GPCR definition

GPCR means any G protein-coupled receptor.
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GPCR means a G-protein coupled receptor.
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GPCR means a cell surface receptor protein which, based upon analyses, appears to have seven (7) transmembrane domains and a functional domain for interacting with G proteins;
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Examples of GPCR in a sentence

  • Company is under no obligation to conduct research, development, or commercialization activities relating to any Receptos Technology, Tech Transfer Target, or GPCR; provided that so long as the Success Milestone has not been paid, this Section 4.3 shall not relieve Company from its obligations herein to cooperate with Receptos with respect to achievement of Tech Transfer Success.

  • Receptos possesses certain proprietary G-Protein Coupled Receptor (“GPCR”) structure determination technologies useful in connection with rational development of drugs targeting GPCRs including applications of such technologies to the development of potential drugs targeting the GPCR ***.

  • The site-directed mutations were made based on the following criteria 1) sequence comparison among adenosine receptors and receptors with known structures 2) general GPCR receptor activation domains and 3) comparison of receptor homology models built on two different templates.

  • BMS desires to obtain access to 3DP's Proteomica Database, and to obtain certain licenses under certain of 3DP's proprietary rights and know-how, to conduct research and development with respect to certain GPCR Structures that have applicability in the development and commercialization of diagnostics and pharmaceuticals.

  • LANDLORD: TENANT: BRITANNIA POINTE GRAND LIMITED PARTNERSHIP, a Delaware limited partnership GPCR NEWCO, INC., a Delaware corporation By: HCP-Pointe Grand, Incorporated, a Delaware corporation, its General Partner By: /s/ ▇▇▇▇▇▇▇ ▇▇▇▇▇ By: /s/ ▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇ Name: ▇▇▇▇▇ ▇▇▇▇ Print Name Its: Senior Vice President Its: President 1.

  • The endogenous yeast GPCR gene, Ste2, encoding the a factor receptor was subjected to random mutagenesis to identify amino acids involved in constitutive activity (▇▇▇▇▇▇▇ et al., 2000).

  • Once a Party provides its **************** ********************************************* to the Research Team for evaluation as provided below in Section 4.2(d), neither Party shall be permitted to provide any additional information to either the Research Team or Steering Committee in an effort to establish ******************** of a GPCR by that Party.

  • The Designation of a GPCR as either a Collaboration Receptor (Lilly) or as a Collaboration Receptor (Arena) shall be based solely upon (i) the terms and conditions of this Agreement and (ii) **************************** ******************************************************** provided by a Party under Section 4.2(d).

  • Buyer represents and warrants that it does not intend to use any assays to be acquired or licensed from Seller, including those assays that are part of the GPCR Directed Chemistry Program, in a method to identify and select compounds infringing any of the claims of United States Patent No. 5,401,629, so long as such claim(s) remain outstanding and in effect.

  • Consultant agrees that Consultant will not, without the prior written consent of the Company (which may be withheld in its sole discretion), enter into any agreement to perform (or otherwise perform) services for any entity, other than Company or the Institute, engaged in any activities that are within the field of (i) any modulators of the S1P family or (ii) any small molecule GPCR structure-based drug discovery or development.


More Definitions of GPCR

GPCR means an Endogenous cell-surface receptor defined by having three (3) intracellular loops, three (3) extracellular loops, an amino terminus and a carboxy terminus.
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GPCR means the group prescribed capital requirement, which is the sum of the prescribed capital requirements applicable to the supervised group members in the Insurance Group, as defined in the Group Rules;
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GPCR means a G protein coupled receptor. Portions of this Exhibit were omitted and have been filed separately with the Secretary of the Commission pursuant to the Company's application requesting confidential Investment under Rule 406 of the Securities Act.
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GPCR means any receptor, including but not limited to any G-protein coupled receptor or other protein in a signaling pathway involving a receptor, and includes receptors occurring in nature as well as receptors that have been modified.
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GPCR means a G-protein coupled receptor. 1.21 "GPCR Field" means the discovery, development, supply and commercialization of products or processes that directly bind and/or modulate the function of the twelve GPCRs as set forth in Attachment 1.21, as the same may be modified pursuant to Section 2.4(e). 1.22 "Health Registration" means any and all consents, licenses, authorizations, reimbursement pricing or approvals required by the U.S. Food and Drug Administration or any Ministry of Health for the distribution, sale, manufacture, or testing of a pharmaceutical product, including, without limitation, an IND, NDA or supplemental NDA or other application or supplemental application for a Health Registration. 7 <PAGE> 1.23. "IND" means an Investigational New Drug application, as described by the U.S. Food, Drug and Cosmetics Act of 1938, 21 U.S.C. 301 et seq., as amended, and associated regulations. 1.24. "Inventions" or "Technology" mean all inventions, trade secrets and other information, whether tangible or intangible, whether or not patentable, resulting from work by the parties (either individually or jointly) in the Field during the Research Term. 1.25 "Joint Projects" mean the research projects undertaken by the parties pursuant to the Multi-Project Collaboration Agreement and identified in Attachment 2.2 as "Joint Projects". 1.26. "J-V" means such collaborative relationship as may be established pursuant to Section 3.7 of this Agreement. J-V may or may not be structured as a separate legal entity, such as a corporation, partnership, LLC, or such other form as the Parties may agree. In agreeing on the form of the collaborative relationship, the Parties shall take appropriate account of, among other factors, ease of administration and tax liabilities. 1.27. "Know-how" means the entire right, title and interest in trade secret technology. "P&G Know-how" shall mean the entire right, title and interest in Know-how owned solely or jointly by Procter & ▇▇▇▇▇▇ with a Third Party. "Regeneron Know-how" shall mean the entire right, title and interest in Know-how owned solely or jointly by Regeneron with a Third Party. "Joint Know-how" shall mean the entire right, title and interest in Know-how jointly owned by the Parties pursuant to Section 5.1(b). 1.28. "Lead Compound" means a Research Compound that has been demonstrated to meet Success Criteria as ready to begin regulated safety studies and development of clinical supplies pursuant to Section 3.3 during the Resear...
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Related to GPCR

  • Biomarker means a parameter or characteristic in a patient or Patient Sample, the measurement of which is useful (a) for purposes of selecting appropriate therapies or patient populations or monitoring disease susceptibility, severity or state, or monitoring therapies for such patient and/or (b) for predicting the outcome of a particular treatment of such patient.

  • Collaboration Technology means all Collaboration Patents and Collaboration Know-How.

  • Bioassay means the determination of kinds, quantities or concentrations, and, in some cases, the locations of radioactive material in the human body, whether by direct measurement, in vivo counting, or by analysis and evaluation of materials excreted or removed from the human body. For purposes of these regulations, "radiobioassay" is an equivalent term.

  • Library means an organized collection of resources made accessible to the public for reference or borrowing supported with money derived from taxation.

  • DS Electric generation service that is provided at retail pursuant to the Applicable Legal Authorities under the Company’s retail electric tariffs and under any other agreements or arrangements between the Company and Customers, to any Customer that is not being served by an EGS. Default Allocation Assessment – shall have the meaning ascribed to it under the PJM Agreements. Delivery Period – The delivery period specified in an Appendix C Transaction Confirmation. Delivery Point – Means the applicable zone of the Company as designated by PJM. DS Customer(s) – Retail customers who are provided Default Service pursuant to the terms of this Agreement, the Applicable Legal Authorities and the Company’s retail tariffs.