Arcturus Therapeutics Holdings Inc. Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • September 27th, 2019 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of September 25, 2019, between Arcturus Therapeutics Holdings Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

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ARCTURUS THERAPEUTICS HOLDINGS INC. Shares of Common Stock (par value $0.001 per share) Controlled Equity OfferingSM Sales Agreement
Sales Agreement • December 23rd, 2022 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

Arcturus Therapeutics Holdings Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cantor Fitzgerald & Co. and Wells Fargo Securities, LLC (each an “Agent” and together, the “Agents”), as follows:

ARCTURUS THERAPEUTICS HOLDINGS INC. INDEMNIFICATION AGREEMENT
Indemnification Agreement • March 16th, 2020 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (“Agreement”) is made as of [__], by and between ARCTURUS THERAPEUTICS HOLDINGS INC., a Delaware corporation (the “Company”), and [__] (“Indemnitee”). This Agreement supersedes and replaces any and all previous Agreements between the Company and Indemnitee covering the subject matter of this Agreement.

UNDERWRITING AGREEMENT
Underwriting Agreement • April 17th, 2020 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

Arcturus Therapeutics Holdings Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell to the several underwriters named in Schedule I hereto (the “Underwriters”) an aggregate of 4,117,650 shares of its common stock, par value $0.001 per share (the “Common Stock”). The 4,117,650 shares of Common Stock to be sold by the Company are called the “Firm Shares.” The Company also proposes to issue and sell to the several Underwriters up to an additional 617,647 shares (the “Additional Shares”) of Common Stock at the option of the Underwriters as provided in Section 2(c) below. The Firm Shares and any Additional Shares purchased by the Underwriters are referred to herein as the “Shares.” Guggenheim Securities, LLC (“Guggenheim”) is acting as representative (the “Representative”) of the several Underwriters in connection with the offering and sale of the Shares contemplated

Contract
Arcturus Therapeutics Holdings Inc. • August 7th, 2023 • Pharmaceutical preparations • New York

CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [***], HAS BEEN OMITTED BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL

ARCTURUS THERAPEUTICS HOLDINGS INC. 2019 OMNIBUS EQUITY INCENTIVE PLAN (Effective June 10, 2019)
Arcturus Therapeutics Holdings Inc. • June 14th, 2019 • Pharmaceutical preparations • Delaware
STRICTLY CONFIDENTIAL Arcturus Therapeutics Holdings Inc. 10628 Science Center Drive, Suite 250 San Diego, California 92121 Attn: Joseph E. Payne, Chief Executive Officer Dear Mr. Payne:
Letter Agreement • September 27th, 2019 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

This letter agreement (this “Agreement”) constitutes the agreement between Arcturus Therapeutics Holdings Inc. (the “Company”) and H.C. Wainwright & Co., LLC (“Wainwright”), that Wainwright shall serve as the sole placement agent or sole book-running manager in an offering of an aggregate of two million shares of the Company’s common stock (the “Securities”) at a price not less than $11.50 per share (the “Offering”) during the Term (as hereinafter defined) of this Agreement. The terms of the Offering and the Securities issued in connection therewith shall be mutually agreed upon by the Company and Wainwright and nothing herein implies that Wainwright would have the power or authority to bind the Company and nothing herein implies that the Company shall have an obligation to issue any Securities. It is understood that Wainwright’s assistance in the Offering will be subject to the satisfactory completion of such investigation and inquiry into the affairs of the Company as Wainwright deem

ARCTURUS THERAPEUTICS HOLDINGS INC. EXECUTIVE EMPLOYMENT AGREEMENT for JOSEPH E. PAYNE
Employment Agreement • June 14th, 2019 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • California

This Executive Employment Agreement (this “Agreement”), is made and entered into by and between Joseph E. Payne (“Executive”) and Arcturus Therapeutics Holdings Inc., a Delaware corporation (the “Company”). This Agreement amends and restates any prior employment agreement previously entered into by Executive and the Company. In consideration of the mutual agreements set forth herein, the Company and Executive hereby agree as follows:

1,365,000 Shares of Common Stock Arcturus Therapeutics Holdings Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • December 8th, 2020 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

Arcturus Therapeutics Holdings Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell to the several underwriters named in Schedule I hereto (the “Underwriters”) an aggregate of 1,365,000 shares of its common stock, par value $0.001 per share (the “Common Stock”). The 1,365,000 shares of Common Stock to be sold by the Company are called the “Firm Shares.” The Company also proposes to issue and sell to the several Underwriters up to an additional 204,750 shares (the “Additional Shares”) of Common Stock at the option of the Underwriters as provided in Section 2(c) below. The Firm Shares and any Additional Shares purchased by the Underwriters are referred to herein as the “Shares.” Piper Sandler & Co. (“Piper Sandler”), Guggenheim Securities, LLC (“Guggenheim”) and Wells Fargo Securities, LLC (“Wells Fargo”) are each acting as representative (the “Representatives”) o

SECURITY AGREEMENT (SECURITIES ACCOUNT)
Security Agreement • August 7th, 2023 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • Delaware

This SECURITY AGREEMENT (SECURITIES ACCOUNT), dated as of April 21, 2023 (as amended, supplemented or otherwise modified from time to time in accordance with the provisions hereof, this “Agreement”), is made by and among ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Grantor”), in favor of WELLS FARGO BANK, NATIONAL ASSOCIATION (“Secured Party”).

CREDIT AGREEMENT
Credit Agreement • August 7th, 2023 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

THIS CREDIT AGREEMENT dated April 21, 2023, is by and between ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Borrower”), and WELLS FARGO BANK, NATIONAL ASSOCIATION (“Bank”).

REDACTED
Development and Option Agreement • August 14th, 2019 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

THIS THIRD AMENDMENT (this “Third Amendment”) to the Development and Option Agreement dated January 1, 2018 (the “Original Agreement”), is entered into by and between CureVac AG, a German stock corporation with offices at Paul-Ehrlich-Strasse 15, 72076 Tubingen, Germany (“CureVac”), and Arcturus Therapeutics Inc., a Delaware corporation with offices at 10628 Science Center Drive #200, San Diego, CA 92121, USA (“Arcturus”; each of CureVac and Arcturus individually a “Party” and together the “Parties”) as of July 26, 2019 (the “Third Amendment Date”).

SUPPLY AGREEMENT
Supply Agreement • November 9th, 2020 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This SUPPLY AGREEMENT (the “Agreement”), dated as of August 17, 2020 (the “Effective Date”), is being entered into by and between Arcturus Therapeutics, Inc., a Delaware corporation (“Arcturus”), and the Israeli Ministry of Health (the “MOH”). Arcturus and the MOH may be referred to herein by name or individually, as a “Party” and collectively, as the “Parties.”

MANUFACTURING SUPPORT AGREEMENT
Manufacturing Support Agreement • November 9th, 2020 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations
REDACTED Certain identified information, indicated by [***], has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm if publicly disclosed. AMENDMENT NO. 4 TO LETTER AGREEMENT
Letter Agreement • November 14th, 2023 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This Amendment No. 4 (“Amendment No. 4”) to the Development Program Letter Agreement of May 16, 2017, as amended on July 13, 2018, July 30, 2019 and December 21, 2021 (as amended, the “Agreement”), is entered into and effective as of September 25, 2023 (the “Amendment No. 4 Effective Date”) by and between Arcturus Therapeutics, Inc. (“Arcturus”) and the Cystic Fibrosis Foundation (“CFF”). Capitalized terms used but not defined herein have the meanings given to them in the Agreement.

3,264,151 Shares of Common Stock Arcturus Therapeutics Holdings Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • July 29th, 2020 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

Arcturus Therapeutics Holdings Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell to the several underwriters named in Schedule I hereto (the “Underwriters”) an aggregate of 3,264,151 shares of its common stock, par value $0.001 per share (the “Common Stock”). The 3,264,151 shares of Common Stock to be sold by the Company are called the “Firm Shares.” The Company also proposes to issue and sell to the several Underwriters up to an additional 489,622 shares (the “Additional Shares”) of Common Stock at the option of the Underwriters as provided in Section 2(c) below. The Firm Shares and any Additional Shares purchased by the Underwriters are referred to herein as the “Shares.” Citigroup Global Markets Inc. (“Citigroup”), Guggenheim Securities, LLC (“Guggenheim”) and Barclays Capital Inc. (“Barclays”) are each acting as representative (the “Representatives”) of t

AMENDMENT NO. 2 TO LETTER AGREEMENT
Letter Agreement • August 14th, 2019 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This Amendment No. 2 (“Amendment No. 2”) to the Development Program Letter Agreement of May 16, 2017 is entered into and effective as of August 1, 2019 (the “Amendment No. 2 Effective Date”) by and between Arcturus Therapeutics, Inc. (“Arcturus”) and the Cystic Fibrosis Foundation (“CFF”).

TECHNOLOGY LICENSE AND TECHNICAL SUPPORT AGREEMENT
License and Technical Support Agreement • August 10th, 2021 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This TECHNOLOGY LICENSE AND TECHNICAL SUPPORT AGREEMENT (this “Agreement”), with a signature date of the 29th day of July, 2021 (the “Signature Date”), is being entered into by and between Arcturus Therapeutics, Inc., a Delaware corporation (“Arcturus”), with its headquarters at 10628 Science Center Drive Suite 250, San Diego, CA 92121 and Vinbiocare Biotechnology Joint Stock Company, a company duly established under the laws of Vietnam (“Vinbiocare”), with its registered address at Techno Park office building, Vinhomes Ocean Park urban area, Da Ton commune, Gia Lam district, Hanoi, Vietnam. Arcturus and Vinbiocare may be referred to herein by name or individually, as a “Party” and collectively, as the “Parties.”

FRAMEWORK DRUG SUBSTANCE SUPPLY AGREEMENT
Drug Substance Supply Agreement • August 10th, 2021 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • England and Wales

This FRAMEWORK DRUG SUBSTANCE SUPPLY AGREEMENT (this “Agreement”), dated as of the 29th day of July, 2021 (the “Signature Date”), is being entered into by and between Arcturus Therapeutics, Inc., a Delaware corporation (“Arcturus”) with its headquarters at 10628 Science Center Drive, Suite 250 San Diego, CA 92121, and Vinbiocare Biotechnology Joint Stock Company a company duly established under the laws of Vietnam (“Vinbiocare”), with its registered address at Techno Park office building, Vinhomes Ocean Park urban area, Da Ton commune, Gia Lam district, Hanoi, Vietnam. Arcturus and Vinbiocare may be referred to herein by name or individually, as a “Party” and collectively, as the “Parties.”

THIRD AMENDMENT TO LEASE
Arcturus Therapeutics Holdings Inc. • March 1st, 2021 • Pharmaceutical preparations

THIS THIRD AMENDMENT TO LEASE (the "Amendment") is made this February 25, 2021 (the "Effective Date"), by and between ARE-SD REGION NO. 44, LLC, a Delaware limited liability company ("Landlord"), and ARCTURUS THERAPEUTICS, INC., a Delaware corporation ("Tenant").

FIFTH AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • November 9th, 2021 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This Fifth Amendment to Loan and Security Agreement (this “Amendment”) is entered into as of October 27, 2021, by and between WESTERN ALLIANCE BANK, an Arizona corporation (“Bank”), and ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Borrower”).

THE BOARDWALK LEASE
Boardwalk Lease • November 9th, 2021 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • California

This Lease (the “Lease”), dated as of the date set forth in Section 1 of the Summary of Basic Lease Information (the “Summary”), below, is made by and between TPSC IX, LLC, a Delaware limited liability company (“Landlord”), and ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Tenant”).

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FIRST AMENDMENT TO LEASE
Lease • March 16th, 2020 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

THIS FIRST AMENDMENT TO LEASE (this “First Amendment”) is made as of February 1, 2020, by and between ARE-SD REGION NO. 44, LLC, a Delaware limited liability company (“Landlord”), and ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Tenant”).

SECOND AMENDMENT TO LEASE
Lease • March 1st, 2021 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This SECOND Amendment to Lease (the “Amendment”) is made this ________________, 2020 (the “Effective Date”), by and between ARE-SD Region No. 44, LLC, a Delaware limited liability company (“Landlord”), and ARCTURuS THERAPEUTICS, INC., a Delaware corporation (“Tenant”).

THIRD AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • November 8th, 2019 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This Third Amendment to Loan and Security Agreement (this “Amendment”) is entered into as of October 30, 2019, by and between WESTERN ALLIANCE BANK, an Arizona corporation (“Bank”), and ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Borrower”).

Contract
Termination Agreement • August 14th, 2019 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York

This TERMINATION AGREEMENT (the “Termination Agreement”) is made as of July 26, 2019 (the “Effective Termination Date”), by and between Arcturus Therapeutics, Inc., a Delaware corporation with offices at 10628 Science Center Drive, Suite 200, San Diego, California 92121, U.S. (“Arcturus”), and CureVac AG, a German stock corporation with offices at Paul-Ehrlich-Strasse 15, 72076 Tuebingen, Germany (“CureVac”). CureVac and Arcturus are referred to in this Termination Agreement individually as a “Party” and collectively as the “Parties”.

CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [***], HAS BEEN OMITTED BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL. STUDY SUPPORT AGREEMENT
Study Support Agreement • November 4th, 2022 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • England and Wales

This Study Support Agreement (this “Agreement”) is made and entered into effective as of the 31st day of October, 2022 (the “Effective Date”), by and among Arcturus Therapeutics, Inc., a Delaware Corporation with offices at 10628 Science Center Drive, Suite 250, San Diego, CA 92121 (“ARCTURUS”), and Vinbiocare Biotechnology Joint Stock Company, a company duly established under the laws of Vietnam with its registered address at Lot CN1-12B-3- at Hi-Tech Industrial Park 1, Hoa Lac Hi-Tech Park, Thach Hoa, Thach That, Hanoi City, Vietnam (“VBC”). ARCTURUS and VBC are referred to herein as the “Parties.”

SIXTH AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • May 9th, 2022 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This Sixth Amendment to Loan and Security Agreement (this “Amendment”) is entered into as of April __, 2022, by and between WESTERN ALLIANCE BANK, an Arizona corporation (“Bank”), and ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Borrower”).

REDACTED Certain identified information, indicated by [***], has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm if publicly disclosed. Amendment number one to COLLABORATION AND LICENSE...
Collaboration and License Agreement • November 14th, 2023 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This Amendment Number One to Collaboration and License Agreement (this “Amendment”) is made and entered into on August 3, 2023 (the “Amendment Effective Date”) and amends the Collaboration Agreement by and between Arcturus Therapeutics, Inc., a Delaware corporation (“Arcturus”), and Seqirus Inc., a Delaware corporation (“Seqirus”). Arcturus and Seqirus are sometimes referred to herein individually as a “Party” and together as the “Parties.” Capitalized terms used in this Amendment that are not defined herein shall have the meanings ascribed to such terms in the Collaboration Agreement.

FOURTH AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • December 7th, 2020 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations

This Fourth Amendment to Loan and Security Agreement (this “Amendment”) is entered into as of December 1, 2020, by and between WESTERN ALLIANCE BANK, an Arizona corporation (“Bank”), and ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Borrower”).

ARCTURUS THERAPEUTICS HOLDINGS INC. AMENDMENT NO. 1 TO Controlled Equity OfferingSM Sales Agreement
Sales Agreement • August 7th, 2023 • Arcturus Therapeutics Holdings Inc. • Pharmaceutical preparations • New York
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