0001193125-11-066190 Sample Contracts

EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations • Oregon

THIS EMPLOYMENT AGREEMENT (“Agreement”) is made on this 24th day of July, 2008 (the “Effective Date”), by and between AVI BioPharma, Inc., an Oregon corporation, with its principal office at I S.W. Columbia Street, Suite 1100, Portland, Oregon 97258 (“Company”), and J. David Boyle II, 5329 Broadway, Oakland, CA 94618 (“Employee”).

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SCHNITZER NORTH CREEK LEASE AGREEMENT S/I NORTH CREEK VII, LLC (Landlord) and AVI BIOPHARMA, INC. (Tenant) Dated: October 20, 2010
Lease Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

THIS LEASE (“Lease”) is dated for reference purposes as of the 20th day of October, 2010, by and between S/I North Creek VII LLC, a Washington limited liability company (“Landlord”), and AVI BioPharma, Inc., an Oregon corporation (“Tenant”).

AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

This Amendment No. 2 to Employment Agreement (the “Amendment”) is entered into effective the day of 3rd day of November, 2009 (the “Effective Date”) by and between AVI BioPharma, Inc., an Oregon corporation (“Company”) and J. David Boyle II (“Employee”).

AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

This Amendment No. 1 to Employment Agreement (the “Amendment”) is entered into effective the 16th day of October, 2009 (the “Effective Date”) by and between AVI BioPharma, Inc., an Oregon corporation (“Company”) and Stephen Bevan Shrewsbury, MD (“Employee”).

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

THIS AMENDMENT (““Amendment”) TO THE EMPLOYMENT AGREEMENT (“Agreement”) dated July 14, 1997 is made on this 28th day of December, 2008 (the “Effective Date”), by and between AVI BioPharma, Inc., an Oregon corporation, with its principal office at 1 SW Columbia Street, Suite 1105, Portland, OR 97258 (“Company”), and Patrick Iversen, Ph.D. (“Employee”).

AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

This Amendment No. 2 to Employment Agreement (the “Amendment”) is entered into effective the 19th day of January, 2010 (the “Effective Date”) by and between AVI BioPharma, Inc., an Oregon corporation (“Company”) and Dwight Weller, Ph.D. (“Employee”).

AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

This Amendment No. 2 to Employment Agreement (the “Amendment”) is entered into effective the 18 day of January, 2010 (the “Effective Date”) by and between AVI BioPharma, Inc., an Oregon corporation (“Company”) and Patrick Iversen, Ph.D. (“Employee”).

EMPLOYMENT AGREEMENT
Stock Option Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations • Washington

THIS EMPLOYMENT AGREEMENT (“Agreement”) is made on this 15th day of May, 2009, by and between AVI BioPharma, Inc., an Oregon corporation, with its principal office at 4575 SW Research Way, Suite 200, Corvallis, Oregon, (“Company”), and Paul Medeiros, 700 Mixsell Street, Easton, Pennsylvania 18042 (“Employee”).

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

THIS AMENDMENT (““Amendment”) TO THE EMPLOYMENT AGREEMENT (“Agreement”) dated November 4, 1996 is made on this 28th day of December, 2008 (the “Effective Date”), by and between AVI BioPharma, Inc., an Oregon corporation, with its principal office at 1 SW Columbia Street, Suite 1105, Portland, OR 97258 (“Company”), and Dwight Weller, Ph.D. (“Employee”).

AVI BIOPHARMA, INC. EXECUTIVE EMPLOYMENT AGREEMENT
Avi Biopharma • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations • Washington

This Employment Agreement (the “Agreement”) is entered into as of December 17, 2010 (the “Effective Date”) by and between AVI BioPharma, Inc. (the “Company”), and Chris Garabedian (“Executive”).

LEASE EXTENSION AND MODIFICATION AGREEMENT
Lease Extension and Modification Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

This Lease Extension and Modification Agreement (“Agreement” is entered into and effective as of the 1st day of September, 1996, by and between Research Way Investments, a California limited partnership (“Landlord”) and AntiVirals, Inc. (“Tenant”).

AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

This Amendment No. 1 to Employment Agreement (the “Amendment”) is entered into effective the 16th day of October, 2009 (the “Effective Date”) by and between AVI BioPharma, Inc., an Oregon corporation (“Company”) and Ryszard Kole, Ph.D. (“Employee”).

AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

This Amendment No. 1 to Employment Agreement (the “Amendment”) is entered into effective the 16th day of October 2009 (the “Effective Date”) by and between AVI BioPharma, Inc., an Oregon corporation (“Company”) and Paul Medeiros (“Employee”).

AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2011 • Avi Biopharma Inc • Pharmaceutical preparations

This Amendment No. 1 to Employment Agreement (the “Amendment”) is entered into effective the 1st day of August, 2008 (the “Effective Date”) by and between AVI BioPharma, Inc., an Oregon corporation (“Company”) and J. David Boyle II (“Employee”).

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