FG-4592 definition

FG-4592 means the molecule with the chemical structure set forth on Exhibit C.
Sample 1Sample 2Sample 3
FG-4592 means the molecule with the chemical structure set forth on Exhibit A.
Sample 1Sample 2Sample 3

Examples of FG-4592 in a sentence

  • An asterisk above a bar indicates the FG-4592 or PX- 478 treatment differed from that of the nontreated control (t test, P < 0.01).

  • To FibroGen’s knowledge, the research, development, manufacture, use and sale after the Effective Date of FG-4592 in the CKD Indications can be carried out in the manner reasonably contemplated as of the Effective Date without infringing any published patent applications or patents owned or controlled by a Third Party.

  • FibroGen WFOE is pursuing a Class 1.1 Innovative Drug pathway in China to develop, manufacture and commercialize such compounds in China, including FG-4592, to which FibroGen WFOE has certain intellectual property rights.

  • HIF Stabilizers, including Roxadustat (FG-4592), Molidustat (BAY 85-3934), FG- 2216, and BAY 87-2243.

  • The Council wanted to give the consultation the widest possible publicity, and on the first day issued a press release tolaunch it.

  • Hypoxia-inducible factor (HIF) stabilizers, e.g. cobalt, molidustat and roxadustat (FG-4592); and HIF activators,e.g. argon and xenon.

  • As one of the few longitudinal studies in Australia - and importantly a study collecting data on a representative sample - it is a valuable resource for the sort of descriptive epidemiology (incidence, prevalence, severity distribution) that underlies burden of disease estimations.

  • Randomized placebo-controlled dose-ranging and pharmacodynamics study of roxadustat (FG-4592) to treat anemia in nondialysis-dependent chronic kidney disease (NDD-CKD) patients.

  • Effect of FG-4592 in a Rat Model of Anemia of Chronic Disease.301_05_3510_047 (ACD6).

  • The drug may some- day be developed for other anemia conditions, AstraZen- eca said on its website.Right now, AstraZeneca will pay $350 million up front, plus development-related milestone payments of up to $465 million, for a total of $815 million for rights to FG-4592 in the United States, China, and selected markets.

Related to FG-4592

  • NI 51-102 means National Instrument 51-102 – Continuous Disclosure Obligations;

  • NI 81-102 means National Instrument 81-102 – Investment Funds.

  • ug/l means micrograms per liter.

  • O. Reg. 419/05 means the Ontario Regulation 419/05, Air Pollution – Local Air Quality.

  • NI 44-102 means National Instrument 44-102 – Shelf Distributions;

  • MI 11-102 means Multilateral Instrument 11-102 – Passport System;

  • NI 51-101 means National Instrument 51-101 Standards of Disclosure for Oil and Gas Activities;

  • NZOC means the New Zealand Olympic Committee Incorporated.

  • NI 45-102 means National Instrument 45-102 – Resale of Securities.

  • H1, H2 etc means First Highest, Second Highest Offers etc. in Disposal Tenders means

  • NI 31-103 means National Instrument 31-103 Registration Requirements, Exemptions and Ongoing Registrant Obligations;

  • NI 58-101 means National Instrument 58-101 Disclosure of Corporate Governance Practices;

  • Phase 4 Clinical Trial means a Clinical Trial of a Product conducted after Regulatory Approval of such Product has been obtained from an appropriate Regulatory Authority, which trial is (a) conducted voluntarily by a Party to enhance marketing or scientific knowledge of the Product, or (b) conducted due to a request or requirement of a Regulatory Authority.

  • NI 41-101 means National Instrument 41-101 – General Prospectus Requirements;

  • B.E.P.D. means an entity certified as a Business enterprise owned or operated by people with disabilities as defined in MCC Section 2-92-586.

  • €STRi-pTBD means, in respect of any TARGET Business Day falling in the relevant Interest Accrual Period, the €STR for the TARGET Business Day falling “p” TARGET Business Days prior to the relevant TARGET Business Day “i”;

  • NI 44-101 means National Instrument 44-101 – Short Form Prospectus Distributions;

  • Pivotal Clinical Trial means, with respect to a Licensed Product, (a) a phase 3 Clinical Trial or (b) any other clinical trial that is intended (as of the time the study is initiated) to obtain the results and data to support (without the need to conduct any additional clinical trial) the filing of an application for Regulatory Approval for such product.

  • MI 61-101 means Multilateral Instrument 61-101 – Protection of Minority Security Holders in Special Transactions;

  • Phase 3 Clinical Trial means a pivotal clinical trial in humans performed to gain evidence with statistical significance of the efficacy of a product in a target population, and to obtain expanded evidence of safety for such product that is needed to evaluate the overall benefit-risk relationship of such product, to form the basis for approval of an NDA and to provide an adequate basis for physician labeling, as described in 21 C.F.R. § 312.21(c) or the corresponding regulation in jurisdictions other than the United States.

  • NI 43-101 means National Instrument 43-101 – Standards of Disclosure for Mineral Projects;

  • Polystyrene foam means blown polystyrene and expanded and

  • PTCE 95-60 As defined in Section 5.02(b). PUD: A planned unit development.

  • Silicone-based Multi-purpose Lubricant means any lubricant which is:

  • Phase III Clinical Trial means a human clinical trial, the principal purpose of which is to demonstrate clinically and statistically the efficacy and safety of a Licensed Product for one or more indications in order to obtain Marketing Approval of such Licensed Product for such indication(s), as further defined in 21 C.F.R. §312.21 or a similar clinical study in a country other than the United States.

  • L1. L2 etc means First or second Lowest Offer etc."L1. L2 etc" means First or second Lowest Offer etc. "LC" means Letter of Credit"LC" means Letter of Credit