Mutagenesis definition

Mutagenesis means the in vitro, in vivo, or in silico introduction of mutations into the DNA sequence encoding an antibody.
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Mutagenesis means the process of producing a change in the genetic material of cells.
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Mutagenesis means mutagenesis is the process by which an organism’s DNA change, resulting in a gene mutation. A mutation is a permanent and heritable change in genetic material, which can result in altered protein function and phenotypic changes;
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Examples of Mutagenesis in a sentence

  • For clarity, the Lead Success Factors for each Lead will include a requirement that the relevant Hit (or antibody that comprises the sequence of a Hit or is derived through Mutagenesis of a Hit) induces a functional response or response via an acceptable Target-specific mechanism.

  • Mutagenesis experiments on the adenosine A2B receptor show that the H7.42E receptor is no longer expressed suggesting a role for this residue in receptor stability and/or expression of this adenosine receptor subtype.

  • Mutagenesis: a word made up of “mutant” and “genesis”, signifying the creation of mutants.

  • Mutagenesis techniques are frequently and successfully applied to study their interaction with ligands, their mechanism of activation and their interaction with G proteins.

  • Nevertheless, we studied all three cysteines as possible sites of 14-3-3 oxidation and generated two 14-3-3 mutants using site-directed mutagenesis (QuikChange Site-directed Mutagenesis Kit, Stratagene).

  • Investigated domain; receptor Domain size (amino acids) Number mutants of Number of single point mutants of selected mutants of interest Mutagenesis method Ref.

  • Mutagenesis to generate Rep-K372A for cloning into pAV2 was performed on this plasmid.

  • Site-directed, Ligase-Independent Mutagenesis 710 (SLIM): a single-tube methodology approaching 100% efficiency in 4 h.

  • Chromosome fragility in dairy cows exposed to dioxins and dioxin-like PCBs. Mutagenesis 2011;26:269-72.

  • Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 490(2), 159-169.

Related to Mutagenesis

  • Carcinogen means a chemical that causes an increased incidence of benign or malignant neoplasms, or a substantial decrease in the latency period between exposure and onset of neoplasms through oral or dermal exposure, or through inhalation exposure when the cancer occurs at nonrespiratory sites in at least one (1) mammalian species or man through epidemiological studies or clinical studies, or both.

  • Aquatic invasive species means any invasive, prohibited,

  • coronavirus means severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2);

  • Anaerobic digester means a liquid manure storage area that is constructed with the intent to capture and combust gas emissions resulting from the digestion of waste by microbes in anaerobic conditions. An anaerobic digester is a LMSA and is required to comply with all requirements applicable to LMSAs. Requirements specific to anaerobic digesters will be noted when applicable.

  • Charcoal lighter material means any combustible material designed to be applied on, incorporated in, added to, or used with charcoal to enhance ignition. “Charcoal Lighter Material” does not include any of the following: (A) electrical starters and probes, (B) metallic cylinders using paper tinder, (C) natural gas,