WITNESSETH:Employment Agreement • March 29th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • Washington
EXHIBIT 10.10 WARRANT AGREEMENTWarrant Agreement • April 15th, 1999 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • New York
EXHIBIT 10.23 STOCK PURCHASE AGREEMENT DATED FEBRUARY 14, 2000Stock Purchase Agreement • March 30th, 2000 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • Washington
EXHIBIT 4.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this "Agreement") is made and entered into as of February 23, 2004, by and among Epoch Biosciences, Inc., a Delaware corporation (the "Company"), and the investors signatory...Registration Rights Agreement • February 25th, 2004 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances
EXHIBIT 10.32 LOAN AND SECURITY AGREEMENT EPOCH BIOSCIENCES, INC.Loan and Security Agreement • November 14th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • Washington
EXHIBIT 10.31 CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION. June 10, 2002 William G. Gerber, MD...Letter Agreement • August 14th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • California
ARTICLE I. DEFINITIONSSecurities Purchase Agreement • February 25th, 2004 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • New York
AGREEMENTLicense Agreement • August 13th, 2004 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • California
RECITALS:Employment Agreement • November 15th, 2004 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances
EXHIBIT 10.32.1 LOAN MODIFICATION AGREEMENT This Loan Modification Agreement is entered into as of September 18, 2003, by and between Epoch Biosciences, Inc. (the "Borrower") and Silicon Valley Bank ("Bank"). 1. DESCRIPTION OF EXISTING OBLIGATIONS:...Loan Modification Agreement • November 7th, 2003 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances
EXHIBIT 10.22 CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION AMENDED AND RESTATED LICENSE AND...Security Agreement • November 15th, 1999 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • California
EXHIBIT 10.22 STOCK PURCHASE AGREEMENT DATED NOVEMBER 1, 1999Stock Purchase Agreement • March 30th, 2000 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • Washington
1 EXHIBIT 1 WARRANT AGREEMENTWarrant Agreement • February 18th, 1999 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • New York
RECITALSEmployment Agreement • March 31st, 2003 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances
SUBLEASESublease • May 10th, 1999 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances
EXHIBIT 4.3 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION...Securities Purchase Agreement • February 25th, 2004 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances
1 EXHIBIT 10.69 ASSET PURCHASE AGREEMENT THIS ASSET PURCHASE AGREEMENT (this "Agreement") is made as of November 26, 1996, by and between EPOCH PHARMACEUTICALS, INC., a Delaware corporation, ("Seller") and Saigene Corporation, a Delaware corporation...Asset Purchase Agreement • August 14th, 1997 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • Washington
RECITALSStock and Warrant Purchase Agreement • November 14th, 1996 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • Delaware
AMENDMENT NO. 1 TO SECOND AMENDED AND RESTATED COLLABORATION, LICENSE AND SUPPLY AGREEMENT BETWEEN EPOCH BIOSCIENCES, INC. (FORMERLY EPOCH PHARMACEUTICALS, INC.) AND APPLERA CORPORATION (SUCCESSOR TO PERKIN-ELMER CORPORATION)License and Supply Agreement • August 14th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances
BETWEENAsset Purchase Agreement • June 16th, 2003 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • California
EXHIBIT 2.1 EXECUTION COPY ASSET PURCHASE AGREEMENT THIS ASSET PURCHASE AGREEMENT (the "Agreement") is made as of November 15, 2000, by and between EPOCH BIOSCIENCES, INC., a Delaware corporation, ("Buyer") and IMMUNE COMPLEX CORPORATION ("Seller"), a...Asset Purchase Agreement • November 27th, 2000 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • California
WITNESSETH:Employment Agreement • August 14th, 2001 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • Washington
WITNESSETH:Employment Agreement • August 14th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • Washington
WITNESSETH:Employment Agreement • March 29th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • Washington
Dated as of February 25, 1998 BRIDGE FINANCING AGREEMENT THE BAY CITY CAPITAL FUND I, L.P., a Delaware limited partnership c/o Bay City Capital LLC 750 Battery Street, Suite 600 San Francisco, California 94111 Gentlemen: The undersigned, EPOCH...Bridge Financing Agreement • April 15th, 1998 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • Washington
WITNESSETH:Employment Agreement • May 1st, 2000 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • Washington
1 EXHIBIT 10.1 LEASE (Nexus/Epoch Pharmaceuticals, Inc.) THIS LEASE ("Lease") is made as of February __, 2000, by and between Nexus Canyon Park LLC, a California limited liability company ("Landlord"), and Epoch Pharmaceuticals, Inc., a Delaware...Epoch Biosciences Inc • November 14th, 2000 • In vitro & in vivo diagnostic substances • Washington
EXHIBIT 10.21.1 CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24B-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION SECOND AMENDED AND RESTATED...License and Supply Agreement • March 29th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • California
EXECUTION COPY EXCLUSIVE DISTRIBUTION AND LICENSE AGREEMENT THIS EXCLUSIVE DISTRIBUTION AND LICENSE AGREEMENT is made and entered into as of the 25th day of July 2002 (this "Agreement"), between EPOCH BIOSCIENCES, INC., a Delaware corporation...Exclusive Distribution and License Agreement • November 14th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • Washington
EXHIBIT 10.40 CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION. April 5, 2004 Qiagen NV c/o Qiagen...Epoch Biosciences Inc • August 13th, 2004 • In vitro & in vivo diagnostic substances • West Coast
EXHIBIT 10.26.1 November 13, 2001 Bay City Capital LLC 750 Battery Street, Suite 600 San Francisco, CA 94111 Attn: Sanford S. Zweifach Re: Extension of Letter Agreement between Epoch Biosciences, Inc. and Bay City Capital BD LLC Dear Mr. Zweifach:...Epoch Biosciences Inc • March 29th, 2002 • In vitro & in vivo diagnostic substances
Reference is made to the Letter Agreement between Epoch Biosciences, Inc. (the "Company") and Bay City Capital BD, LLC., (the "Advisor") dated November 7, 2000 with respect to the engagement of Advisor by the Company (the "Agreement").
EXHIBIT 10.21.1 CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24B-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION FIRST AMENDMENT TO THE LICENSE AND...Epoch Pharmaceuticals Inc • August 9th, 1999 • In vitro & in vivo diagnostic substances
AGREEMENT AND PLAN OF MERGER AND REORGANIZATION among NANOGEN, INC. EMPIRE ACQUISITION CORP. and EPOCH BIOSCIENCES, INC. Dated as of September 7, 2004Agreement and Plan of Merger and Reorganization • September 8th, 2004 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • Delaware
AGREEMENT AND PLAN OF MERGER AND REORGANIZATION, dated as of September 7, 2004 (as amended, supplemented or otherwise modified from time to time, this “Agreement”), among NANOGEN, INC., a Delaware corporation (“Parent”), EPOCH BIOSCIENCES, INC., a Delaware corporation (“Company”), and EMPIRE ACQUISITION CORP., a Delaware corporation and a direct wholly owned Subsidiary of Parent (“Merger Sub”):
EXECUTION COPY CO-EXCLUSIVE LICENSE AND SUPPLY AGREEMENT THIS CO-EXCLUSIVE LICENSE AND SUPPLY AGREEMENT (this "Agreement") is made and entered into as of the 4th day of November 2002 (the "Effective Date"), between EPOCH BIOSCIENCES, INC., a Delaware...License and Supply Agreement • March 31st, 2003 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • Delaware
BACKGROUNDFirst Side Agreement • March 29th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances
