Strategic Collaboration And Sample Contracts

SECOND AMENDED AND RESTATED STRATEGIC COLLABORATION AND LICENSE AGREEMENT

Strategic Collaboration And • May 8th, 2015 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

• Contract Type
  Strategic Collaboration And
• Filed
  May 8th, 2015
• Company
  Alnylam Pharmaceuticals, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

This Second Amended and Restated Strategic Collaboration and License Agreement (the “Agreement”) is executed this January 8, 2015 (the “Second Restatement Date”), between Isis Pharmaceuticals, Inc., a Delaware corporation having an address at 2855 Gazelle Court, Carlsbad, CA 92010 (“Isis”) and Alnylam Pharmaceuticals, Inc., a Delaware corporation having an address at 300 Third Street, Cambridge, MA 02142 (“Alnylam”). Isis and Alnylam may be referred to herein as the “Parties,” or each individually as a “Party.”