Esperion Therapeutics, Inc. Sample Contracts

COMMON STOCK PURCHASE WARRANT
Common Stock Purchase Warrant • December 7th, 2021 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date set forth above (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on December 7, 2023 (the “Termination Date”) but not thereafter, to subscribe for and purchase from Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of the Company’s Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • March 22nd, 2023 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of March 19, 2023, between Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

UNDERWRITING AGREEMENT Esperion Therapeutics, Inc. 3,100,000 Shares of Common Stock Underwriting Agreement
Underwriting Agreement • August 10th, 2017 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters listed in Schedule 1 hereto (the “Underwriters”), for whom you are acting as representatives (the “Representatives”), an aggregate of 3,100,000 shares of common stock, par value $0.001 per share (the “Common Stock”), of the Company (the “Underwritten Shares”) and, at the option of the Underwriters, up to an additional 465,000 shares of Common Stock of the Company (the “Option Shares”). The Underwritten Shares and the Option Shares are herein referred to as the “Shares.” The shares of Common Stock of the Company to be outstanding after giving effect to the sale of the Shares are referred to herein as the “Stock.”

ESPERION THERAPEUTICS, INC., Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [●], 202[●] Senior Debt Securities
Indenture • April 18th, 2025 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

INDENTURE, dated as of [●], 202[●] , among ESPERION THERAPEUTICS, INC., a Delaware corporation (the “Company”), and [TRUSTEE] as trustee (the “Trustee”):

56,700,000 Shares Esperion Therapeutics, Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • January 22nd, 2024 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

Introductory. Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters named in Schedule A (the “Underwriters”) an aggregate of 56,700,000 shares of its common stock, par value $0.001 per share (the “Shares”). The 56,700,000 Shares to be sold by the Company are called the “Firm Shares.” In addition, the Company has granted to the Underwriters an option to purchase up to an additional 8,505,000 Shares as provided in Section 2. The additional 8,505,000 Shares to be sold by the Company pursuant to such option are collectively called the “Optional Shares.” The Firm Shares and, if and to the extent such option is exercised, the Optional Shares are collectively called the “Offered Shares.” Jefferies LLC (“Jefferies”) has agreed to act as representative of the several Underwriters (in such capacity, the “Representative”) in connection with the offering and sale of the Offered Shares. To the extent there are no additional under

ESPERION THERAPEUTICS, INC. AND U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of December 17, 2024 5.75% Convertible Senior Subordinated Notes due 2030
Indenture • December 18th, 2024 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

INDENTURE dated as of December 17, 2024, between ESPERION THERAPEUTICS, INC., a Delaware corporation, as issuer (the “Company”, as more fully set forth in ‎Section 1.01) and U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”, as more fully set forth in ‎Section 1.01).

PRE-FUNDED COMMON STOCK PURCHASE WARRANT ESPERION THERAPEUTICS, INC.
Pre-Funded Common Stock Purchase Warrant • March 22nd, 2023 • Esperion Therapeutics, Inc. • Pharmaceutical preparations

THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date set forth above (the “Initial Exercise Date”) and until this Warrant is exercised in full (the “Termination Date”) but not thereafter, to subscribe for and purchase from Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

COMMON STOCK PURCHASE WARRANT Esperion Therapeutics, Inc.
Common Stock Purchase Warrant • March 22nd, 2023 • Esperion Therapeutics, Inc. • Pharmaceutical preparations

THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date set forth above (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on ______________ (the “Termination Date”) but not thereafter, to subscribe for and purchase from Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

OPEN MARKET SALE AGREEMENT
Open Market Sale Agreement • August 3rd, 2021 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell from time to time through Jefferies LLC, as sales agent and/or principal (the “Agent”), shares of the Company’s common stock, par value $0.001 per share (the “Common Shares”), having an aggregate offering price of up to $250,000,000 on the terms set forth in this agreement (this “Agreement”).

•] Shares Esperion Therapeutics, Inc. Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • June 12th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York
ESPERION THERAPEUTICS, INC. FORM OF OFFICER INDEMNIFICATION AGREEMENT
Indemnification Agreement • April 12th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (“Agreement”) is made as of by and between Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”).

ESPERION THERAPEUTICS, INC. FORM OF DIRECTOR INDEMNIFICATION AGREEMENT
Director Indemnification Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (“Agreement”) is made as of by and between Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”).

ESPERION THERAPEUTICS, INC. FORM OF OFFICER INDEMNIFICATION AGREEMENT
Officer Indemnification Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (“Agreement”) is made as of by and between Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”).

HDL THERAPEUTICS, INC. INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Delaware

THIS INVESTOR RIGHTS AGREEMENT (the “Agreement”) is entered into as of the 28th day of April 2008, by and among HDL Therapeutics, Inc., a Delaware corporation (the “Company”) and the investors listed on Exhibit A hereto, referred to hereinafter as the “Investors” and each individually as an “Investor.”

Esperion Therapeutics, Inc. Shares of Common Stock (par value $0.001 per share) Controlled Equity OfferingSM Sales Agreement
Sales Agreement • February 21st, 2023 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York
EMPLOYMENT AGREEMENT
Employment Agreement • November 16th, 2022 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Michigan

This Employment Agreement (“Agreement”) is made as of the 16th day of November, 2022, by and between Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), and Benjamin Halladay (the “Executive”). Except with respect to the Restrictive Covenants (as defined below), this Agreement supersedes, amends and restates in all respects all prior agreements between the Executive and the Company regarding the subject matter herein.

CREDIT AGREEMENT Dated as of December 13, 2024 among ESPERION THERAPEUTICS, INC., as the Borrower, CERTAIN SUBSIDIARIES OF THE BORROWER, as the Guarantors, GLAS USA LLC and GLAS AMERICAS LLC, as the Administrative Agent and THE LENDERS FROM TIME TO...
Credit Agreement • December 13th, 2024 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

This CREDIT AGREEMENT is entered into as of December 13, 2024 among ESPERION THERAPEUTICS, INC., a Delaware corporation (the “Borrower”), the Guarantors (defined herein) from time to time party hereto, the Lenders (defined herein) and GLAS USA LLC, a limited liability company organized and existing under the laws of the State of New Jersey, and GLAS Americas LLC, a limited liability company organized and existing under the laws of the State of New York, collectively as the Administrative Agent.

Esperion Therapeutics, Inc. 32,142,858 Shares of Common Stock (par value $0.001 per share) No Pre-Funded Warrants to Purchase Shares of Common Stock and Warrants to Purchase 32,142,858 Shares of Common Stock Underwriting Agreement
Underwriting Agreement • December 7th, 2021 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

Esperion Therapeutics, Inc., a company incorporated under the laws of the State of Delaware (the “Company”), proposes to issue and sell to the several underwriters named in Schedule A (the “Underwriters”) (i) an aggregate of (a) 32,142,858 shares of its common stock, par value $0.001 per share (the “Shares”), and (b) no pre-funded warrants (the “Pre-Funded Warrants”) to purchase shares of Common Stock, as such term is defined herein, at an exercise price of $0.01 per share and (ii) common stock warrants to purchase 32,142,858 shares of Common Stock (the “Common Warrants”). The 32,142,858 Shares to be sold by the Company are called the “Firm Shares” and, collectively with the Pre-Funded Warrants and the Common Warrants, the “Firm Securities.” In addition, the Company has granted to the Underwriters an option to purchase up to an additional 4,821,428 Shares (collectively, the “Optional Shares”) and/or Common Warrants to purchase up to an aggregate of 4,821,428 shares of Common Stock (the

EMPLOYMENT AGREEMENT
Employment Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Michigan

THIS EMPLOYMENT AGREEMENT (this “Agreement”) by and between ESPERION THERAPEUTICS, INC., a Delaware corporation (the “Company”) and ROGER NEWTON (“Executive”) is made and entered into on December 4, 2012 to be effective as of December 10, 2012 (the “Effective Date”).

WARRANT TO PURCHASE PREFERRED STOCK
Warrant Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Michigan

This Warrant is being issued as one of a series of warrants pursuant to the terms of the Convertible Note and Warrant Purchase Agreement, dated as of September 4, 2012, by and among the Company and the purchasers therein (the “Purchase Agreement”). Capitalized terms not otherwise defined herein shall have the meaning given to such terms in the Purchase Agreement. Unless indicated otherwise, the number and type of shares of capital stock of the Company that Holder may purchase by exercising this Warrant is as follows:

REVENUE INTEREST PURCHASE AGREEMENT dated as of June 26, 2019 among ESPERION THERAPEUTICS, INC., the Purchasers from time to time party hereto and Eiger III SA LLC, as Purchaser Agent
Revenue Interest Purchase Agreement • June 26th, 2019 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

This REVENUE INTEREST PURCHASE AGREEMENT (as amended, supplemented or otherwise modified from time to time, this “Agreement”) is made and entered into as of June 26, 2019, by and among Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), the Purchasers from time to time party hereto (each, a “Purchaser” and collectively, the “Purchasers”) and Eiger III SA LLC, as collateral agent and administrative agent for the Purchasers (the “Purchaser Agent”).

From: Morgan Stanley & Co. LLC 1585 Broadway, 5th Floor New York, NY 10036 To: Esperion Therapeutics, Inc. 3891 Ranchero Drive, Suite 150 Ann Arbor, MI 48108 Re: Forward Stock Purchase Transaction
Forward Stock Purchase Transaction • November 16th, 2020 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

The purpose of this letter agreement (this “Confirmation”) is to confirm the terms and conditions of the transaction entered into between Morgan Stanley & Co. LLC (“Dealer”) and Esperion Therapeutics, Inc. (“Issuer” or “Counterparty”) on the Trade Date specified below (the “Transaction”). This letter agreement constitutes a “Confirmation” as referred to in the ISDA Master Agreement specified below. This Confirmation shall replace any previous agreements and serve as the final documentation for the Transaction.

CERTAIN CONFIDENTIAL INFORMATION, MARKED BY [***] HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS BOTH NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL. ROYALTY PURCHASE AGREEMENT ESPERION THERAPEUTICS, INC. as...
Royalty Purchase Agreement • August 12th, 2024 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

AND WHEREAS Seller desires to sell, transfer, assign and convey to Purchaser, and Purchaser desires to purchase, acquire and accept from Seller, Seller’s right, title and interest in and to the Purchased Receivables, upon and subject to the terms and conditions set forth in this Agreement;

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • July 2nd, 2014 • Esperion Therapeutics, Inc. • Pharmaceutical preparations

THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) dated as of June 30, 2014 (the “Effective Date”) among OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 hereof or otherwise a party hereto from time to time including Oxford in its capacity as a Lender (each a “Lender” and collectively, the “Lenders”), and ESPERION THERAPEUTICS, INC., a Delaware corporation with an office located at 3891 Ranchero Drive, Suite 150, Ann Arbor, MI 48108 (“Borrower”), provides the terms on which the Lenders shall lend to Borrower and Borrower shall repay the Lenders. The parties agree as follows:

HDL THERAPEUTICS, INC. REGISTRATION RIGHTS AND SECURITYHOLDER AGREEMENT
Registration Rights and Securityholder Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Delaware

THIS REGISTRATION RIGHTS AND SECURITYHOLDER AGREEMENT (the “Agreement”) is entered into as of the 28th day of April 2008, by and between HDL Therapeutics, Inc., a Delaware corporation (the “Company”) and Pfizer, Inc., referred to hereinafter as “Investor.”

LICENSE AGREEMENT between PFIZER, INC. and ESPERION THERAPEUTICS, INC.
License Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

THIS LICENSE AGREEMENT (this “Agreement”), dated as of April 28, 2008 (the “Effective Date”), as amended on November 17, 2010, is by and between Esperion Therapeutics, Inc., a Delaware corporation (“Esperion”), and Pfizer, Inc., a Delaware corporation (“Pfizer”). Esperion and Pfizer are individually referred to herein as a “Party”, and collectively referred to herein as the “Parties”.

FIRST AMENDMENT TO LEASE
Lease • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Michigan

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AMENDMENT NO. 1 TO INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This Amendment No. 1 to Investor Rights Agreement (this “Amendment”) is made as of April 11, 2013, by and among Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), those certain Key Holders of the Company’s Common Stock listed on the signature pages hereto (the “Key Holders”) and the Investors listed on the signature pages hereto (the “Investors”).

January 13, 2012 BY EMAIL Noah Rosenberg, M.D. ADDRESS Re: Executive Employment Agreement Dear Noah:
Executive Employment Agreement • May 14th, 2013 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Michigan

On behalf of Esperion Therapeutics, Inc. (the “Company”), I am pleased to offer you the position of the Company’s Chief Medical Officer (“CMO”). The terms and conditions of your employment are set forth in this Executive Employment Agreement (“Agreement”).

CONTINGENT VALUE RIGHTS AGREEMENT By and among ESSENCE PARENT INC., ESPERION THERAPEUTICS, INC. and COMPUTERSHARE INC. and COMPUTERSHARE TRUST COMPANY, N.A. acting jointly as, Rights Agent Dated as of July 13, 2026
Contingent Value Rights Agreement • July 13th, 2026 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This CONTINGENT VALUE RIGHTS AGREEMENT, dated as of July 13, 2026 (this “Agreement”), by and among Essence Parent Inc., a Delaware corporation (“Parent”), Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), and , Computershare Inc., a Delaware corporation (“Computershare”) and its affiliate, Computershare Trust Company, N.A., a federally chartered trust company (“Computershare Trust Company”), acting jointly with Computershare, as rights agent (the “Rights Agent”).

INDICATES MATERIAL THAT HAS BEEN OMITTED AND FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED. ALL SUCH OMITTED MATERIAL HAS BEEN FILED WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO RULE 24b-2 PROMULGATED UNDER THE SECURITIES EXCHANGE ACT...
License and Collaboration Agreement • August 10th, 2020 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

THIS LICENSE AND COLLABORATION AGREEMENT (this “Agreement”), entered into as of April 17, 2020 (the “Effective Date”), is entered into by and between Otsuka Pharmaceutical Co., Ltd., a corporation organized and existing under the laws of Japan (“Otsuka”) and Esperion Therapeutics, Inc., a corporation organized and existing under the laws of the state of Delaware, United States (“Esperion”).

December 8, 2016 Roger Newton Re: Scientific Advisor Agreement Dear Roger:
Scientific Advisor Agreement • December 9th, 2016 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • Michigan

This letter agreement documents our understanding regarding your decision to transition into a new role at Esperion Therapeutics, Inc. (the “Company”). We appreciate your contributions and we share your desire for a smooth and mutually beneficial transition plan. With that in mind, by signing below you and the Company agree as follows:

30,000,000 Shares Esperion Therapeutics, Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • October 8th, 2025 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York
SECOND SUPPLEMENTAL INDENTURE
Second Supplemental Indenture • July 13th, 2026 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

This Second Supplemental Indenture (this “Supplemental Indenture”) is made and entered into as of July 13, 2026, among Esperion Therapeutics, Inc., a Delaware corporation (the “Company”), Essence Parent Inc., a Delaware corporation (“Parent”), and U.S. Bank Trust Company, National Association, as trustee (the “Trustee”).

INDICATES MATERIAL THAT HAS BEEN OMITTED AND FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED. ALL SUCH OMITTED MATERIAL HAS BEEN FILED WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO RULE 24b-2 PROMULGATED UNDER THE SECURITIES EXCHANGE ACT...
License and Collaboration Agreement • February 28th, 2019 • Esperion Therapeutics, Inc. • Pharmaceutical preparations • New York

THIS LICENSE AND COLLABORATION AGREEMENT (this “Agreement”), entered into as of January 2, 2019 (the “Effective Date”), is entered into by and between Daiichi Sankyo Europe GmbH, a corporation organized and existing under the laws of Germany (“DSE”) and Esperion Therapeutics, Inc., a corporation organized and existing under the laws of the state of Delaware (“Esperion”).