƒ ◾ Eastern Asia and South-East Asia xxx.xxxxxxxx-xxxxxx.xx Phone: +000 +00 00 00000-000 xxxxxxx@xxxxxx.xx xxx.xxxxxxxx-xxxxxx.xx ◾ Southern Asia Phone: +00 00 00000000 xxxxxxx.xxxx@xxxxxx.xxxxxxxxx@xxxxxxxxxxx.xxx ◾ INNOVATION CENTERS 97000660–08/2022 xxx.x-x-xx-xxxxx.xxx

Advanced Training. ƒ The STYL’one Nano STYL’One Evo is a sophisticated compression data acquisition tool, and to ensure that the full capability of the system can be realized, our teams team of experts can provide advanced training to convey best practices for experimental design, data acquisitionacquisi- tion, data analysis analysis, and interpretation of the results. ƒ Characterize ▪ Understanding your APIs & Excipients ƒ ▪ Product characterization ▪ Formulation Development and Optimization ▪ Scale-up ▪ Troubleshooting Join the Community Enhance your tableting skills by joining MySTYL’Xxx.xxx MySTYL’One resource center and user community to share information and access a comprehensive library of STYL’One scientific content. SCIENCE LABORATORY INNOVATION CENTER INNOVATION CENTER MEDELPHARM LYON KORSCH BERLIN KORSCH BOSTON Formulation Development Services XXXXXX and MEDELPHARM scientists have been collaborating with customers on tableting projects for decades. Our mission and passion are problem solving and helping accelerate your product development. Our international network of tableting experts and laboratories is equipped with the latest techno- logy to provide formulation services from early API character- ization all the way to high-speed process optimization. All we need from you is a few grams of powder to generate data and suggestions to help with your decision making. STYL’One Nano Evo Machine Specifications Description Punch Stations 1 Punch Tool Type EU/EU / TSM B+D, EU-1-441 B and D and non-standard Die Type BBS, BB, B, D and non-standard Max. Production Output tabs/h 1,800 1,750 Max. Tablet Diameter mm 25 or 40 (non-standard) Max. Die Filling Height mm 21 (B), 23 (D), 34 (non-standard) Compression Mode Force or displacement driven Upper Punch Penetration Depth mm 3 fixed 2 – 12 Max. Precompression Force kN 50 (80 optional) Max. Main Compression Force kN 50 (80 optional) Load Application Lower Upper and/or lower punch Lower Punch Velocity (each) mm/s 490 Powder Bed Reduction m/s 90 Lower ~ 1.2 Punch Acceleration mm(each) m/s2 8,000 25,000 Dwell Time millisecond 2 – 3,000 Tablet Format Single-layer only Power Supply Voltage 220 VAC Europe: 400 V 3-Phase (60 Hz) Peak 50/60 Hz USA: 480 V 3-Phase 50/60 Hz Power W 3,600 kW 7 kW nominal 2 kW during operation Electric Protection A 16 32 (Type C) Fault Current Protection mA 30 Leakage current : 300 (Type Asi) Compressed Air air (Tab-in-Tab option and/or external lubrication pack) Bars 10 L / L/min (nominal) 6 10 Flow required for aspiration m3/h 10 – 30 Weight kg 255 1,075 Load distribution kg/m² 910 mx 2,500 Technical modifications reserved. The technical specifications included in this document represent optimal parameters and are dependent on product quality and machine settings. KORSCH Global Service Network ƒ ◾ Europe, Near East, Africa Phone: +00 00 00000-000 xxxxxxx@xxxxxx.xx ƒ ◾ America Phone: +0-000-XXXXXX-0 xxxxxxx@xxxxxxxxxxxxx.xxx ƒ ◾ Eastern Asia and South-East Asia xxx.xxxxxxxx-xxxxxx.xx Phone: +000 +00 00 00000-000 xxxxxxx@xxxxxx.xx xxx.xxxxxxxx-xxxxxx.xx ◾ Southern Asia Phone: +00 00 00000000 xxxxxxx.xxxx@xxxxxx.xxxxxxxxx@xxxxxxxxxxx.xxx ◾ INNOVATION CENTERS 97000658–08/2022 xxx.x-x-xx-xxxxx.xxx

Advanced Training. ƒ The STYL’one Nano STYL’One Evo is a sophisticated compression data acquisition tool, and to ensure that the full capability of the system can be realized, our teams team of experts can provide advanced training to convey best practices for experimental design, data acquisitionacquisi- tion, data analysis analysis, and interpretation of the results. ƒ Characterize ▪ Understanding your APIs & Excipients ƒ ▪ Product characterization ▪ Formulation Development and Optimization ▪ Scale-up ▪ Troubleshooting Join the Community Enhance your tableting skills by joining MySTYL’Xxx.xxx MySTYL’One resource center and user community to share information and access a comprehensive library of STYL’One scientific content. SCIENCE LABORATORY INNOVATION CENTER INNOVATION CENTER MEDELPHARM LYON KORSCH BERLIN KORSCH BOSTON Formulation Development Services XXXXXX and MEDELPHARM scientists have been collaborating with customers on tableting projects for decades. Our mission and passion are problem solving and helping accelerate your product development. Our international network of tableting experts and laboratories is equipped with the latest techno- logy to provide formulation services from early API character- ization all the way to high-speed process optimization. All we need from you is a few grams of powder to generate data and suggestions to help with your decision making. STYL’One Nano Evo Machine Specifications Description Punch Stations 1 Punch Tool Type EU/EU / TSM B+D, EU-1-441 B and D and non-standard Die Type BBS, BB, B, D and non-standard Max. Production Output tabs/h 1,800 1,750 Max. Tablet Diameter mm 25 or 40 (non-standard) Max. Die Filling Height mm 21 (B), 23 (D), 34 (non-standard) Compression Mode Force or displacement driven Upper Punch Penetration Depth mm 3 fixed 2 – 12 Max. Precompression Force kN 50 (80 optional) Max. Main Compression Force kN 50 (80 optional) Load Application Lower Upper and/or lower punch Lower Punch Velocity (each) m/s 90 Lower 590 Powder Bed Reduction m/s ~ 1.2 Punch Acceleration mm(each) m/s2 8,000 25,000 Dwell Time millisecond 2 – 3,000 Tablet Format Single-layer only Power Supply Voltage 220 480 VAC 3-Phase (60 Hz) Peak no neutral Power W 3,600 kW 7 kW nominal 2 kW during operation Electric Protection A 16 32 (Type C) Fault Current Protection mA 30 Leakage current : 300 (Type Asi) Compressed Air air (Tab-in-Tab option and/or external lubrication pack) Bars 10 L / L/min (nominal) 6 10 Flow required for aspiration m3/h 10 – 30 Weight kg 255 1,075 Load distribution kg/m² 910 mx 2,500 Technical modifications reserved. The technical specifications included in this document represent optimal parameters and are dependent on product quality and machine settings. KORSCH Global Service Network ƒ ◾ Europe, Near East, Africa Phone: +00 00 00000-000 xxxxxxx@xxxxxx.xx ƒ ◾ America Phone: +0-000-XXXXXX-0 xxxxxxx@xxxxxxxxxxxxx.xxx ƒ ◾ Eastern Asia and South-East Asia xxx.xxxxxxxx-xxxxxx.xx Phone: +000 00000000 xxxxxxx.xxxx@xxxxxx.xxxxxxxxx.xxxx@xxxxxx.xx xxx.xxxxxxxx-xxxxxx.xx ◾ Southern Asia Phone: +00 00 00000000 xxxxxxx@xxxxxxxxxxx.xxx ◾ INNOVATION CENTERS 97000658–01/2021 xxx.x-x-xx-xxxxx.xxx

Advanced Training. ƒ The STYL’one Nano STYL’One Evo is a sophisticated compression data acquisition tool, and to ensure that the full capability of the system can be realized, our teams team of experts can provide advanced training to convey best practices for experimental design, data acquisitionacquisi- tion, data analysis analysis, and interpretation of the results. ƒ Characterize Understanding your APIs & Excipients ƒ Product characterization ƒ Formulation Development and Optimization ƒ Scale-up ƒ Troubleshooting Join the Community Enhance your tableting skills by joining MySTYL’Xxx.xxx MySTYL’One resource center and user community to share information and access a comprehensive library of STYL’One scientific content. SCIENCE LABORATORY INNOVATION CENTER INNOVATION CENTER MEDELPHARM LYON KORSCH BERLIN KORSCH BOSTON Formulation Development Services XXXXXX and MEDELPHARM scientists have been collaborating with customers on tableting projects for decades. Our mission and passion are problem solving and helping accelerate your product development. Our international network of tableting experts and laboratories is equipped with the latest techno- logy to provide formulation services from early API character- ization all the way to high-speed process optimization. All we need from you is a few grams of powder to generate data and suggestions to help with your decision making. STYL’One Nano Evo Machine Specifications Description Punch Stations 1 Punch Tool Type EU/EU / TSM B+D, EU-1-441 B and D and non-standard Die Type BBS, BB, B, D and non-standard Max. Production Output tabs/h 1,800 1,750 Max. Tablet Diameter mm 25 or 40 (non-standard) Max. Die Filling Height mm 21 (B), 23 (D), 34 (non-standard) Compression Mode Force or displacement driven Upper Punch Penetration Depth mm 3 fixed 2 – 12 Max. Precompression Force kN 50 (80 optional) Max. Main Compression Force kN 50 (80 optional) Load Application Lower Upper and/or lower punch Lower Punch Velocity (each) m/s 90 Lower 590 Powder Bed Reduction m/s ~ 1.2 Punch Acceleration mm(each) m/s2 8,000 25,000 Dwell Time millisecond 2 – 3,000 Tablet Format Single-layer only Power Supply Voltage 220 480 VAC 3-Phase (60 Hz) Peak no neutral Power W 3,600 kW 7 kW nominal 2 kW during operation Electric Protection A 16 32 (Type C) Fault Current Protection mA 30 Leakage current : 300 (Type Asi) Compressed Air air (Tab-in-Tab option and/or external lubrication pack) Bars 10 L / L/min (nominal) 6 10 Flow required for aspiration m3/h 10 – 30 Weight kg 255 1,075 Load distribution kg/m² 910 2,500 Technical modifications reserved. The technical specifications included in this document represent optimal parameters and are dependent on product quality and machine settings. KORSCH Global Service Network ƒ Europe, Near East, Africa Phone: +00 00 00000-000 xxxxxxx@xxxxxx.xx ƒ America Phone: +0-000-XXXXXX-0 xxxxxxx@xxxxxxxxxxxxx.xxx ƒ Eastern Asia and South-East Asia xxx.xxxxxxxx-xxxxxx.xx Phone: +000 00000000 xxxxxxx.xxxx@xxxxxx.xx