Exhibit 10.4.4 AMENDMENT NO. 4 TO THE MANUFACTURING AGREEMENT This AMENDMENT No. 4 dated as of July 18, 2002 (the "Amendment") to the Manufacturing Agreement dated as of September 18, 1995, as amended (the "Manufacturing Agreement"), by and between...The Manufacturing Agreement • March 11th, 2005 • Regeneron Pharmaceuticals Inc • Pharmaceutical preparations • New York
AMENDMENT NO. 1 TO THE MANUFACTURING AGREEMENTThe Manufacturing Agreement • August 7th, 2015 • Anacor Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
This AMENDMENT NO. 1 (this “Amendment No. 1”) to that certain MANUFACTURING AGREEMENT, dated as of September 30, 2014 (the “Agreement”), is hereby adopted as of August 5, 2015 (the “Amendment Effective Date”) by and between Anacor Pharmaceuticals, Inc. a company with its principal place of business at 1020 East Meadow Circle, Palo Alto, CA 94303 (“COMPANY”) and Hovione FarmaCiencia SA, a company with its principal place of business at Sete Casas, 2674-506 Loures, Portugal (“HOVIONE”). COMPANY and HOVIONE are sometimes referred to herein individually as a “Party” or together as the “Parties”. Capitalized terms used but not defined herein shall have the meanings such terms are given in the Agreement.
AMENDMENT FOUR TO THE MANUFACTURING AGREEMENT BY AND BETWEEN VIVUS AND CHINOINThe Manufacturing Agreement • May 8th, 2007 • Vivus Inc • Pharmaceutical preparations
This Amendment Four (“Amendment Four”), effective as of December 31, 2006 (“Amendment Date”), by and between VIVUS, Inc., having a principal place of business at 1172 Castro Street, Mountain View, CA 94040 United States of America (“VIVUS”), and CHINOIN Pharmaceutical and Chemical Works Private Co. Ltd., having a principal place of business at H-1045, Budapest, To u. 1-5 Hungary (“CHINOIN”) (VIVUS and CHINOIN collectively, the “Parties”), amends (i) that certain Manufacturing Agreement by and between the Parties dated December 20, 1995 (the “Agreement”) and (ii) Amendment One to the Agreement dated December 11, 1997 (“Amendment One”) and (iii) Amendment Two to the Agreement dated December 18, 1998 (“Amendment Two”) and (iv) Amendment Three to the Agreement dated November 21, 2002 (“Amendment Three”)
Exhibit 10.4.5 AMENDMENT NO. 5 TO THE MANUFACTURING AGREEMENT This AMENDMENT No. 5, dated as of January 1, 2005 (this "Amendment"), to the Manufacturing Agreement dated as of September 18, 1995, as amended, (the "Manufacturing Agreement"), by and...The Manufacturing Agreement • March 11th, 2005 • Regeneron Pharmaceuticals Inc • Pharmaceutical preparations • New York
