Organovo Holdings, Inc. Sample Contracts

9,000,000 Shares Organovo Holdings, Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • October 25th, 2016 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • New York

foregoing restrictions shall not apply to (i) the establishment of a trading plan pursuant to Rule 10b5-1 under the Exchange Act for the transfer of Shares or Related Securities, provided that (x) no public announcement or filing under the Exchange Act shall be permitted with respect to the establishment of such trading plan, and (y) such plan shall not provide for or permit any transfers, sales or other dispositions of Shares or Related Securities during the Lock-up Period, or (ii) the transfer of Shares or Related Securities by gift, or by will or intestate succession to a Family Member or to a trust whose beneficiaries consist exclusively of one or more of the undersigned and/or a Family Member; provided, however, that in the case of clause (ii), it shall be a condition to such transfer that:

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ORGANOVO HOLDINGS, INC., Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of , 20 Debt Securities
Indenture • January 19th, 2021 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • New York

INDENTURE, dated as of , 20 , by and between ORGANOVO HOLDINGS, INC., a Delaware corporation (the “Company”), and [TRUSTEE], as trustee (the “Trustee”):

ORGANOVO HOLDINGS, INC. Shares of Common Stock (par value $0.001 per share) Controlled Equity OfferingSM Sales Agreement
Organovo Holdings, Inc. • December 30th, 2014 • Biological products, (no disgnostic substances) • New York

Organovo Holdings, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cantor Fitzgerald & Co. (the “Agent”), as follows:

9,000,000 Shares of Common Stock par value $0.001 1,350,000 Over-Allotment Shares Organovo Holdings, Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • August 2nd, 2013 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • New York
LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • December 23rd, 2019 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances)

THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) dated as of March 29, 2019 (the “Effective Date”) among OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 hereof or otherwise a party hereto from time to time including Oxford in its capacity as a Lender (each a “Lender” and collectively, the “Lenders”), and TARVEDA THERAPEUTICS, INC., a Delaware corporation with an office located at 134 Coolidge Avenue, Watertown, Massachusetts 02472 (“Borrower”), provides the terms on which the Lenders shall lend to Borrower and Borrower shall repay the Lenders. The parties agree as follows:

ORGANOVO HOLDINGS, INC., ISSUER AND [TRUSTEE], TRUSTEE INDENTURE DATED AS OF , 20 SENIOR DEBT SECURITIES
Organovo Holdings, Inc. • July 17th, 2013 • Biological products, (no disgnostic substances) • New York

INDENTURE, dated as of [•], 20[•], among ORGANOVO HOLDINGS, INC., a Delaware corporation (the “Company”), and [TRUSTEE], as trustee (the “Trustee”):

LEASE by and between BMR-134 COOLIDGE AVENUE LLC, a Delaware limited liability company and BLEND THERAPEUTICS, INC. a Delaware corporation
Lease • December 23rd, 2019 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances)

THIS LEASE (this “Lease”) is entered into as of this 12th day of December, 2011 (the “Execution Date”), by and between BMR-134 COOLIDGE AVENUE LLC, a Delaware limited liability company (“Landlord”), and BLEND THERAPEUTICS, INC. a Delaware corporation (“Tenant”).

Organovo Holdings, Inc. 4,000,000 Shares of Common Stock EQUITY DISTRIBUTION AGREEMENT Dated: November 27, 2013
Equity Distribution Agreement • November 27th, 2013 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • New York
WARRANT TO PURCHASE SHARES of ORGANOVO, INC. Dated as of September [__], 2011 Void after the date specified in Section 8
Organovo Holdings, Inc. • February 13th, 2012 • Real estate operators (no developers) & lessors • California

THIS CERTIFIES THAT, for value received, [_____________], or its registered assigns (the “Holder”), is entitled, subject to the provisions and upon the terms and conditions set forth herein, to purchase from Organovo, Inc., a Delaware corporation (the “Company”), Shares (as defined below), in the amounts, at such times and at the price per share set forth in Section 1. The term “Warrant” as used herein shall include this Warrant and any warrants delivered in substitution or exchange therefor as provided herein. This Warrant is issued in connection with the transactions described in the Exchange Agreement and Release, dated as of September [__], 2011, by and among the Company and the purchasers described therein (the “Purchase Agreement”).

SPLIT-OFF AGREEMENT
Split-Off Agreement • February 13th, 2012 • Organovo Holdings, Inc. • Real estate operators (no developers) & lessors • Delaware

This SPLIT-OFF AGREEMENT, dated as of February 8, 2012 (this “Agreement”), is entered into by and among Organovo Holdings, Inc., a Delaware corporation (“Seller”), Organovo Split Corp., a Delaware corporation (“Split-Off Subsidiary”) and Deborah Lovig (“Buyer”).

ORGANOVO HOLDINGS, INC., ISSUER AND [TRUSTEE], TRUSTEE INDENTURE DATED AS OF , 20 SUBORDINATED DEBT SECURITIES
Organovo Holdings, Inc. • February 27th, 2015 • Biological products, (no disgnostic substances) • New York

INDENTURE, dated as of [•], 200 , among Organovo Holdings, INC., a Delaware corporation (the “Company”), and [TRUSTEE], as trustee (the “Trustee”):

Contract
Organovo Holdings, Inc. • January 29th, 2020 • Biological products, (no disgnostic substances) • New York

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE COMPANY, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

Contract
Organovo Holdings, Inc. • December 23rd, 2019 • Biological products, (no disgnostic substances) • Delaware

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR ANY APPLICABLE STATE SECURITIES LAWS, AND, EXCEPT AND PURSUANT TO THE PROVISIONS OF ARTICLE 4 BELOW, MAY NOT BE. OFFERED, SOLD OR OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS, OR PURSUANT TO RULE 144 OR AN EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS.

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • March 19th, 2012 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • New York

This Registration Rights Agreement (this “Agreement”) is made and entered into effective as of [insert], 201__ (the “Effective Date”) between Organovo Holdings, Inc., a Delaware corporation (the “Company”), and the persons who have executed the signature page(s) hereto (each, a “Purchaser” and collectively, the “Purchasers”).

Contract
Organovo Holdings, Inc. • December 23rd, 2019 • Biological products, (no disgnostic substances) • Delaware

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR ANY APPLICABLE STATE SECURITIES LAWS, AND, EXCEPT AND PURSUANT TO THE PROVISIONS OF ARTICLE 4 BELOW, MAY NOT BE. OFFERED, SOLD OR OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS, OR PURSUANT TO RULE 144 OR AN EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS.

First AMENDMENT TO AMENDED AND RESTATED lease BETWEEN SAN DIEGO INSPIRE 2, LLC, AS LANDLORD, AND ORGANOVO, INC., AS TENANT
Lease • November 19th, 2021 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • California

This Amended and Restated Lease (the “Lease”), dated as set forth in Section 1 of the Summary of Basic Lease Information (the “Summary”), for reference purposes only, is made by and between SAN DIEGO INSPIRE 2, LLC, a Delaware limited liability company (“Landlord”), and ORGANOVO, INC., a Delaware corporation (“Tenant”). By amending and restating in its entirety a certain Lease (the “Original Lease”) dated for reference purposes as of the same date as this Lease and replacing the original tenant, Organovo Holdings, Inc., a Delaware corporation, with Organovo, Inc., a Delaware corporation, Landlord and Tenant hereby amend and restate the Original Lease so that the tenant under this Lease is Organovo, Inc., a Delaware corporation, the operating entity, as opposed to Organovo Holdings, Inc., the holding company of Organovo, Inc. This Lease supercedes in its entirety the Original Lease.

LEASE SOVA SCIENCE DISTRICT SAN DIEGO INSPIRE 1, LLC,
Organovo Holdings, Inc. • November 25th, 2020 • Biological products, (no disgnostic substances) • California

This Lease (the “Lease”), dated as set forth in Section 1 of the Summary of Basic Lease Information (the “Summary”), for reference purposes only, is made by and between SAN DIEGO INSPIRE 1, LLC, a Delaware limited liability company, (“Landlord”), and ORGANOVA HOLDINGS, INC., a Delaware corporation (“Tenant”).

EXHIBIT A-2 FIRST AMENDMENT TO WARRANT TO PURCHASE COMMON STOCK
Purchase Common Stock • December 5th, 2012 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • New York

This First Amendment (the “Amendment”) to Warrant to Purchase Common Stock (the “Warrant”), is made and entered into effective as of November 16, 2012 (the “Effective Date”), by and between Organovo Holdings, Inc., a Delaware corporation (the “Company”) and the undersigned (the “Holder”). Capitalized terms used but not otherwise defined herein shall have the same meanings as set forth in the Warrant.

ORGANOVO HOLDINGS, INC. RESTRICTED STOCK UNIT AGREEMENT
Restricted Stock Unit Agreement • March 25th, 2021 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • Delaware

Unless otherwise defined herein, the terms defined in the Organovo Holdings, Inc. 2021 Inducement Equity Incentive Plan (the “Plan”) will have the same defined meanings in this Restricted Stock Unit Agreement (the “Award Agreement”), which includes the Notice of Restricted Stock Unit Grant (the “Notice of Grant”) and the Terms and Conditions of Restricted Stock Unit Grant, attached hereto as Exhibit A.

Contract
Off Agreement • February 13th, 2012 • Organovo Holdings, Inc. • Real estate operators (no developers) & lessors • California

THIS WARRANT AND THE UNDERLYING SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR UNDER THE SECURITIES LAWS OF ANY STATE. THESE SECURITIES MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR HYPOTHECATED EXCEPT AS PERMITTED UNDER THE ACT AND APPLICABLE STATE SECURITIES LAWS IN ACCORDANCE WITH APPLICABLE REGISTRATION REQUIREMENTS OR AN EXEMPTION THEREFROM. THE ISSUER OF THESE SECURITIES MAY REQUIRE AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO THE ISSUER THAT SUCH OFFER, SALE, TRANSFER, PLEDGE OR HYPOTHECATION OTHERWISE COMPLIES WITH THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS. THIS WARRANT MUST BE SURRENDERED TO THE COMPANY OR ITS TRANSFER AGENT AS A CONDITION PRECEDENT TO THE SALE, TRANSFER, PLEDGE OR HYPOTHECATION OF ANY INTEREST IN ANY OF THE SECURITIES REPRESENTED HEREBY.

SUPPORT AGREEMENT
Support Agreement • December 16th, 2019 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • Delaware

This SUPPORT AGREEMENT (this “Agreement”), dated as of December 13, 2019, is by and between Organovo Holdings, Inc., a Delaware corporation (“Organovo”), Tarveda Therapeutics, Inc. (the “Buyer”) and the undersigned holder (the “Stockholder”) of securities of Organovo.

ORGANOVO HOLDINGS, INC. STOCK OPTION AGREEMENT
Stock Option Agreement • March 25th, 2021 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • Delaware

Unless otherwise defined herein, the terms defined in the Organovo Holdings, Inc. 2021 Inducement Equity Incentive Plan (the “Plan”) will have the same defined meanings in this Stock Option Agreement (the “Agreement”), including the Notice of Stock Option Grant (the “Notice of Grant”) and Terms and Conditions of Stock Option Grant, attached hereto as Exhibit A.

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EXHIBIT A-3 FIRST AMENDMENT TO WARRANT TO PURCHASE SHARES
Organovo Holdings, Inc. • December 5th, 2012 • Biological products, (no disgnostic substances) • California

This First Amendment (the “Amendment”) to Warrant to Purchase Shares (the “Warrant”), is made and entered into effective as of November 16, 2012 (the “Effective Date”), by and between Organovo Holdings, Inc., a Delaware corporation (the “Company”) and the undersigned (the “Holder”). Capitalized terms used but not otherwise defined herein shall have the same meanings as set forth in the Warrant.

EMPLOYMENT AGREEMENT
Employment Agreement • December 23rd, 2019 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • Massachusetts

This Employment Agreement (this “Agreement’,) dated as of July 27, 2018 (the “Effective Date”), is made by and between Tarveda Therapeutics, Inc., a Delaware corporation formerly named Blend Therapeutics, Inc., (the “Company” or “Tarveda”), and Jeffrey Bloss (“Executive”).

Separation Agreement and General Release
Separation Agreement and General Release • September 22nd, 2023 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • California

This Separation Agreement and General Release (“Agreement”) is entered into by and between Jeff Miner (Employee) and Organovo, Inc. (“Company”). The Employee’s Company employment ended on August 25, 2023 (Separation Date). The “Effective Date” of this Agreement will be the eighth day following the date that the Employee signs and returns this Agreement to the Company provided the Employee does not rescind this Agreement in the seven days following the date that the Employee signs it.

ORGANOVO HOLDINGS, INC. INCENTIVE AWARD STOCK OPTION AGREEMENT
Award Agreement • August 14th, 2018 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • Delaware

In accordance with the terms of the offer letter, dated June 28, 2018, by and between Organovo Holdings, Inc. (the “Company”) and Steven G. Hughes, M.D. (“Participant”), the Compensation Committee of the Board of Directors has granted the Participant a Stock Option (the “Option”) represented by this Incentive Award Stock Option Agreement (the “Award Agreement”) as of the Date of Grant below.

ORGANOVO HOLDINGS, INC.
Stock Option Award Agreement • June 9th, 2015 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • Delaware

Unless otherwise defined herein, the terms defined in the Organovo Holdings, Inc. 2012 Equity Incentive Plan (the “Plan”) will have the same defined meanings in this Stock Option Award Agreement (the “Award Agreement”), except as provided in a Superseding Agreement (as defined below).

LICENSE AGREEMENT
License Agreement • May 11th, 2012 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • Missouri

THIS AGREEMENT is made and entered into this 12th day of March, 2010 (“EFFECTIVE DATE”), by and between THE CURATORS OF THE UNIVERSITY OF MISSOURI, a public corporation of the State of Missouri having a principal office at The Office of Technology Management & Industry Relations, 340 Bond Life Sciences Center, Columbia, MO 65211, (“UNIVERSITY”) and Organovo having offices at 5871 Oberlin Dr., Suite 150, San Diego, CA 92121 (“LICENSEE”).

FOURTH AMENDMENT TO LEASE
Lease • December 23rd, 2019 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances)

THIS FOURTH AMENDMENT TO LEASE (this “Amendment”) is entered into as of this 31st day of May, 2019, by and between BMR-134 COOLIDGE AVENUE LLC, a Delaware limited liability company (“Landlord”), and TARVEDA THERAPEUTICS, INC. (formerly known as Blend Therapeutics, Inc.), a Delaware corporation (“Tenant”).

Thomas E. Jurgensen tom@optimalawgroup.com 858.946.4697
Organovo Holdings, Inc. • November 5th, 2020 • Biological products, (no disgnostic substances)

Re:Engagement Agreement between Optima Law Group, APC and Organovo Holdings, Inc., and its subsidiaries (hereinafter, “Agreement”)

AGREEMENT AND PLAN OF MERGER AND REORGANIZATION AMONG ORGANOVO HOLDINGS, INC., a Delaware corporation ORGANOVO ACQUISITION CORP., a Delaware corporation AND ORGANOVO, INC., a Delaware corporation February 8, 2012
Agreement and Plan of Merger and Reorganization • February 13th, 2012 • Organovo Holdings, Inc. • Real estate operators (no developers) & lessors • Delaware

AGREEMENT AND PLAN OF MERGER (this “Agreement”), dated as of February 8, 2012, by and among Organovo Holdings, Inc. (f/k/a Real Estate Restoration and Rental, Inc.), a Delaware corporation (the “Parent”), Organovo Acquisition Corp., a Delaware corporation (the “Acquisition Subsidiary”) and Organovo, Inc., a Delaware corporation (the “Company”). The Parent, the Acquisition Subsidiary and the Company are each a “Party” and referred to collectively herein as the “Parties.”

ORGANOVO HOLDINGS, INC. GLOBAL RESTRICTED STOCK UNIT AWARD AGREEMENT
Restricted Stock Unit Award Agreement • October 25th, 2022 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • Delaware

Unless otherwise defined herein, the terms defined in the Organovo Holdings, Inc., 2022 Equity Incentive Plan (the “Plan”) will have the same defined meanings in this Global Restricted Stock Unit Award Agreement, the Terms and Conditions of the Global Restricted Stock Unit Grant, attached hereto as Exhibit A and the Addendum, attached hereto as Exhibit B, all of which are made a part of this document (together, the “Award Agreement”).

CONSULTING, SEPARATION AGREEMENT AND RELEASE
Consulting, Separation Agreement and Release • April 5th, 2016 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • California

This Consulting, Separation Agreement and Release (“Agreement”) is made by and between Barry Michaels (“Employee”) and Organovo Holdings, Inc., a Delaware corporation, and its wholly-owned subsidiary, Organovo, Inc., a Delaware corporation (Organovo Holdings, Inc. and Organovo, Inc., shall be collectively referred to herein as, the “Company”). Employee and the Company shall collectively be referred to herein as the “Parties”, and each individually as a “Party.”

ESCROW DEPOSIT AGREEMENT
Escrow Deposit Agreement • March 19th, 2012 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • New York

This ESCROW DEPOSIT AGREEMENT (this “Agreement”) dated this 19th day of September, 2011, by and among ORGANOVO, INC., a Delaware corporation (the “Company”), having an address at 5871 Oberlin Drive, Suite 150, San Diego, CA 92121, SPENCER TRASK VENTURES, INC., a Delaware corporation, registered broker-dealer and a member of the Financial Industry Regulatory Authority, Inc. (“Spencer Trask” or the “Selling Agent”), having an address at 750 Third Avenue, 11th Floor, New York, New York 10017 and SIGNATURE BANK (the “Escrow Agent”), a New York State chartered bank, having an office at 261 Madison Avenue, New York, New York 10016. All capitalized terms not herein defined shall have the meaning ascribed to them in that certain Confidential Information Memorandum, dated September 19, 2011, as amended or supplemented from time-to-time, including all attachments, schedules and exhibits thereto (the “Memorandum”).

JOINDER AGREEMENT
Joinder Agreement • March 19th, 2012 • Organovo Holdings, Inc. • Biological products, (no disgnostic substances) • New York

This JOINDER AGREEMENT (the “Joinder” or the “Agreement”), dated as of January 23, 2012, by and among Spencer Trask Ventures, Inc., a Delaware corporation, and a registered broker-dealer and member of the Financial Industry Regulatory Authority (“STV”), Organovo, Inc., a Delaware corporation (“Organovo”), Organovo Holdings, Inc., a Nevada corporation (“Pubco”) and Signature Bank (the “Escrow Agent”), a New York State chartered bank. Capitalized terms used herein but not otherwise defined shall have the meanings set forth in the Escrow Deposit Agreement (as defined below).

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