Dyne Therapeutics, Inc. Sample Contracts

INDEMNIFICATION AGREEMENT
Indemnification Agreement • August 25th, 2020 • Dyne Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (“Agreement”) is made as of , 20 by and between Dyne Therapeutics, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”). This Agreement supersedes and replaces any and all previous Agreements between the Company and Indemnitee covering the subject matter of this Agreement. [[Solely with respect to officers and directors that execute this form of indemnification agreement on or prior to the Company’s initial public offering:] and shall be effective as of the effectiveness of a Registration Statement on Form S-1 relating to the initial registration under the Securities Act of 1933, as amended, of shares of the Company’s common stock].

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UNDERWRITING AGREEMENT DYNE THERAPEUTICS, INC. 17,150,000 Shares of Common Stock, par value $0.0001 per share Underwriting Agreement
Underwriting Agreement • January 5th, 2024 • Dyne Therapeutics, Inc. • Pharmaceutical preparations • New York

Dyne Therapeutics, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters listed in Schedule 1 hereto (the “Underwriters”), for whom you are acting as representatives (the “Representatives”), an aggregate of 17,150,000 shares of common stock, par value $0.0001 per share (the “Common Stock”), of the Company (the “Underwritten Shares”) and, at the option of the Underwriters, up to an additional 2,572,500 shares of Common Stock of the Company (the “Option Shares”). The Underwritten Shares and the Option Shares are herein referred to as the “Shares”. The shares of Common Stock of the Company to be outstanding after giving effect to the sale of the Shares are referred to herein as the “Stock”.

OPEN MARKET SALE AGREEMENTSM
Dyne Therapeutics, Inc. • November 4th, 2021 • Pharmaceutical preparations • New York
DYNE THERAPEUTICS, INC. LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • July 23rd, 2020 • Dyne Therapeutics, Inc. • North Carolina

This LOAN AND SECURITY AGREEMENT (the “Agreement”) is entered into as of February 20, 2020, by and between PACIFIC WESTERN BANK, a California state chartered bank (“Bank”) and DYNE THERAPEUTICS, INC. (collectively with each of the other Persons, if any, that join as a co-Borrower hereunder are collectively referred to as the “Borrowers” and individually as a “Borrower”).

SUMMARY OF BASIC LEASE INFORMATION
Lease • January 19th, 2021 • Dyne Therapeutics, Inc. • Pharmaceutical preparations

This Lease, which includes the preceding Summary and the exhibits attached hereto and incorporated herein by this reference (the Lease, the Summary and the exhibits to be known sometimes collectively hereafter as the “Lease”), dated as of the date set forth in Section 1 of the Summary, is made by and between BP3-BOS1 1560 TRAPELO ROAD LLC, a Delaware limited liability company (“Landlord”), and DYNE THERAPEUTICS, INC., a Delaware corporation (“Tenant”).

DYNE THERAPEUTICS, INC. AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • August 25th, 2020 • Dyne Therapeutics, Inc. • Pharmaceutical preparations • Delaware

THIS AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT (this “Agreement”), is made as of the 7th day of August, 2020, by and among Dyne Therapeutics, Inc., a Delaware corporation (the “Company”), and each of the investors listed on Schedule A hereto, each of which is referred to in this Agreement as an “Investor”.

Dyne Therapeutics, Inc. RESTRICTED STOCK UNIT AGREEMENT
Restricted Stock Unit Agreement • August 25th, 2020 • Dyne Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This grant of RSUs satisfies in full all commitments that the Company has to the Participant with respect to the issuance of stock, stock options or other equity securities.

DYNE THERAPEUTICS, INC. STOCK OPTION AGREEMENT GRANTED UNDER 2018 STOCK INCENTIVE PLAN
Stock Option Agreement • August 25th, 2020 • Dyne Therapeutics, Inc. • Pharmaceutical preparations

This Stock Option Agreement (this “Agreement”) is made between Dyne Therapeutics, Inc., a Delaware corporation (the “Company”), and the Participant pursuant to the 2018 Stock Incentive Plan (the “Plan”).

Dyne Therapeutics, Inc. RESTRICTED STOCK AGREEMENT
Restricted Stock Agreement • August 25th, 2020 • Dyne Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This restricted stock award satisfies in full all commitments that the Company has to the Participant with respect to the issuance of stock, stock options or other equity securities.

VIA ELECTRONIC MAIL
Consulting Agreement • August 5th, 2021 • Dyne Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts

As we have discussed, you are resigning from employment with Dyne Therapeutics, Inc. (the “Company”), effective June 2, 2021 (the “Resignation Date”). As we also discussed, although you are electing to leave the Company, the Company has agreed to provide you with the severance benefits described in paragraph 1 below if you sign and return this letter agreement to me by June 23, 2021 (but no earlier than the Resignation Date) and do not revoke your agreement (as described below). By signing and returning this letter agreement and not revoking your acceptance, you will be entering into a binding agreement with the Company and will be agreeing to the terms and conditions set forth in the numbered paragraphs below, including the release of claims set forth in paragraph 2. Therefore, you are advised to consult with an attorney before signing this letter agreement and you have been given at least twenty-one (21) days to do so. If you sign this letter agreement, you may change your mind and r

DYNE THERAPEUTICS, INC. RESTRICTED STOCK AGREEMENT GRANTED UNDER 2018 STOCK INCENTIVE PLAN
Restricted Stock Agreement • July 23rd, 2020 • Dyne Therapeutics, Inc. • Delaware

This Restricted Stock Agreement (the “Agreement”) is made this [ ] day of [ ], 2018, between Dyne Therapeutics, Inc., a Delaware corporation (the “Company”), and [ ] (the “Recipient”).

1560 TRAPELO ROAD LEASE BP3-BOS1 1560 TRAPELO ROAD LLC, a Delaware limited liability company, as Landlord, and DYNE THERAPEUTICS, INC., a Delaware corporation, as Tenant SUMMARY OF BASIC LEASE INFORMATION
Lease • August 5th, 2021 • Dyne Therapeutics, Inc. • Pharmaceutical preparations

This Lease, which includes the preceding Summary and the exhibits attached hereto and incorporated herein by this reference (the Lease, the Summary and the exhibits to be known sometimes collectively hereafter as the “Lease”), dated as of the date set forth in Section 1 of the Summary, is made by and between BP3-BOS1 1560 TRAPELO ROAD LLC, a Delaware limited liability company (“Landlord”), and DYNE THERAPEUTICS, INC., a Delaware corporation (“Tenant”).

VIA ELECTRONIC MAIL March 25, 2024 Joshua Brumm Dear Josh:
Consulting Agreement • March 25th, 2024 • Dyne Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts

As we discussed, your employment with Dyne Therapeutics, Inc. (the “Company”) will end effective March 25, 2024 (the “Separation Date”). As we also discussed, you will be eligible to receive the severance benefits described in paragraph 1 below if you sign and return this letter agreement to me by April 12, 2024 (the “Return Date”), but no earlier than the Separation Date, and do not revoke your acceptance (as described below). By signing and returning this letter agreement and not revoking your acceptance, you will be entering into a binding agreement with the Company and will be agreeing to the terms and conditions set forth in the numbered paragraphs below, including the release of claims set forth in paragraph 2. Therefore, you are advised to consult with an attorney before signing this letter agreement and you have been given at least twenty-one (21) days to do so. If you sign this letter agreement, you may change your mind and revoke your acceptance during the seven (7) business

SUBLEASE AGREEMENT
Sublease Agreement • July 23rd, 2020 • Dyne Therapeutics, Inc. • Massachusetts

This Sublease Agreement (the “Sublease”) is made as of May 20, 2019 (the “Effective Date”) by and between ARRAKIS THERAPEUTICS, INC., a Delaware corporation (“Sublandlord”) and DYNE THERAPEUTICS, INC., a Delaware corporation (“Subtenant”), in the following factual context:

November 29, 2018
Dyne Therapeutics, Inc. • July 23rd, 2020

The Offer Letter dated March 21, 2018 (the “Offer Letter”) between you and Dyne Therapeutics, Inc. (the “Company”) provides that you will serve as the Chief Scientific Officer of the Company and that you will report to the Chief Executive Officer of the Company. In connection with your election to President and Chief Executive Officer of the Company on the date hereof, the Company and you agree as follows:

Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. LICENSE AGREEMENT By and...
License Agreement • July 23rd, 2020 • Dyne Therapeutics, Inc. • New York

This agreement (this “Agreement”), dated the 27 day of April, 2020 (the “Effective Date”), is by and between Dyne Therapeutics Inc., a Delaware corporation with a place of business at 830 Winter Street, Waltham, MA 02451, USA (“Dyne”), and The University of Mons, a university with a place of business at Place du Parc 20, 7000 Mons, Belgium (“UMONS”).

CONSULTING AGREEMENT
Consulting Agreement • March 25th, 2024 • Dyne Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts

This Consulting Agreement (the “Agreement”), effective as of the Effective Date (as defined herein), is entered into between Dyne Therapeutics, Inc. (the “Company”) and Joshua Brumm (the “Consultant”).

Dyne Therapeutics, Inc. STOCK OPTION AGREEMENT
Stock Option Agreement • August 25th, 2020 • Dyne Therapeutics, Inc. • Pharmaceutical preparations

This option satisfies in full all commitments that the Company has to the Participant with respect to the issuance of stock, stock options or other equity securities.

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