Rational Sample Clauses

The 'Rational' clause defines the underlying reasoning or justification for including certain terms or provisions within a contract. Typically, this clause outlines the business, legal, or practical motivations that led the parties to agree on specific obligations or limitations. For example, it may explain why a particular liability cap is set or why certain performance standards are required. Its core function is to provide context and clarity, helping to interpret the contract's intent and resolve ambiguities by referencing the parties' original rationale.
Rational a) All properties are susceptible to spills whether it is a result of operations or by customers. Insufficient response, inadequate containment materials and improper spill cleanup methods will result in pollutants in our waterways. Once the pollutants reach our storm drain system, or even the detention pond, they are difficult and expensive to remove.
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Rational. The premium (Prospective, Randomized Investigation to Evaluate Incidence of Headache Reduction in Subjects With Migraine and PFO Using the AMPLATZER PFO Occluder to Medical Management) study hypothesis was based on the possible significant reduction in the frequency of migraine attacks with and without aura after percutaneous correction of PFO and broad dx-sin shunt in patients symptomatic for migraine from 6 to 14 days/month and not responsive to drug therapies. The primary endpoint of the studywas to reduce the frequency of migraine attacks (with or without aura) by at least 50%; the proportion of patients with headache reduction was superimposable in the PFO correction group (38.5%) and in that addressed to medical therapy (32%), p=0.32. With regard to secondary endpoints, there was a significant reduction in the number of migraine days/month after CORRECTION of PFO compared to the control group (: –3.4 ±4.4 days versus –2.0 ±5.0 days (p = 0.025). No difference was observed in the percentage of patients who achieved a 75% reduction > migraine attacks while a very significant difference was observed with regard to subjects who experienced a complete regression of migraine episodes: 8.5% (10/117) in the PFO correction group vs 1.0% (1/103) in the medical therapy group (p=0.01). Among these patient responders, 6 were symptomatic for migraine with aura while the other 4 were migraines with isolated episodes of aura. It could be speculated that the etiological mechanism of headache in patients not subjected to PFO closure could be the activation of platelets inside the tunnel, the overlap between septum primum and secundum, of the patent foramen ovale. This segment, which may be characterized by a potential flow turbulence between the two septa, could lead to platelet activation, especially in the presence of SIA aneurysm. In a small group of patients with migraine, resistance to aspirin has been documented in 24% of subjects, suggesting platelet hyper-reactivity. Clopidogrel and aspirin are more effective than aspirin alone in reducing headache, exacerbated after percutaneous correction of PFO in the first follow-up period24 to demonstrate that platelet microaggregates may be responsible for post-closure migraine of PFO and may play a central role in the genesis of headache. In women and patients with stable coronary artery disease, in antiplatelet therapy with aspirin, high platelet reactivity (HAPR) or resistance to aspirin has been described and is assoc...
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Rational 
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Related to Rational

  • Mileage Measurement Where required, the mileage measurement for LIS rate elements is determined in the same manner as the mileage measurement for V&H methodology as outlined in NECA Tariff No. 4.

  • Usage Measurement Usage measurement for calls shall begin when answer supervision or equivalent Signaling System 7 (SS7) message is received from the terminating office and shall end at the time of call disconnect by the calling or called subscriber, whichever occurs first.

  • Benchmarking The Parties shall comply with the provisions of Framework Schedule 12 (Continuous Improvement and Benchmarking) in relation to the benchmarking of any or all of the Goods and/or Services.

  • Shift Rotation Routine shift rotation is not an approach to staffing endorsed by the Employer. Except for emergency situations where it may be necessary to provide safe patient care, shift rotation will not be utilized without mutual consent. If such an occasion should ever occur, volunteers will be sought first. If no one volunteers, the Employer will rotate shifts on an inverse seniority basis until the staff vacancies are filled.

  • New Classification Should a new position or new classification be created within the Bargaining Unit during the term of this Agreement, the Employer and the Union will decide the rate of pay. Nothing herein prevents the Employer from filling such positions and having Nurses working in such positions during such negotiations. The salary when determined will be retroactive to the date on which the successful candidate commenced work in that classification.