Sensitivity. At the highest level of confidence (level 5, lesion definitely present), sensitivity for correctly localized malignant lesions on digital chest radiography varied from 18% (95% CI: 10%, 32%) to 49% (95% CI: 36%, 63%) at a specificity of 100% (95% CI: 94%, 100%) to 92% (95% CI: 82%, 97%). The false-positive rates in the control group at this level of con- fidence ranged from 0% (0 of 72) to 13% (9 of 72) for observers D and C, respectively. When lesions rated as probably present (level 4) were taken into ac- count, sensitivity increased to 36% (95% CI: 24%, 50%) for observer D and 73% (59%, 84%) for observer A, with specificities of 99% (95% CI: 50%, 76%) and 82% (95% CI: 71%, 90%), respectively (Table 3). Most lesions that had been rated as definitely present at chest radiography
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