0001104659-23-003415 Sample Contracts

STRUCTURE THERAPEUTICS INC. INDEMNIFICATION AGREEMENT
Indemnification Agreement • January 12th, 2023 • Structure Therapeutics Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (this “Agreement”) is made as of ________, by and between Structure Therapeutics Inc., an exempted company incorporated and existing under the laws of the Cayman Islands (the “Company”), and [Name of Director/Officer] ([US passport/ID]:[*])

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April 23, 2021 Melita Sun Jung Email: [***] Re: Amended and Restated Offer of Employment Dear Melita:
Structure Therapeutics Inc. • January 12th, 2023 • Pharmaceutical preparations • California

As you know, ShouTi Inc., a Delaware corporation (the “Company”), entered into an employment offer letter with you on February 14, 2021 (the “Offer Letter”). You and the Company hereby agree to amend and restate the Offer Letter. The terms and conditions set forth in this letter agreement (the “Agreement”) shall become effective as of the date hereof, and shall supersede and replace the terms and conditions set forth in the Offer Letter.

EMPLOYMENT CONTRACT
Employment Contract • January 12th, 2023 • Structure Therapeutics Inc. • Pharmaceutical preparations
SHOUTI INC. EXECUTIVE EMPLOYMENT AGREEMENT for RAYMOND STEVENS
Executive Employment Agreement • January 12th, 2023 • Structure Therapeutics Inc. • Pharmaceutical preparations • California

This Executive Employment Agreement (this “Agreement”), is made and entered into effective as of May 16, 2019 (the “Effective Date”), by and between Raymond Stevens (“Employee”) and ShouTi Inc., a Delaware corporation (the “Company”).

March 2, 2022 Sharon Tetlow Dear Sharon:
Structure Therapeutics Inc. • January 12th, 2023 • Pharmaceutical preparations

We are delighted that you have agreed to join the Board of Directors (the “Board”) of ShouTi Inc. (the “Company”) and to serve as the Chair of the Audit Committee of the Board (the “Audit Chair”). This letter sets forth the agreement between you and the Company regarding your Board membership (the “Agreement”):

AMENDMENT NO. 1 TO EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • January 12th, 2023 • Structure Therapeutics Inc. • Pharmaceutical preparations • California

This AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT (this “First Amendment”) is made and entered into as of December 5, 2022 by and between Structure Therapeutics USA Inc., a Delaware corporation (the “Company”), and Jun Yoon, an individual resident in the State of California (the “Employee”) (the Company and the Employee are hereinafter sometimes individually referred to as a “Party” and together referred to as the “Parties”).

COLLABORATION AGREEMENT
Collaboration Agreement • January 12th, 2023 • Structure Therapeutics Inc. • Pharmaceutical preparations • New York

This Collaboration Agreement (the “Agreement”) is effective as of October 9, 2020 (the “Effective Date”) by and between Schrödinger, LLC, a Delaware limited liability company, having an address of 120 West 45th Street, 17th Floor, New York, New York 10036 (“Schrödinger”), and Lhotse Bio, Inc., a Delaware corporation having an address of 611 Gateway Blvd Suite 223, South San Francisco, CA 94080 (“Lhotse”). Each of Schrödinger and Lhotse may hereinafter be referred to as a “party” to this Agreement or collectively as the “parties”.

November 23, 2022 Joanne Waldstreicher Dear Joanne:
Structure Therapeutics Inc. • January 12th, 2023 • Pharmaceutical preparations

We are delighted that you have agreed to join the Board of Directors (the “Board”) of Structure Therapeutics Inc. (the “Company”). This letter sets forth the agreement between you and the Company regarding your Board membership (the “Agreement”):

SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • January 12th, 2023 • Structure Therapeutics Inc. • Pharmaceutical preparations • California

THIS SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT (this “Agreement”) is made as of July 30, 2021, by and among ShouTi Inc., an exempted company limited by shares incorporated under the laws of the Cayman Islands (the “Company”), and the investors set forth in Schedule A attached hereto (each, an “Investor” and collectively, the “Investors”).

Supplemental Agreement
Supplemental Agreement • January 12th, 2023 • Structure Therapeutics Inc. • Pharmaceutical preparations

Shanghai Basecamp Biotechnology Co., Ltd. (hereinafter referred to as “Shanghai Basecamp”), a corporation formally organized and validly existing under the laws of the PRC with its address of Room 5-129, No5-123, South Building 1, No. 4560 Jinke Road, China (Shanghai) Pilot Free Trade Zone and legal representative of RAYMOND CHARLES STEVENS;

December 10th, 2021 Daniel Welch Dear Dan:
Structure Therapeutics Inc. • January 12th, 2023 • Pharmaceutical preparations

We are delighted that you have agreed to join the Board of Directors (the “Board”) of ShouTi Inc. (the “Company”) and to serve as the Chairman of the Board. This letter sets forth the agreement between you and the Company regarding your Board membership (the “Agreement”):

SHANGHAI PREMISES LEASE CONTRACT
Premises Lease Contract • January 12th, 2023 • Structure Therapeutics Inc. • Pharmaceutical preparations • Shanghai

THIS CONTRACT is made and entered into by and between Party A and Party B, through mutual friendly negotiation based on the principles of equality, voluntariness, fairness and good faith, regarding the lease by Party A to Party B of the real property which Party A is entitled to lease, in accordance with the Contract Law of the People’s Republic of China and the Regulations of Shanghai Municipality for Premises Lease (hereinafter as “Regulations”), with the terms and conditions as follows.

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