Refinement. Areas needing further
Refinement. Refine the way experiments are carried out, and animals are housed, managed and handled, to reduce negative impacts and increase positive welfare. For example, appropriate pain relief, enhanced environmental enrichment and positive reinforcement behavioural training to accomplish tasks. This means that animals can only be used when there are no reliable or suitable alternatives, the number of animals used is minimised and any potential harm to animals must be minimised and weighed against the potential benefit to humans or other animals. Scientific advances have changed the use of animals in research. Recent developments let researchers reduce the number of animals used and have helped researchers refine their methods to minimise or eliminate pain and distress. Opportunities for re-homing animals are also available, where appropriate. The Three Rs are also promoted, through yearly awards at various institutions and a biennial implementation award from the government, for research that advances at least one of the three principles. The long-term goal is the replacement of animals used in research, as science, technology and law permits. The status of the Openness Agreement This Agreement has been developed proactively and is supported by its signatories in addition to their legal and regulatory obligations within New Zealand. Signatories are expected to proactively work towards fulfilling the five Commitments. If an organisation is unable to make any progress, it will be asked to reconsider its position as a signatory to the Agreement. All signatories agree to take steps to be more open about their use of animals in research and teaching in line with the five Commitments. Exactly how these Commitments are fulfilled will differ between organisations depending upon their operation and purpose, their capacity and their different legal obligations. All images are licensed under a Creative Commons 4.0 International license. Understanding Animal Research – xxxxx://xxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx.xx/ Signatories ANZCCART is a member organisation of Royal Society Te Apārangi | xxxxxxxx@xxxxxxxxxxxx.xxx.xx xxx.xxxxxxxx.xxx.xx 00 Xxxxxxxx Xxxxxx, Thorndon, Wellington 6011 PO Box 598, Wellington 6140, New Zealand T +00 0 000 0000 | xxxxxxxxxxxx.xxx.xx
Refinement a. Centrifuge/Manual Separations
Refinement. An important technique that speeds up the search is called refinement. The formal idea for the graph automorphism problem is that for each pair of elements in a single cell of ordered partition π, they must be neighbors to the same number of elements in every cell of π. Otherwise, they need to be split into different cells, since there is no way they can map to the same set of nodes. Refinement can be done on the top and bottom separately and if the resulting OPP is non-isomorphic, we can stop the recursive search. A related complication is that the adjacency frequencies should be isomorphic for every pair of top and bottom cells. As such, it is often useful to refine the top and bottom simultaneously[33]. Refinement is essential for efficient algorithms, but it is a time-consuming pro- cess and is typically the bottleneck of automorphism algorithms. Models can vastly outnumber literals, which means much unnecessary time can be spent on performing refinement on the clausal nodes. Since representing clausal symme- tries is unnecessary, given that they are side-effects of the variable symmetries, we choose to compute symmetries using the variable representation without trans- forming it first into a graph. A key difference between JAUNTY and saucy is when comparing the frequen- cies of literals x and y, the frequencies of the literals ¬x and ¬y also have to be equal. Two literals as considered ”neighbors” if they exist in the same clause. If they coexist in more than one clause, this frequency is used during refinement. The information can be easily stored in a 2|V | × 2|V | matrix, so the only time we need to work with the formula is when verifying that a generated permutation is indeed a symmetry – an infrequent occurrence. Since we will also need to find symmetries on typical CNF instances with many variables, that matrix can be much too large. So there is also a sparse version of refinement that works more nicely on typical CNF instances. Through effective use of data structures we are able to compute refinements on very large problems very quickly.
Refinement. Project full title: " Financing systems’ effects on the Quality of Mental health care in Europe " Grant agreement no: 261459 Date of preparation of Xxxxx X (latest version): 2010-07-02 Date of last change: 2010-06-30 Date of approval of Annex I by Commission: Table of Contents Part A
Refinement. Infinitive-selecting verbs Some infinitive-selecting verbs object-agree with object of infinitive complement (xcomp): (38) a. Meg-pr´ob´al-ok ritk-´abb-an vesz´ıteni el dolg-ok-at. perf-try-1sg.indef rare-more-ly lose.inf away thing-pl-acc ‘I’m trying to lose things more rarely.’
Refinement. Teeth may not move as anticipated. There are many potential reasons for teeth not moving according to plan. This may be due to incomplete compliance, where the aligners are not worn as directed. Some teeth may be too short and insufficient tooth may be available for aligners to engage. Some teeth may be ankylosed, which is fused to the jawbone and unable to move. Patients may require additional impressions, or intra-oral scans, and/or refinement aligners after the initial series of aligners. This may be necessary to optimize the outcome. There may be additional expenses associated with refinement aligners. Retainers: at the conclusion of active orthodontic treatment, it will be necessary to maintain the teeth and prevent them from shifting. Various options for retention are discussed by your doctor, which include removable retainers or fixed retainers. x
Refinement. Notwithstanding the warranties provided elsewhere herein, Buyer acknowledges that Licensed Software may be product, aircraft, or sensor specific and, as such, may require reasonable adjustment or refinement to suit Buyer’s specific requirements. Subject to the receipt of adequate written notice and reasonable aid from Xxxxx, Vindicator will make reasonable, commercial efforts to accomplish reasonable adjustments or refinements for up to 90 calendar days after initial delivery of the Licensed Software.
Refinement. A preliminary design will be developed using the Basis of Design proposed by SDE, reviewed by City Staff in several drafts prior to this signing, and in substantially final form as Exhibit A attached hereto. The parties will use their good faith reasonable efforts to finalize this BOD within 7 days of signing this Development Agreement, and to finalize a preliminary design based on the approved BOD within 14 days thereafter. It is understood that the schedule reflects that land use permit filings may be made prior to the finalization of preliminary design, since these focus on exterior details that may be agreed upon before the entire preliminary design is completed. FINAL PARKING COUNT The goal of the parties is to arrive at the minimum number of parking spaces necessary to balance the needs of the City and developer, taking into account the following: • Code and practical access concerns raised by proposed development on the North Unit • Code and practical access concerns raised by proposed development on the South Unit • Final number of parking spaces required to service the needs of the North and South Unit • City’s determination of final financial feasibility (i.e. a count that permits a feasible revenue stream for its needs) WINOOSKI FALLS EAST DEVELOPMENT AGREEMENT EXHIBIT B: THE PLANS [ATTACHED BASIS OF DESIGN AT EXECUTION; TO FOLLOW UP WITH PRELIMINARY DESIGN AND FINAL PLANS] BASIS OF DESIGN ot 7D Winooski Falls Parking Structure January 28, 2020 Winooski, Vermont Owner: City of Winooski Engineer-of-Record: Simon Design Engineering, LLC (SDE) Client: Nedde Real Estate Construction Manager: DEW Construction GENERAL
