Preclinical Candidate definition

Preclinical Candidate means a Collaboration Compound for which a [**] has been made.
Preclinical Candidate shall have the meaning given it in the Collaboration Agreement.
Preclinical Candidate means a compound which is or is derived from a Lead Compound which is determined by the Research Committee to be appropriate for pharmacology, toxicology, ADME, formulation and process development studies for IND filing in the Sumitomo Territory.

Examples of Preclinical Candidate in a sentence

  • In addition, each such report by Merck shall include the approval or designation of any Preclinical Candidate during such period.

  • The parties shall designate a Preclinical Candidate before commencing Preclinical.

  • For clarity, the Parties may agree in writing to conduct additional activities as part of the Research Program beyond those specified in the initial Research Plans (e.g., development of Collaboration Compounds meeting Preclinical Candidate criteria), but any such activities shall require additional funding and mutual written agreement on modifications to the relevant Research Plan and Budget.

  • After approval of an IND for a Preclinical Candidate, the Research Committee may designate that Preclinical Candidate as a Clinical Candidate for the purposes of this Section 3.5. Neither party will commence Clinical Development of any Collaboration Compound or Derivative before such compound has been designated as a Clinical Candidate in accordance with this Section.

  • Upon completion of the Research Plan activities for the Additional Molecules, the Joint Research Committee shall make a recommendation as to whether an Additional Molecule should be further advanced as a Preclinical Candidate (“PCC”) and presented for PCC nomination to Merck’s internal governance committee.

  • Without limiting the generality of the foregoing, during the Term, Merck and its Related Parties shall not initiate or conduct, or have conducted, IND-Enabling GLP Toxicology Studies or any Clinical Trial of, or sell, offer for sale or have sold any Collaboration Compound or any Product, unless Merck has approved such Collaboration Compound as a Preclinical Candidate.

  • Promptly (but no later than thirty (30) days) following approval of the first Preclinical Candidate, Merck and Metabasis shall establish a Joint Development Committee (the “Joint Development Committee” or “JDC”) with an equal number of (not to exceed four (4)) representatives of each party.


More Definitions of Preclinical Candidate

Preclinical Candidate means a Collaboration Compound that the Research Committee has selected for Preclinical Development.
Preclinical Candidate means a Collaboration Compound that Merck’s Preclinical Development Review Committee (or its successor committee) approves for entry into IND-Enabling GLP Toxicology Studies or that is actually entered into IND-Enabling GLP Toxicology Studies by Merck or a Related Party.

Related to Preclinical Candidate

  • Development Candidate means a Compound that meets the Development Candidate Criteria for the initiation of a Development Program for the treatment of CF, and which is the subject of a notice from Vertex to CFFT that Vertex intends to commence formal pre-clinical development of the Compound in the Field pursuant to the provisions of Section 3.1 hereof.

  • Product Candidate means, [***].

  • Collaboration Target means the Initial Collaboration Targets set forth on Exhibit F and any Additional Target or Substitute Target that is selected in accordance with Section 3.3 of this Agreement.

  • Collaboration Compound means any of the following: (a) FG-4592, (b) any HIF Compound (other than FG-4592) that is added to this Agreement pursuant to Section 3.6, and (c) any salts, esters, complexes, chelates, crystalline and amorphous morphic forms, pegylated forms, enantiomers (excluding regioisomers), prodrugs, solvates, metabolites and catabolites of any of the foregoing ((a) or (b)).

  • Clinical Studies means human clinical trials for a Licensed Product and any other tests and studies for a Licensed Product in human subjects.