Number Four Agreement Sample Contracts

Amendment Number Four Agreement
Number Four Agreement • January 26th, 2024 • APRINOIA Therapeutics Inc. • Pharmaceutical preparations

This Amendment Agreement (the “Number Four Agreement”) is entered into as indicated below, among National Institutes for Quantum Science and Technology (“QST”), a research institute in Japan, having an address at 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba 263-8555, Japan, APRINOIA Therapeutics Inc. (“APRINOIA JP”), a corporation of Japan, having an address at Shinkawa 1-2-8, Chuo-ku, Tokyo 104-0033, Japan and Suzhou APRINOIA Therapeutics Co., Ltd. (“APRINOIA CN”), a corporation of China, having an address at R503, 5F, Building B2, 218 Xing Hu Rd., Suzhou Industrial Park, Suzhou 215213, China, in consideration of the mutual agreement to make alterations to the Exclusive License Agreement (the “Original Agreement”) executed on October 20th, 2016 by QST and APRINOIA TW, the Amendment Agreement (the “Number One Agreement”) executed on January 11th ,2018, the Amendment Number Two Agreement (the “Number Two Agreement”) executed on June 1st ,2019 and the Amendment Number Three Agreement (the “

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Amendment Number Four AGREEMENT
Number Four Agreement • June 8th, 2020

This is Amendment Number Four to the above-referenced Agreement (AGREEMENT) between the Flood Mitigation Board and the City of Dubuque. The original AGREEMENT was executed on 2/10/14, Amendment Number One on 4/29/15, Amendment Number Two on 6/29/17, and Amendment Number Three on 10/21/2019.

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