0001193125-26-328889 Sample Contracts

CERTAIN INFORMATION IDENTIFIED WITH [***] HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS (1) NOT MATERIAL AND (2) OF THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL. RESEARCH COLLABORATION AND LICENSE AGREEMENT BY AND AMONG ELI LILLY...
Research Collaboration and License Agreement • July 31st, 2026 • TRex Bio, Inc. • Biological products, (no disgnostic substances) • New York

This Research Collaboration and License Agreement (this “Agreement”) is entered into as of January 6, 2023 (the “Execution Date”) and is effective as of the Antitrust Clearance Date (the “Effective Date”) except for Article 9 hereof, which shall be effective as of the Execution Date, by and among, on the one hand, Eli Lilly and Company, an Indiana corporation (“Lilly”), and, on the other hand, TRex Bio Inc., a Delaware company (“TRex”), and solely for purposes of Section 14.9, TRex Holdings Inc., a Delaware company (“Parent”). Lilly and TRex are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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Re: Employment Agreement Dear Laura:
Employment Agreement • July 31st, 2026 • TRex Bio, Inc. • Biological products, (no disgnostic substances) • California

Trex Bio, Inc., a Delaware corporation (the “Company”), is pleased to offer you continued employment pursuant to the following terms (this “Agreement”):

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FIRST AMENDMENT TO RESEARCH COLLABORATION AND LICENSE AGREEMENT
Research Collaboration and License Agreement • July 31st, 2026 • TRex Bio, Inc. • Biological products, (no disgnostic substances)

This First Amendment to the Research Collaboration and License Agreement (this “First Amendment”), dated as of [XX], 2026 (“First Amendment Effective Date”), is made by and between Eli Lilly and Company, an Indiana corporation (“Lilly”), and TRex Bio, Inc., a Delaware corporation (“TRex”). Lilly and TRex are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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TRex Bio, Inc. Executive Employment Agreement
Executive Employment Agreement • July 31st, 2026 • TRex Bio, Inc. • Biological products, (no disgnostic substances) • California

This Executive Employment Agreement (the “Agreement”) made between TRex Bio, Inc, a Delaware corporation (the “Company”) and M. Johnston Erwin. Jr. (the “Executive” and, collectively with the Company the “Parties”), is entered into as of the date Executive commences his employment with the Company (the “Effective Date”).

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TRex Bio, Inc. South San Francisco, CA 94080 AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • July 31st, 2026 • TRex Bio, Inc. • Biological products, (no disgnostic substances) • Delaware

This Amendment to Employment Agreement (the “Amendment”) amends the Employment Agreement by and between TRex Bio, Inc., a Delaware corporation (the “Company”) and M. Johnston Erwin, Jr. (the “Executive”), (the “Employment Agreement”). This Amendment shall be effective as of June 22, 2026. All capitalized terms used in this Amendment shall have the meanings ascribed to them in the Employment Agreement unless otherwise expressly provided herein.

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