0001144204-16-094827 Sample Contracts

LEASE AGREEMENT
Lease Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

THIS LEASE AGREEMENT (this “Lease”) is made this 9th day of February, 2010, between ARE-SEATTLE NO. 10, LLC, a Delaware limited liability company (“Landlord”), and PHASERX INC., a Delaware corporation (“Tenant”).

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NONQUALIFIED STOCK OPTION AGREEMENT PHASERX, INC.
Nonqualified Stock Option Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations • Delaware
PHASERX, INC. INDEMNIFICATION AGREEMENT
Indemnification Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (this “Agreement”) is entered into as of [month, day], 2014, by and between PhaseRx, Inc., a Delaware corporation (the “Corporation”), and [_______](“Indemnitee”).

PHASERX, INC. SECOND AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT November 17, 2014
Investors’ Rights Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations • Delaware

This Second Amended and Restated Investors’ Rights Agreement (this “Agreement”) is made as of November 17, 2014, by and among PhaseRx, Inc., a Delaware corporation (the “Company”), the persons and entities (each, a “Series A Investor”) listed on Exhibit A hereto, the persons and entities (each, a “Series A-1 Investor” and together with the Series A Investors, the “Investors”) listed on Exhibit A-1 hereto and the persons (each, a “Founder” and collectively, the “Founders”) listed on Exhibit B hereto. The Founders and Investors are referred to herein collectively as the “Stockholders.” Unless otherwise defined herein, capitalized terms used in this Agreement have the meanings ascribed to them in Section 1 hereof.

REGISTRATION RIGHTS AGREEMENT
Phaserx Registration Rights Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

This Registration Rights Agreement (this “Agreement”) is made and entered into as of February 29, 2016, among PhaseRx, Inc., a Delaware corporation (the “Company”), and each of the several lenders signatory hereto (each such lender, a “Lender” and, collectively, the “Lenders”).

PHASERX, INC. CONSULTING AGREEMENT
Consulting Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

This Consulting Agreement (“Agreement”) is entered into as of July 2, 2013 (the “Effective Date”) between PhaseRx, Inc., a Delaware corporation having a place of business at 410 West Harrison Street, Seattle, WA 98119 (“Company”) and Paul H. Johnson, Ph.D., having a place of business at 12020 211th Place SE Snohomish, Washington 98296 (“Consultant”). Company desires to retain Consultant to perform certain consulting activities as described below, and Consultant desires to serve as a consultant to Company and perform such activities under the terms of this Agreement.

LEASE AGREEMENT
Lease Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

THIS LEASE AGREEMENT (this “Lease”) is made this 9th day of February, 2010, between ARE-SEATTLE NO. 10, LLC, a Delaware limited liability company (“Landlord”), and PHASERX INC., a Delaware corporation (“Tenant”).

FIRST AMENDMENT TO LEASE
Lease • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

THIS FIRST AMENDMENT TO LEASE (this "First Amendment") is made as of July 1, 2010, by and between ARE-SEATTLE NO. 10, LLC, a Delaware limited liability company ("Landlord"), and PHASERX INC., a Delaware corporation ("Tenant").

AMENDMENT TO AMENDED AND RESTATED OFFER LETTER AGREEMENT
Offer Letter Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

This Amendment to Amended and Restated Offer Letter Agreement (this “Amendment”) is made and entered into as of the 13th day of March, 2016, by and between PhaseRx, Inc., a Delaware corporation, having a place of business at 410 West Harrison Street, Seattle, WA 98119 (the “Company”), and Robert W. Overell, Ph.D., having a place of business at 1854 NW 195th St. #302, Shoreline, WA 98177 (the “Executive”).

PHASERX, INC. AMENDMENT NO. 2 TO AMENDED AND RESTATED CONSULTING AGREEMENT
Consulting Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations • Washington

This Amendment No. 2 to Amended and Restated Consulting Agreement (this “Amendment”), is entered into effective as of April 1, 2012 and amends the terms of the Amended and Restated Consulting Agreement dated February 22, 2008 (the “Agreement”) as later amended pursuant to the a First Amendment entered into on June 1, 2011 (the “First Amendment”), between PhaseRx, Inc., a Delaware corporation (“Company”) and John A. Schmidt, Jr., M.D. LLC (“Consultant”). Capitalized terms not defined in this Amendment have the meanings set forth in the Agreement.

THIRD AMENDMENT TO LEASE
Lease • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

THIS THIRD AMENDMENT TO LEASE (this "Third Amendment") is made as of September 8, 2015, by and between ARE-SEATTLE NO. 10, LLC, a Delaware limited liability company ("Landlord"), and PHASERX INC., a Delaware corporation ("Tenant").

AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations • Delaware

This Amendment to Loan and Security Agreement (this “Amendment”) is made as of April 6, 2016, by and among PhaseRx, Inc., a Delaware corporation (the “Company”), and certain lenders under that certain Loan and Security Agreement, dated as of December 21, 2015 (the “Loan Agreement”), among the Company and the financial institutions and individuals listed on Annex A thereto, who execute this Amendment (the “Lenders”).

FOURTH AMENDMENT TO LEASE
Lease Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

THIS FOURTH AMENDMENT TO LEASE (this "Fourth Amendment") is made as of February 23, 2016, by and between ARE-SEATTLE NO. 10, LLC, a Delaware limited liability company ("Landlord"), and PHASERX INC., a Delaware corporation ("Tenant").

AMENDMENT NO. 2 TO CONSULTING AGREEMENT
Consulting Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

This Amendment No. 2 to Consulting Agreement (this “Amendment”), dated February 10, 2016, is entered into between PhaseRx, Inc., a Delaware corporation having a place of business at 410 West Harrison Street, Seattle, WA 98119 (the “Company”) and Paul H. Johnson, Ph.D., having a place of business at 12020 211th Place SE, Snohomish, Washington 98296 (the “Consultant”).

THIRD AMENDMENT TO LEASE
Lease • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

THIS THIRD AMENDMENT TO LEASE (this "Third Amendment") is made as of _______October 1________, 2014 by and between ARE-SEATTLE NO. 10, LLC, a Delaware limited liability company ("Landlord"), and PHASERX INC., a Delaware corporation ("Tenant").

FIFTH AMENDMENT TO LEASE
Lease Agreement • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

THIS FIFTH AMENDMENT TO LEASE (this "Fifth Amendment") is made as of ______September 8_______, 2015 by and between ARE-SEATTLE NO. 10, LLC, a Delaware limited liability company ("Landlord"), and PHASERX INC., a Delaware corporation ("Tenant").

FOURTH AMENDMENT TO LEASE
Lease • April 18th, 2016 • Phaserx, Inc. • Pharmaceutical preparations

THIS FOURTH AMENDMENT TO LEASE (this "Fourth Amendment") is made as of May 21, 2015 by and between ARE-SEATTLE NO. 10, LLC, a Delaware limited liability company ("Landlord"), and PHASERX INC., a Delaware corporation ("Tenant").

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