Xyrem Supply Agreement Sample Contracts

AMENDMENT NO. 3 TO XYREM SUPPLY AGREEMENT
Xyrem Supply Agreement • March 27th, 2007 • Jazz Pharmaceuticals Inc • Pharmaceutical preparations

THIS AMENDMENT NO. 3 dated this 21st day of March, 2005 (this “Amendment”) to Xyrem Supply Agreement dated June 30, 2000 by and between Orphan Medical, Inc., a Delaware corporation (“ORPHAN”), and DSM Pharmaceuticals, Inc. (formerly, Catalytica Pharmaceuticals, Inc.), a Delaware corporation (“DSM”):

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ORPHAN MEDICAL, INC. AND CATALYTICA PHARMACEUTICALS, INC. XYREM SUPPLY AGREEMENT
Xyrem Supply Agreement • March 27th, 2007 • Jazz Pharmaceuticals Inc • Pharmaceutical preparations • North Carolina

THIS AGREEMENT (“Agreement”) is made as of this 30th day of June, 2000 by and between ORPHAN MEDICAL, INC., a Minnesota corporation, having its principal offices at 13911 Ridgedale Drive, Minnetonka, Minnesota 55305 (“ORPHAN”) and Catalytica Pharmaceuticals, Inc., a Delaware corporation, having its principal offices at Intersection US 13/NC11 and US 264, Greenville, North Carolina 27834 (“Catalytica”).

AMENDMENT NO. 3 TO XYREM SUPPLY AGREEMENT
Xyrem Supply Agreement • May 24th, 2007 • Jazz Pharmaceuticals Inc • Pharmaceutical preparations

THIS AMENDMENT NO. 3 dated this 21st day of March, 2005 (this “Amendment”) to Xyrem Supply Agreement dated June 30, 2000 by and between Orphan Medical, Inc., a Delaware corporation (“ORPHAN”), and DSM Pharmaceuticals, Inc. (formerly, Catalytica Pharmaceuticals, Inc.), a Delaware corporation (“DSM”):

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