AGREEMENT AND PLAN OF MERGERAgreement and Plan of Merger • April 30th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Delaware
EXHIBIT 10.14Lease • March 26th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
Exhibit 4.4 SECOND AMENDMENT TO RIGHTS AGREEMENT ------------------------------------ SECOND AMENDMENT TO RIGHTS AGREEMENT (the "Second Amendment") dated as of June 30, 2001, to the Rights Agreement (the "Rights Agreement") dated as of July 1, 1991,...Rights Agreement • August 14th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EXHIBIT 10.28Credit Agreement • March 3rd, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EXHIBIT 2.2 ASSET PURCHASE AGREEMENTAsset Purchase Agreement • March 31st, 2003 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • California
EXHIBIT 4.2 RESALE REGISTRATRION RIGHTS AGREEMENT amongRegistration Rights Agreement • November 13th, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
EXHIBIT 10.29 EMPLOYMENT AGREEMENT AGREEMENT, made and entered into as of the 26th day of October, 2001 by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the "Company"), and Ian...Employment Agreement • April 1st, 2002 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
INDENTURE BETWEENIndenture • May 15th, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
Exhibit 99.5 QUORUM SCIENCES, INC. NONQUALIFIED STOCK OPTION AGREEMENT THIS AGREEMENT dated as of September 1, 1999 (the "Date of Grant") by and between QUORUM SCIENCES, INC., a Delaware corporation, 129-8 West Patrick Street, Frederick, Maryland...Nonqualified Stock Option Agreement • July 23rd, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Delaware
CREDIT AGREEMENT Dated as of October 13, 2016 amongCredit Agreement • February 23rd, 2017 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
This CREDIT AGREEMENT is entered into as of October 13, 2016, among VERTEX PHARMACEUTICALS INCORPORATED, a Massachusetts corporation (the “Borrower”), the Subsidiaries of the Borrower as are or may from time to time become parties to this Agreement as Subsidiary Guarantors (defined herein), the Lenders (defined herein), and BANK OF AMERICA, N.A., as Administrative Agent, Swingline Lender and an L/C Issuer.
Exhibit 10.27 EMPLOYMENT AGREEMENT This Employment Agreement (herein referred to as "AGREEMENT") is made and entered into as of this 29th day of April 2001, by and among Aurora Biosciences Corporation (the "COMPANY"), and Harry Stylli ("EXECUTIVE")....Employment Agreement • May 23rd, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • California
1 EXHIBIT 4.3 FORM OFRights Agreement • February 25th, 1997 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
UNDERWRITING AGREEMENT ----------------------Underwriting Agreement • February 25th, 1997 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
Exhibit 10.35 CONFIDENTIAL TREATMENT FIRST REVISED AND RESTATED RESEARCH AND EARLY DEVELOPMENT AGREEMENTConfidential Treatment • September 8th, 2004 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
VERTEX PHARMACEUTICALS INCORPORATED INDENTURE DEBT SECURITIESVertex Pharmaceuticals Inc / Ma • May 3rd, 2016 • Pharmaceutical preparations • New York
INDENTURE dated as of , 20 , among VERTEX PHARMACEUTICALS INCORPORATED, a Massachusetts corporation (the “Company”), and , as trustee (the “Trustee”).
Exhibit 10.32 Form of Change of Control AgreementVertex Pharmaceuticals Inc / Ma • March 31st, 2003 • Pharmaceutical preparations • Massachusetts
EXHIBIT 4.1 INDENTURE BETWEENIndenture • November 13th, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
Exhibit 10.1 Vertex Pharmaceuticals Incorporated has omitted from this Exhibit 10.1 portions of the Agreement for which the Company has requested confidential treatment from the Securities and Exchange Commission. The portions of this Exhibit for...Research Agreement • November 13th, 1998 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EXHIBIT 10.2Vertex Pharmaceuticals Inc / Ma • November 15th, 1999 • Pharmaceutical preparations
EXHIBIT 10.1Research and Development Agreement • November 12th, 1997 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
Second Amendment to LeaseVertex Pharmaceuticals Inc / Ma • March 28th, 1997 • Pharmaceutical preparations
SUBORDINATED INDENTURE VERTEX PHARMACEUTICALS INCORPORATED, ISSUER AND U.S. BANK NATIONAL ASSOCIATION, TRUSTEE INDENTURE Dated as of September 28, 2010 Subordinated Debt SecuritiesVertex Pharmaceuticals Inc / Ma • September 29th, 2010 • Pharmaceutical preparations • New York
INDENTURE, dated as of September 28, 2010, between VERTEX PHARMACEUTICALS INCORPORATED, a corporation duly organized and existing under the laws of the Commonwealth of Massachusetts, having its principal office at 130 Waverly Street, Cambridge, Massachusetts 02139 (the “Company”), and U.S. BANK NATIONAL ASSOCIATION, as trustee (the “Trustee”):
EXHIBIT 10.16Disturbance and Attornment Agreement • March 26th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EXHIBIT 1 NOTICE OF EXERCISEStock Option Agreement • July 23rd, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
EXHIBIT 4.2 RESALE REGISTRATION RIGHTS AGREEMENTResale Registration Rights Agreement • May 15th, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
Exhibit 10.9Employment Agreement • March 26th, 2001 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • England and Wales
INDENTURE BETWEEN VERTEX PHARMACEUTICALS INCORPORATED, AS ISSUER AND U.S. BANK NATIONAL ASSOCIATION, AS TRUSTEE 4.75% CONVERTIBLE SENIOR SUBORDINATED NOTES DUE 2013 DATED AS OF FEBRUARY 19, 2008Indenture • February 25th, 2008 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
INDENTURE, dated as of February 19, 2008, between VERTEX PHARMACEUTICALS INCORPORATED, a corporation duly organized and existing under the laws of the Commonwealth of Massachusetts, having its principal office at 130 Waverly Street, Cambridge, Massachusetts 02139 (the “Company”), and U.S. BANK NATIONAL ASSOCIATION, as trustee (the “Trustee”), having its principal corporate trust office at One Federal Street, Boston, Massachusetts 02110.
Exhibit 10.26 AURORA BIOSCIENCES CORPORATION 11010 Torreyana Road San Diego, California 92121 Stuart J.M. Collinson, Ph.D. 4810 Tarantella Lane San Diego, CA 92130 Re: Employment Terms Dear Stuart: This letter ("Agreement") sets forth the agreement...Vertex Pharmaceuticals Inc / Ma • May 23rd, 2001 • Pharmaceutical preparations • California
CREDIT AGREEMENT Dated as of January 7, 2011 among VERTEX PHARMACEUTICALS INCORPORATED, as the Borrower, BANK OF AMERICA, N.A., as Administrative Agent, and The Other Lenders Party HeretoCredit Agreement • May 6th, 2011 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
This CREDIT AGREEMENT (“Agreement”) is entered into as of January 7, 2011, among VERTEX PHARMACEUTICALS INCORPORATED, a Massachusetts corporation (the “Borrower”), each lender from time to time party hereto (collectively, the “Lenders” and individually, a “Lender”), and BANK OF AMERICA, N.A., as Administrative Agent.
EMPLOYMENT AGREEMENTEmployment Agreement • May 1st, 2019 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
This Employment Agreement (this “Agreement”) is made and entered into as of this 28th day of March, 2019, by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the “Company”), and Charles F. Wagner, Jr. (the “Executive”).
INDENTURE BETWEEN VERTEX PHARMACEUTICALS INCORPORATED, AS ISSUER AND US BANK NATIONAL ASSOCIATION, AS TRUSTEE 5¾% CONVERTIBLE SENIOR SUBORDINATED NOTES DUE 2011 DATED AS OF SEPTEMBER 17, 2004Indenture • September 17th, 2004 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
INDENTURE, dated as of September 17, 2004, between VERTEX PHARMACEUTICALS INCORPORATED, a corporation duly organized and existing under the laws of the Commonwealth of Massachusetts, having its principal office at 130 Waverly Street, Cambridge, Massachusetts 02139 (the “Company”), and US BANK NATIONAL ASSOCIATION, as trustee (the “Trustee”), having its principal corporate trust office at One Federal Street, Boston, Massachusetts 02110.
EMPLOYMENT AGREEMENTEmployment Agreement • May 12th, 2008 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
AGREEMENT, made and entered into as of February 11, 2008 by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the "Company"), and John Alam (the "Executive").
EXHIBIT 10.27 (WITH CERTAIN CONFIDENTIAL INFORMATION DELETED AND MARKED WITH BRACKETED ASTERIKS)Collaboration and Option Agreement • March 3rd, 2000 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
NON COMPETITION AGREEMENTNon Competition Agreement • March 31st, 2003 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
May 18, 2012Vertex Pharmaceuticals Inc / Ma • February 13th, 2020 • Pharmaceutical preparations • Massachusetts
