NAFLD definition
Examples of NAFLD in a sentence
Field of Use: USE OF THE TECHNOLOGY FOR TREATMENT OF HUMAN DISEASES (INCLUDING IN CLINICAL TRIALS), including but not limited to: cancers, obesity, non- alcoholic steatohepatitis (N▇▇▇), non-alcoholic fatty liver disease (NAFLD).
For these genetic modifiers their biological function and role in the pathology NAFLD remains to be determined.
In the past decade many more studies have enlarged the number of SNPs found in genes related to several altered pathways in NAFLD or that are involved in any of its risk factors and comorbidities.
However, as BMI increases, the intensity of insulin resistance in high ALT NAFLD group becomes stronger, compared with other groups (S1 Fig).
Risk factors for toxicity include: History of adverse drug events; medical comorbidities including renal and liver impairment (e.g. NAFLD) and malignancy; patients at the extremes of weight (BMI <18 or >30 kg/m2), and old age (>80 years).
Expression levels of BSEP, which were found decreased in patients with NAFLD and ▇▇▇▇ (▇▇▇▇▇ et al., 2017; ▇▇▇▇ et al., 2018), or unchanged (▇▇▇▇ et al., 2018a).
For this reason, the investigation of the genetic contribution to the development and progression of NAFLD for this project was explored using a candidate-gene approach.
Fatty liver can be caused by excessive use of alcohol, steatogenic medication, hepatitis virus, autoimmune or hereditary disorders, but when the patient does not have those underlying liver conditions, the fatty liver is diagnosed as NAFLD (11).
The main purpose of this study is to assess the hypothesis that there is a negative association between NAFLD and BMD in the population of the United States.
After controlling for gender/menopausal status, race, age and BMI, the final model showed that high ALT NAFLD has statistically significant negative effect on BMD (beta coefficient: -0.051, 95% CI: -0.081, -0.020) at the overall average BMI level, 27 kg/m2.