Common use of Electronic Copy Clause in Contracts

Electronic Copy. The parties to this document agree that a copy of the original signature (including an electronic copy) may be used for any and all purposes for which the original signature may have been used. The parties further waive any right to challenge the admissibility or authenticity of this document in a court of law based solely on the absence of an original signature. Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. The parties execute this Agreement in duplicate originals by their duly authorized officers or representatives. THE BOARD OF TRUSTEES OF THE XXXXXX XXXXXXXXX JUNIOR UNIVERSITY Signature /s/ Xxxxxxxxx Xx Name Xxxxxxxxx Xx Title Director, Office of Technology Licensing Date January 24, 2012 RUGA CORPORATION Signature /s/ Xxx Xxxxxxxxxx Name Xxx Xxxxxxxxxx Title President and CEO Date January 24, 2012 Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. APPENDIX A [*****] Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. APPENDIXB SAMPLE REPORTING FORM Stanford Docket No. S This report is provided pursuant to the license agreement between Stanford University and (RUGA Name) License Agreement Effective Date: Name(s) of Licensed Product(s): Report Covering Period Yearly Maintenance Fee $ Number of Sublicenses Executed Gross Sales $ Net Sales $ Royalty Calculation Royalty Subtotal $ Credit $ Royalty Due $ Comments: Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. CLIENT AND BILLING AGREEMENT The Board of Trustees of the Xxxxxx Xxxxxxxx Junior University (“STANFORD”); and , a Corporation of the State of, ,with a principal place of business at , (“RUGA”); have agreed to use the law firm of (“FIRM”) to prepare, file and prosecute the pending patent applications listed in Exhibit A attached hereto and maintain the patents that issue thereon (“Patents”).

Electronic Copy. The parties to this document agree that a copy of the original signature (including an electronic copy) may be used for any and all purposes for which the original signature may have been used. The parties further waive any right to challenge the admissibility or authenticity of this document in a court of law based solely on the absence of an original signature. Portions herein identified by [*****] have * Certain information in this agreement has been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been and filed separately with the Securities and Exchange Commission. [***] indicates that text has been omitted and is the subject of a confidential treatment request. The parties execute this Agreement in duplicate originals by their duly authorized officers or representatives. THE BOARD OF TRUSTEES OF THE XXXXXX XXXXXXXXX XXXXXXXX JUNIOR UNIVERSITY Signature Signature: /s/ Xxxxxxxxx Xx Name Xxxxxxxxx Xx Title Xxxxxxx Xxxxx Name: Xxxxxxx Xxxxx Title: Acting Director, Office of Technology Licensing Date January Date: March 24, 2012 RUGA CORPORATION Signature 2015 Alexo Therapeutics International Signature: /s/ Xxx Xxxxxxxxxx Name Xxx Xxxxxxxxxx Title President and CEO Date January Xxxxx Xxxxxxx Name: Xxxxx Xxxxxxx Title: Chair, Board of Directors Date: March 24, 2012 Portions herein identified by [2015 *****] have * Certain information in this agreement has been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been and filed separately with the Securities and Exchange Commission. APPENDIX A [*****] Portions herein identified by indicates that text has been omitted and is the subject of a confidential treatment request. Appendix A - Milestones [***] **] have * Certain information in this agreement has been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been and filed separately with the Securities and Exchange Commission. APPENDIXB SAMPLE REPORTING FORM [***] indicates that text has been omitted and is the subject of a confidential treatment request. Xxxxxxxx X — Sample Reporting Form Stanford Docket No. S This report is provided pursuant to the license agreement between Stanford University and (RUGA Alexo Name) License Agreement Effective Date: Name(s) of Licensed Product(s): Products being reported: Report Covering Period Yearly Maintenance Fee $ Number of Sublicenses Executed Gross Sales Revenue U.S. Gross Revenue Non-U.S. Gross Revenue $ $ Net Sales U.S. Gross Revenue Non-U.S. Gross Revenue $ $ Royalty Calculation Royalty Subtotal $ Credit $ Royalty Due $ Comments: Portions herein identified by [*****] have * Certain information in this agreement has been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been and filed separately with the Securities and Exchange Commission. CLIENT AND BILLING AGREEMENT [***] indicates that text has been omitted and is the subject of a confidential treatment request. Appendix C — Client and Billing Agreement The Board of Trustees of the Xxxxxx Xxxxxxxx Junior University (“STANFORD”); and Alexo Therapeutics International a Cayman Islands exempted company, a Corporation of the State of, ,with a principal place of business mailing address at [951 Xxxxxxx Xxxx, Xxxxx 000, Xxxxx Xxx Xxxxxxxxx, XX 00000], (“RUGAALEXO”); have agreed to use the law firm of (“FIRM”) to prepare, file and prosecute the pending patent applications listed in Exhibit A attached hereto and maintain the patents that issue thereon (“Patents”).

Electronic Copy. The parties to this document agree that a copy of the original signature (including an electronic copy) may be used for any and all purposes for which the original signature may have been used. The parties further waive any right to challenge the admissibility or authenticity of this document in a court of law based solely on the absence of an original signature. Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. The parties execute this Agreement in duplicate originals by their duly authorized officers or representatives. THE BOARD OF TRUSTEES OF THE XXXXXX XXXXXXXXX XXXXXXXX JUNIOR UNIVERSITY Signature /s/ Xxxx Xxxxxxxxx Xx Name Xxxx Xxxxxxxxx Xx Title DirectorActing Director Date October 27, Office of Technology Licensing Date January 242015 EICCOSE, 2012 RUGA CORPORATION LLC. Signature /s/ Xxx Xxxxxxxxxx Xxxxx Xxxx Name Xxx Xxxxxxxxxx Xxxxx Xxxx Title President and CEO Date January 24[ * ] = Certain confidential information contained in this document, 2012 Portions herein identified marked by [*****] have been omitted brackets, is filed with the Securities and Exchange Commission pursuant to a request for confidential treatment under Rule 406 24b-2 of the Securities Exchange Act of 19331934, as amended. APPENDIX A complete copy of EICCOSE DEVELOPMENT AND REGULATORY PLAN FOR LTB4 INHIBITORS IN LYMPHEDEMA [ * ] [ * ] = Certain confidential information contained in this document has been document, marked by brackets, is filed separately with the Securities and Exchange Commission. APPENDIX A [*****] Portions herein identified by [*****] have been omitted Commission pursuant to a request for confidential treatment under Rule 406 24b-2 of the Securities Exchange Act of 19331934, as amended. A complete copy XXXXXXXX X – Sample Reporting Form STANFORD DOCKET NO. S14-323 THIS REPORT IS PROVIDED PURSUANT TO THE LICENSE AGREEMENT BETWEEN STANFORD UNIVERSITY AND (EICCOSE, LLC) LICENSE AGREEMENT EFFECTIVE DATE: Name(s) of Licensed Products being reported: REPORT COVERING PERIOD YEARLY MAINTENANCE FEE $ NUMBER OF SUBLICENSES EXECUTED NET SALES $ ROYALTY CALCULATION ROYALTY SUBTOTAL $ CREDIT $ ROYALTY DUE $ COMMENTS: [ * ] = Certain confidential information contained in this document has been document, marked by brackets, is filed separately with the Securities and Exchange Commission. APPENDIXB SAMPLE REPORTING FORM Stanford Docket No. S This report is provided Commission pursuant to the license agreement between Stanford University and (RUGA Name) License Agreement Effective Date: Name(s) of Licensed Product(s): Report Covering Period Yearly Maintenance Fee $ Number of Sublicenses Executed Gross Sales $ Net Sales $ Royalty Calculation Royalty Subtotal $ Credit $ Royalty Due $ Comments: Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 406 24b-2 of the Securities Exchange Act of 19331934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. CLIENT AND BILLING AGREEMENT The Board of Trustees of the Xxxxxx Xxxxxxxx Junior University (“STANFORD”); and , a Corporation of the State of, ,with a principal place of business at , (“RUGA”); have agreed to use the law firm of (“FIRM”) to prepare, file and prosecute the pending patent applications listed in Exhibit A attached hereto and maintain the patents that issue thereon (“Patents”).

Electronic Copy. The parties to this document agree that a copy of the original signature (including an electronic copy) may be used for any and all purposes for which the original signature may have been used. The parties further waive any right to challenge the admissibility or authenticity of this document in a court of law based solely on the absence of an original signature. Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. The parties execute this Agreement in duplicate originals by their duly authorized officers or representatives. THE BOARD OF TRUSTEES OF THE XXXXXX XXXXXXXXX XXXXXXXX JUNIOR UNIVERSITY Signature Signature: /s/ Xxxxxxxxx Xx Name Name: Xxxxxxxxx Xx Title DirectorTitle: Executive Director Date: November 19, Office of Technology Licensing Date January 242015 FORTY SEVEN, 2012 RUGA CORPORATION INC. Signature /s/ Xxx Xxxxxxxxxx Name Xxx Xxxxxxxxxx Title President and Xxxxxxxx XxxXxxxxx Name: Xxxxxxxx XxxXxxxxx Title: CEO Date January 24Date: November 19, 2012 Portions herein identified by 2015 [*****] have = Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. Appendix A complete copy of - Milestones [*] [*] = Certain confidential information contained in this document document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission. APPENDIX A [*****] Portions herein identified by [*****] have been omitted Commission pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. APPENDIXB SAMPLE REPORTING FORM Appendix B – Sample Reporting Form Stanford Docket No. S S- This report is provided pursuant to the license agreement between Stanford University and (RUGA Company Name) License Agreement Effective Date: Name(s) of Licensed Product(s): Products being reported: Report Covering Period Yearly Maintenance Fee $ Number of Sublicenses Executed Gross Sales Revenue U.S. Gross Revenue Non-U.S. Gross Revenue $ $ Net Sales U.S. Net Sales Non-U.S. Net Sales $ $ Royalty Calculation Royalty Subtotal $ Credit $ Royalty Due $ Comments: Portions herein identified by [*****] have = Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities Appendix C – Client and Exchange Commission. CLIENT AND BILLING AGREEMENT Billing Agreement The Board of Trustees of the Xxxxxx Xxxxxxxx Junior University (“STANFORD”); and , a Corporation of the State ofof , ,with a principal place of business at , (“RUGACOMPANY”); have agreed to use the law firm of (“FIRM”) to prepare, file and prosecute the pending patent applications listed in Exhibit A attached hereto and maintain the patents that issue thereon (“Patents”).

Electronic Copy. The parties Parties to this document agree that a copy of the original signature (including an electronic copy) may be used for any and all purposes for which the original signature may have been used. The parties Parties further waive any right to challenge the admissibility or authenticity of this document in a court of law based solely on the absence of an original signature. [Signature Page Follows] Portions herein identified of the exhibit, indicated by the xxxx “[*****] ],” were omitted and have been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange CommissionCommission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended. CONFIDENTIAL TREATMENT REQUESTED The parties Parties execute this Agreement in duplicate originals by their duly authorized officers or representatives. THE BOARD OF TRUSTEES OF THE XXXXXX XXXXXXXXX JUNIOR UNIVERSITY PIERIS PHARMACEUTICALS, INC. Signature /s/ Xxxxxxxxx Xx Name Xxxxxxxxx Xx Title Director, Office of Technology Licensing Date January 24, 2012 RUGA CORPORATION Signature /s/ Xxx Xxxxxxxxxx Name Xxx Xxxxxxxxxx Xxxxxxx Xxxxx Title President and CEO Date January 24PIERIS PHARMACEUTICALS GMBH Signature Name Xxxxxxx Xxxxx Title Managing Director Date ASKA PHARMACEUTICAL CO., 2012 LTD. Signature Name Xxxxxxx Xxxxxxxxx, Ph.D. Title President and Representative Director Date Portions herein identified of the exhibit, indicated by the xxxx “[*****] ],” were omitted and have been omitted pursuant to a request for confidential treatment under Rule 406 of the Securities Exchange Act of 1933, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission. APPENDIX A [*****] Portions herein identified by [*****] have been omitted Commission pursuant to a request for the Registrant’s application requesting confidential treatment under pursuant to Rule 406 24b-2 of the Securities Exchange Act of 19331934, as amended. CONFIDENTIAL TREATMENT REQUESTED EXHIBIT A complete copy Patent Rights within the Licensed Platform IP [***] Portions of this document has the exhibit, indicated by the xxxx “[***],” were omitted and have been filed separately with the Securities and Exchange Commission. APPENDIXB SAMPLE REPORTING FORM Stanford Docket No. S This report is provided Commission pursuant to the license agreement between Stanford University and (RUGA Name) License Agreement Effective Date: Name(s) of Licensed Product(s): Report Covering Period Yearly Maintenance Fee $ Number of Sublicenses Executed Gross Sales $ Net Sales $ Royalty Calculation Royalty Subtotal $ Credit $ Royalty Due $ Comments: Portions herein identified by [*****] have been omitted Registrant’s application requesting confidential treatment pursuant to a request for confidential treatment under Rule 406 24b-2 of the Securities Exchange Act of 19331934, as amended. A complete copy CONFIDENTIAL TREATMENT REQUESTED EXHIBIT B Patent Rights within the Licensed Product IP [***] Portions of this document has the exhibit, indicated by the xxxx “[***],” were omitted and have been filed separately with the Securities and Exchange Commission. CLIENT AND BILLING AGREEMENT The Board of Trustees Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of the Xxxxxx Xxxxxxxx Junior University (“STANFORD”); and Securities Exchange Act of 1934, a Corporation as amended. CONFIDENTIAL TREATMENT REQUESTED EXHIBIT C Success Criteria for Phase 2a Study [***] Portions of the State ofexhibit, indicated by the xxxx “[***],” were omitted and have been filed separately with a principal place the Securities and Exchange Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 24b-2 of business at the Securities Exchange Act of 1934, (“RUGA”); have agreed to use as amended. CONFIDENTIAL TREATMENT REQUESTED EXHIBIT D The Definitive Agreements, if executed, will include the law firm following upfront and milestone payments, royalties and other terms in consideration of (“FIRM”) to prepare, file and prosecute the pending patent applications listed in Exhibit A attached hereto and maintain rights granted under the patents that issue thereon (“Patents”).Licensed Product IP: