Orphan Receptor definition

Orphan Receptor means a G Protein Coupled Receptor that is not constitutively active and for which the Endogenous ligand is not publicly known.
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Orphan Receptor means all species of any of (i) the *** *** receptors, and (ii) any orphan receptor discovered by Ligand prior to the expiration of the Ligand Option.
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Orphan Receptor means a GPCR lacking any identified Known Ligand.
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Examples of Orphan Receptor in a sentence

  • The Parties further acknowledge and agree that after the Effective Date, if the Endogenous ligand for any Arena ************** Orphan Receptor is discovered, then such non-orphan receptor shall continue to be treated as an Arena ************** Orphan Receptor for purposes of this Agreement.

  • In the event that Arena does provide such Notice to Fujisawa and Fujisawa does not provide Notice to Arena within such twenty-one (21) day period, Fujisawa shall be deemed to have understood the rights of Arena to exercise its ownership interests in and to such Arena ************** Orphan Receptor, and all data related thereto, whether developed by Arena or Fujisawa.

  • Unless otherwise specified as contemplated by Section 301, the Securities of each series shall be issuable in registered form without coupons.

  • The Parties further acknowledge and agree that in the event that a Third Party wishes to secure rights to any Arena ************** Orphan Receptor, Arena shall provide Notice to Fujisawa informing Fujisawa of such Third Party interest together with documentation evidencing such Third Party interest; Fujisawa shall thereafter have twenty-one (21) days to provide Notice to Arena as to whether Fujisawa shall exercise the provisions of Section 2.6 of this Agreement.

  • In the event that the Arena Antisense Oligonucleotide meets the Cooperative Efficacy Criteria, then the Parties acknowledge and agree that the provisions of Article III shall automatically begin with respect to the Arena ************** Orphan Receptor corresponding to such Arena Antisense Oligonucleotide.

  • EXHIBIT A ------------------------------ ------------------------------- Orphan Receptor Technology U.S. Series No., Patent ------------------------------ ------------------------------- ------------------------------ ------------------------------- *** *** *** *** *** *** ------------------------------ ------------------------------- ----------------- *** Portions of this page have been omitted pursuant to a request for Confidential Treatment and filed separately with the Commission.

  • Upon selection by Fujisawa of the first Arena ************** Orphan Receptor that is the subject of a Success Notice or Initiation Notice, Fujisawa shall, within one (1) month of such Success Notice or one (1) month of such Initiation Notice, provide to Arena Developing Receptor Fee of ******************************************.

  • Upon selection by Fujisawa of the first Arena ************** Orphan Receptor that is the subject of a Success Notice or Initiation Notice, Fujisawa shall, within one (1) month of such Success Notice or one (1) month of such Initiation Notice, provide to Arena Developing Receptor Fee of Five Hundred Thousand Dollars (US$500,000).