Common use of Double Stranded Development Milestones Clause in Contracts

Double Stranded Development Milestones. Alnylam, its Affiliates or sublicensees (except Naked Sublicensees) will pay to Isis the following milestone payments for each Alnylam Double Stranded RNA Product within [**] after the first achievement of each of the following events: Milestone Event Milestone Payment Initiation of Phase I Trial US$[**] Initiation of Phase III Trial US$[**] Filing NDA US$[**] Marketing Approval US$[**] Each milestone payment under this Section 7.3(c) will only be due on the [**] Alnylam Double Stranded RNA Product that modulates a particular Gene Target to trigger such milestone payment, whether such milestone is achieved by Alnylam or an Affiliate or sublicensee of Alnylam.

Double Stranded Development Milestones. Alnylam, its Affiliates or sublicensees (except Naked Sublicensees) will pay to Isis the following milestone payments for each Alnylam Double Stranded RNA Product within [***] [***] after the first achievement of each of the following events: Milestone Event Milestone Payment Initiation of Phase I Trial US$[***] Initiation of Phase III Trial US$[***] Filing NDA US$[***] Marketing Approval US$[***] Each milestone payment under this Section 7.3(c) will only be due on the [***] Alnylam Double Stranded RNA Product that modulates a particular Gene Target to trigger such milestone payment, whether such milestone is achieved by Alnylam or an Affiliate or sublicensee of Alnylam.

Double Stranded Development Milestones. Alnylam, its Affiliates or sublicensees (except Naked Sublicensees) will pay to Isis the following milestone payments for each Alnylam Double Stranded RNA Product within [**] *]days after the first achievement of each of the following events: Milestone Event Milestone Payment Initiation of Phase I Trial US$[**] 375,000 Initiation of Phase III Trial US$[**] 750,000 Filing NDA US$[***] Marketing Approval US$[***] Each milestone payment under this Section 7.3(c) will only be due on the [***] Alnylam Double Stranded RNA Product that modulates a particular Gene RNA Target to trigger such milestone payment, whether such milestone is achieved by Alnylam or an Affiliate or sublicensee of Alnylam. Notwithstanding the foregoing, the provisions of this Section 7.3(c) shall not apply to any Agricultural Field Product.

Double Stranded Development Milestones. Alnylam, its Affiliates or sublicensees (except Naked Sublicensees) will pay to Isis the following milestone payments for each Alnylam Double Stranded RNA Product within [***] days after the first achievement of each of the following events: Milestone Event Milestone Payment Initiation of Phase I Trial US$[**] US$ 375,000 Initiation of Phase III Trial US$US$ 750,000 Filing NDA US$ [**] Filing NDA US$[**] Marketing Approval US$US$ [***] Each milestone payment under this Section 7.3(c) will only be due on the [***] Alnylam Double Stranded RNA Product that modulates a particular Gene RNA Target to trigger such milestone payment, whether such milestone is achieved by Alnylam or an Affiliate or sublicensee of Alnylam. Notwithstanding the foregoing, the provisions of this Section 7.3(c) shall not apply to any Agricultural Field Product.