Disease progression definition

Disease progression means the process of a disease becoming more severe or spreading from one area of a human body to another area of the human body.
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Disease progression using Defined as [ * ]. modified RECIST criteria Re-treatment Litx(TM)+chemo [ * ] Group Survival All patients will be monitored for survival from the time of randomization [ * ]. Data Safety Monitoring Board [ * ] (DSMB) Criteria of Evaluation [ * ] Statistical Methodology [ * ] 3 STUDY OBJECTIVES Assess the time to progression in patients [ * ]. Demonstrate the safety of Litx(TM) therapy. Assess the survival of patients [ * ].
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Examples of Disease progression in a sentence

  • Disease progression is an anticipated occurrence in oncology drug development and is not an AE unto itself.

  • Prior therapy must have included: ⎯ Anthracycline or bendamustine-containing chemotherapy, and ⎯ Anti-CD20 monoclonal antibody therapy, and ⎯ Ibrutinib or acalabrutinib 103) Relapsed or refractory disease, defined by the following: ⎯ Disease progression after last regimen, or ⎯ Refractory disease is defined failure to achieve a partial response (PR) or CR to the last regimen 104) At least 1 measurable lesion.

  • Disease progression at 6 months All patients that receive trial treatment will be included in the analysis to determine the percentage of patients progressing by RECIST 1.1 criteria at 6 months when maintained on a combination regimen of paricalcitol plus pembrolizumab versus pembrolizumab alone.

  • Disease progression from HIV to AIDS is tracked by CD4+ counts and other co-infections, such as tuberculosis.

  • Topo) chosen prior to randomization Disease progression will be evaluated by the Investigator using RECIST v 1.1 (Appendix B).

  • Events that meet the criteria for serious but are thought to be associated with the progression of the disease under study should be reported as SAEs. NOTE: Disease progression per se should not be reported as an SAE.

  • Disease progression will not be determined by CA19-9, however increases in CA19-9 may warrant the investigator to obtain radiographic assessments.

  • Disease progression and patient response will dictate dose adjustments.