Validated Hit definition

Validated Hit means a Collaboration Hit, Special Collaboration Hit or Non-Field Hit that has met the criteria for validation set forth in the Research Plan. For purposes of this Agreement, (i) the words “include,” “includes” and “including” shall be deemed to be followed by the words “without limitation,” (ii) the word “or” is not exclusive, (iii) the words “herein,” “hereof,” “hereby,” “hereto” and “hereunder” refer to this Agreement as a whole, and (iv) each definition shall be equally applicable to the singular and plural forms of the terms defined. Unless the context otherwise requires, references herein: (A) to Sections and Schedules mean the Sections of and Schedules to this Agreement; (B) to an agreement, instrument or other document means such agreement, instrument or other document as amended, supplemented and modified from time to time to the extent permitted by the provisions thereof and by this Agreement; and (C) to a statute means such statute as amended from time to time and includes any successor legislation thereto and any regulations promulgated thereunder. The Schedules referred to herein shall be construed with and as an integral part of this Agreement to the same extent as if they were set forth verbatim herein.
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Validated Hit means a small molecule that has shown activity against a Target in primary screening as part of the Research Collaboration.
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Validated Hit shall be limited solely to Collaboration Hits identified in a Project Discovery Round that have met the criteria for validation of such type of Collaboration Hit as set forth in the Research Plan.
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Examples of Validated Hit in a sentence

  • The Research Plan may include a general overview and timetable for development and implementation of the Funded Project, details regarding the Evogene Diligence Obligations and the Monsanto Diligence Obligations, schedules for deliverables, test protocols and procedures, thresholds for determination of a Validated Hit, procedures for disclosing and delivering Collaboration Hits, Special Collaboration Hits, and Preferred Modes of Use to Monsanto, and descriptions of other research activities.

  • Each Special Collaboration Hit that undergoes Core Validation or Model Plant Validation shall constitute a Collaboration Hit hereunder, regardless whether such Special Collaboration Hit qualifies as a Validated Hit.

  • Amgen shall pay Anadys a one-time research milestone payment of [...***...] Dollars ($[...***...]) within thirty (30) days after Amgen selects, by written notice to Anadys, the first Validated Hit (regardless of whether such Validated Hit is an Amgen Library Validated Hit or an Anadys Library Validated Hit) for Phase 3.

  • Phytera also agrees to deliver all Extracts on a timely basis and to conduct NPCII on Validated Hit Extracts and all other actions required of it in connection with the Program expeditiously and in a scientifically sound manner.

  • The Bank of Thailand Monetary Policy Committee (MPC) increased its 1-day RP rate by 0.25% in July and another 0.25% in August, in order to reduce inflation risk and attain inflation target after world crude oil prices raised significantly.

  • In the event of Early Termination of this Agreement, pursuant to Section 5.2, the obligations of the Parties to continue to fund NPCII activities that are underway, with respect to specific Validated Hit Extracts at the time notice of Early Termination is received shall survive such termination.

  • Budget estimates shall be furnished by both Phytera and NeuroSearch as soon as practicable following a determination by the Committee to undertake NPCII with respect to one or more Validated Hit Extracts.

  • If so, the Committee shall then designate between [ ]* Extracts that have been determined to possess Requisite Activity as Validated Hit Extracts.

  • The Parties shall jointly own all discoveries, information, technology or inventions made or created jointly by employees, agents or consultants of both Parties during the course of their performance under the Collaboration Program and all intellectual property rights related thereto, without regard, in the case of Validated Hits and Program Products, to whether a Knoll Substance or Tularik Substance was selected as a Validated Hit upon which Program Products may be based.

  • Amgen shall pay Anadys $[...***...] for each such Amgen-SelecTed Validated Hit within thirty (30) days of the foregoing written notice or written notice under Section 3(b) above.


More Definitions of Validated Hit

Validated Hit means an Anadys Library Validated Hit or an Amgen Library Validated Hit.
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Validated Hit means a Library Compound or Research Compound that agonizes or antagonizes a Program Target in confirmatory screening of Hits as part of the Research Program.
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Validated Hit means an Anadys Library Compound or an Aphoenix Library Compound that in a Target Assay yields results that meet the Target Assay Criteria.
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Validated Hit means [***].
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Validated Hit means a Hit that substantially demonstrates:
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Related to Validated Hit

  • Licensed Level means a) when referenced in the context of a Named User, the quantity of Metric for which each individual Named User category and type is licensed -and- b) when referenced in the context of a Package, the quantity of Metric for which each individual Package is licensed; and

  • Research Project means a discrete scientific endeavor to answer a research question or a set of research questions related to medical marijuana and is required for a medical marijuana research license.

  • conformity assessment body means a body that performs conformity assessment activities including calibration, testing, certification and inspection;

  • Approved Project means the Scheme application of the Applicant approved by the CIC.

  • The Contract Price/Project Cost means the price payable to the Vendor under the Contract for the full and proper performance of its contractual obligations.

  • Major project means a project comprising of a series of works, activities or services which is intended, in itself, to accomplish a definite and indivisible task of a precise economic or technical nature, which has clearly identified goals and whose total cost exceeds that which is specified in the Framework Agreement;

  • Development Cost means the total of all costs incurred in the completion of a Development excluding Developer Fee, operating deficit reserves, and total land cost as typically shown in the Development Cost line item on the development cost pro forma.

  • Biomarker means a parameter or characteristic in a patient or Patient Sample, the measurement of which is useful (a) for purposes of selecting appropriate therapies or patient populations or monitoring disease susceptibility, severity or state, or monitoring therapies for such patient and/or (b) for predicting the outcome of a particular treatment of such patient.

  • Total Project Cost means all the funds to complete the effort proposed by the Applicant, including DOE funds (including direct funding of any FFRDC) plus all other funds that will be committed by the Applicant as Cost Sharing.

  • First Indication means the first disease condition for which a particular Licensed Product has been approved by a Regulatory Authority.

  • Project Cost means the costs incurred in connection with the

  • The Works/Project means the works to be executed or done under this contract.

  • The Project Plan means the document to be developed by the Supplier and approved by the Purchaser, pursuant to GCC Clause 19, based on the requirements of the Contract and the Preliminary Project Plan included in the Supplier’s bid. The “Agreed and Finalized Project Plan” is the version of the Project Plan approved by the Purchaser, in accordance with GCC Clause 19.2. Should the Project Plan conflict with the Contract in any way, the relevant provisions of the Contract, including any amendments, shall prevail.

  • Manufacturing site means the facilities where a Compound is Manufactured by or on behalf of a Party, as such Manufacturing Site may change from time to time in accordance with Section 8.7.

  • Proposed Project SCHEDULE: (edit schedule below as appropriate) Project Event Completion Date Pre-bid Meeting Questions Due Proposals Due Begin Work Programming Phase Permitting Phase Schematic Design Phase Design Development Phase Construction Documents Phase Bidding or Negotiation Phase Construction Administration 1-Year Warranty

  • Project Schedule means a document that, with respect to each Phase of the Project, identifies, coordinates and integrates the anticipated design and construction schedules, the Contracting Authority’s and Owner's responsibilities, government authority reviews and other activities as are necessary for the timely completion of the Work.

  • Development Site means any parcel or lot on which exists or which is intended for building development other than the following:

  • Quantitative fit test or "QNFT" means an assessment of the adequacy of respirator fit by numerically measuring the amount of leakage into the respirator.

  • Phase II Trial means a clinical trial of a Licensed Product on patients, including possibly pharmacokinetic and dose ranging studies, the principal purposes of which are to make a preliminary determination that such Licensed Product is safe for its intended use and to obtain sufficient information about such Licensed Product’s efficacy to permit the design of further clinical trials, and generally consistent with 21 CFR §312.21(b), or its successor regulation, or the equivalent in any foreign country.

  • Qualified project means the construction or expansion of any capital project of the Borrower or any of its Restricted Subsidiaries, the aggregate actual or budgeted capital cost of which (in each case, including capital costs expended by the Borrower or any such Restricted Subsidiaries prior to the construction or expansion of such project) exceeds $50,000,000.

  • Batch means a specific quantity of Product that is intended to have uniform character and quality, within specified limits, and is produced according to a single manufacturing order during the same cycle of manufacture.

  • Phase I Trial means a clinical trial of a Licensed Product in human patients conducted primarily for the purpose of determining the safety, tolerability and preliminary activity of the Licensed Product, including, without limitation, for determining the maximum tolerated dose, or optimal dose. For purposes of this Agreement, a Phase I trial shall specifically exclude a study in healthy volunteers.

  • Phase II Study means a study in humans of the safety, dose ranging or efficacy of a product, as further defined in 21 C.F.R. § 312.21(b) (or the equivalent thereof outside the United States).

  • Development Project means a project for the development of land within a

  • Project Completion means completion of the Redevelopment in accordance with this Agreement to the state where the whole of the Morley Shopping Centre, as so redeveloped, is capable of occupation for its intended purpose;

  • Research facility means buildings and structures, including machinery and equipment, used or to be used primarily for research or experimentation to improve or develop new tangible goods or materials or to improve or develop the production processes thereto.