0000875320-16-000067 Sample Contracts

EMPLOYMENT AGREEMENT
Employment Agreement • February 16th, 2016 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts

This Employment Agreement (this “Agreement”) is made and entered into as of this 12th day of December, 2014, by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the “Company”), and David Altshuler, M.D., Ph.D. (the “Executive”).

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December 10, 2014
Vertex Pharmaceuticals Inc / Ma • February 16th, 2016 • Pharmaceutical preparations • Massachusetts
STRATEGIC COLLABORATION, OPTION AND LICENSE AGREEMENT
Collaboration, Option and License Agreement • February 16th, 2016 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts

This STRATEGIC COLLABORATION, OPTION AND LICENSE AGREEMENT (this “Agreement”) is entered into as of October 26, 2015 (the “Effective Date”) by and between, on the one hand, VERTEX PHARMACEUTICALS INCORPORATED, a corporation organized and existing under the laws of The Commonwealth of Massachusetts (“Vertex Parent”), and VERTEX PHARMACEUTICALS (EUROPE) LIMITED, a private limited liability company organized under the laws of England and Wales (“Vertex UK” and, together with Vertex Parent, “Vertex”) and, on the other hand, CRISPR THERAPEUTICS AG, a corporation organized under the laws of Switzerland (“CRISPR AG”), CRISPR THERAPEUTICS, INC., a corporation organized under the laws of the state of Delaware (“CRISPR Inc.”), CRISPR THERAPEUTICS LIMITED, a corporation organized under the laws of England and Wales (“CRISPR UK”) and TRACR HEMATOLOGY LTD, a UK limited company (“Tracr” and together with CRISPR AG, CRISPR Inc. and CRISPR UK “CRISPR”). Vertex and CRISPR each may be referred to herein

VERTEX PHARMACEUTICALS INCORPORATED Restricted Stock Unit Award
Restricted Stock Unit Award • February 16th, 2016 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations

This Agreement sets forth the terms and conditions of a Restricted Stock Unit Award granted pursuant to the provisions of the 2013 Stock and Option Plan (as it may be amended or restated, the “Plan”) of Vertex Pharmaceuticals Incorporated (the “Company”) to the Participant whose name appears below, of a contingent entitlement of the Participant to receive the number of Shares of Common Stock of the Company set forth below, pursuant to the provisions of the Plan and on the following express terms and conditions. Capitalized terms not otherwise defined herein shall have the same meanings as set forth in the Plan, and any Restricted Stock Units evidenced hereby are granted subject to the terms of the Plan.

LEASE AGREEMENT
Lease Agreement • February 16th, 2016 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations

THIS LEASE AGREEMENT (this “Lease”) is made this 2nd day of December, 2015, between ARE-SD REGION NO. 23, LLC, a Delaware limited liability company (“Landlord”), and VERTEX PHARMACEUTICALS INCORPORATED, a Massachusetts corporation (“Tenant”).

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