Rheumatoid Arthritis model Sample Clauses

Rheumatoid Arthritis model. Adjuvant arthritis was induced in Xxxxx rats (six-week-old male Xxxxx rats obtained from Xxxxxx, Xxxxxx) by injection of incomplete Xxxxxx’x adjuvant. Xxxxxx’x incomplete adjuvant was prepared by suspending heat-killed Mycobacterium Tuberculosis (Difco, Detroit, MI) in mineral oil at 10 mg/ml. Rats were injected intradermally with 100 µl adjuvant at the base of the tail. Arthritis developed by day 10 post injection. Evaluation of the effect of anti – eotaxin-2 antibodies, compared with nonspecific IgG and PBS as controls, on adjuvant induced arthritis: Rats (8 per group) were treated by intraperitoneal (IP) injection with 3 monoclonal antibodies against Xxxxxxx-0, (X0, X0, D8) 3X/week. Controls were treated with total mouse (non specific) IgG or PBS. Injections were started on the third day after adjuvant administration and were performed three times a week until the rats were sacrificed.
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Related to Rheumatoid Arthritis model

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