DOPS definition
Examples of DOPS in a sentence
We found that acute restoration of NE to Dbh -/- mice using DOPS restored cocaine-induced anxiety in the EPM.
We thank Sumitomo Pharmaceuticals (Osaka, Japan) for generous donation of the DOPS needed to maintain our Dbh mouse breeding program.
DOPS + benserazide or saline was administered approximately 5 hours prior to EPM testing, when brain restoration of NE peaks in Dbh -/- mice treated with DOPS.
Pregnant Dbh +/- females were given the AR agonists isoproterenol and phenylephrine (20 µg/ml each) + vitamin C (2 mg/ml) from E9.5 to E14.5, and L-3,4-dihydroxyphenylserine (DOPS; 2 mg/ml + vitamin C 2 mg/ml) from E14.5 to birth in their drinking water to rescue the embryonic lethality associated with the homozygous Dbh -/- mutation.
L-3,4-dihydroxyphenylserine (DOPS) can be converted to NE by the enzyme aromatic amino acid decarboxylase (AADC), thus bypassing the requirement for DBH in the NE synthesis pathway.
This particular experiment does not definitively determine if increased anxiety in the DOPS- Cocaine animals was a result of cocaine’s effect following NE restoration, if NE restoration alone was sufficient to alter anxiety behavior, or if both possibilities exist.
Students will be assessed via a number of different assessments tools, these include professionalism, workplace-based assessments (WBAs), mini-CEXs, CBDs, Student Selected Components, Elective and DOPS.
However, DOPS also tended to decrease percent open arm time in saline treated Dbh -/- mice, complicating the interpretation of these results.
Students will be assessed via a number of different assessments tools, these include professionalism, workplace-based assessments (WBAs), mini-CEXs (mini-clinical Examinations), CBDs (Case Based Discussions), Student Selected Components (T Year only) and DOPS (Direct Observation of Procedures).
Because no interaction was found, and since the Vehicle-Cocaine group showed an equally low level of open arm exploration as the DOPS-cocaine group, the possibility remains that DOPS treatment alone can increase anxiety-like behavior in the elevated plus maze.