Insmed Incorporated Sample Contracts

INSMED INCORPORATED NON-QUALIFIED STOCK OPTION AGREEMENT UNDER THE 2019 INCENTIVE PLAN
Insmed Incorporated • February 25th, 2021 • INSMED Inc • Pharmaceutical preparations • Virginia

THIS AGREEMENT dated this [_____], between INSMED INCORPORATED, a Virginia corporation (the "Company"), and [_____] ("Participant"), is made pursuant and subject to the provisions of the Insmed Incorporated 2019 Incentive Plan, as amended (the "Plan"), a copy of which has been made available to the Participant. All terms used herein that are defined in the Plan have the same meaning given them in the Plan.

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INSMED INCORPORATED RESTRICTED UNIT AWARD AGREEMENT UNDER THE 2019 INCENTIVE PLAN FOR MEMBERS OF THE BOARD OF DIRECTORS
Insmed Incorporated • February 25th, 2021 • INSMED Inc • Pharmaceutical preparations

Pursuant to the Insmed Incorporated 2019 Incentive Plan (the “Plan”) as amended through the date hereof and this Restricted Stock Unit Award Agreement (this “Agreement”), Insmed Incorporated (the “Company”) hereby grants an award of [AMOUNT] restricted stock units (the “Restricted Stock Units” or the “RSU Award”) to the individual named above (the “Grantee”). The RSU Award shall be referred to herein as the “Award.” Subject to the restrictions and conditions set forth herein and in the Plan, the Grantee shall receive the number of Restricted Stock Units specified above.

INSMED INCORPORATED RESTRICTED UNIT AWARD AGREEMENT
Insmed Incorporated • August 3rd, 2017 • INSMED Inc • Pharmaceutical preparations

Pursuant to the Insmed Incorporated 2017 Incentive Plan (the “Plan”) as amended through the date hereof and this Restricted Stock Unit Award Agreement (this “Agreement”), Insmed Incorporated (the “Company”) hereby grants an award of restricted stock units (the “Restricted Stock Units” or the “RSU Award”) to the individual named above (the “Grantee”). The RSU Award shall be referred to herein as the “Award.” Subject to the restrictions and conditions set forth herein and in the Plan, the Grantee shall receive the number of Restricted Stock Units specified above.

INSMED INCORPORATED AND WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee Second Supplemental Indenture Dated as of May 13, 2021 to Indenture Dated as of January 26, 2018 0.75% Convertible Senior Notes due 2028
Insmed Incorporated • May 13th, 2021 • INSMED Inc • Pharmaceutical preparations • New York

SECOND SUPPLEMENTAL INDENTURE dated as of May 13, 2021 (this “Supplemental Indenture”) between Insmed Incorporated, a Virginia corporation, as issuer (the “Company”, as more fully set forth in Section 1.01) and Wells Fargo Bank, National Association, a national banking association, as trustee (the “Trustee”, as more fully set forth in Section 1.01), supplementing the Indenture, dated as of January 26, 2018, between the Company and the Trustee (the “Base Indenture” and the Base Indenture, as amended and supplemented by this Supplemental Indenture, and as it may be further amended or supplemented from time to time with respect to the Notes, the “Indenture”).

INSMED INCORPORATED RESTRICTED UNIT AWARD AGREEMENT UNDER THE 2019 INCENTIVE PLAN FOR U.S. EMPLOYEES
Insmed Incorporated • February 25th, 2021 • INSMED Inc • Pharmaceutical preparations

Pursuant to the Insmed Incorporated 2019 Incentive Plan (the “Plan”) as amended through the date hereof and this Restricted Stock Unit Award Agreement (this “Agreement”), Insmed Incorporated (the “Company”) hereby grants an award of [_____] restricted stock units (the “Restricted Stock Units” or the “RSU Award”) to the individual named above (the “Grantee”). The RSU Award shall be referred to herein as the “Award.” Subject to the restrictions and conditions set forth herein and in the Plan, the Grantee shall receive the number of Restricted Stock Units specified above. All terms used herein that are defined in the Plan have the same meaning given them in the Plan.

INSMED INCORPORATED NONQUALIFIED STOCK OPTION INDUCEMENT AWARD AGREEMENT
Insmed Incorporated • May 4th, 2023 • INSMED Inc • Pharmaceutical preparations • Virginia

THIS AGREEMENT dated this /$GrantDate$/ (this “Agreement”), between INSMED INCORPORATED, a Virginia corporation (the “Company”), and /$ParticipantName$/ (the “Participant”), is an inducement material to Participant’s entry into employment with the Company or a subsidiary of the Company within the meaning of Rule 5635(c)(4) of the NASDAQ Listing Rules (the “Inducement Award Rule”). If and to the extent that this Agreement conflicts or is inconsistent with the terms, conditions and provisions of Participant’s offer letter or employment agreement with the Company or the applicable subsidiary thereof, dated as of /$HireDate$/ (the “Employment Agreement”), the Employment Agreement shall control, and this Agreement shall be deemed to be modified accordingly so long as such modification is consistent with the Inducement Award Rule and applicable law.

INSMED INCORPORATED NONQUALIFIED STOCK OPTION INDUCEMENT AWARD AGREEMENT
Insmed Incorporated • May 4th, 2023 • INSMED Inc • Pharmaceutical preparations • Virginia

THIS AGREEMENT dated this /$GrantDate$/ (this “Agreement”), between INSMED INCORPORATED, a Virginia corporation (the “Company”), and /$ParticipantName$/ (the “Participant”), is an inducement material to Participant’s entry into employment with the Company or a subsidiary of the Company within the meaning of Rule 5635(c)(4) of the NASDAQ Listing Rules (the “Inducement Award Rule”). If and to the extent that this Agreement conflicts or is inconsistent with the terms, conditions and provisions of Participant’s offer letter or employment agreement with the Company or the applicable subsidiary thereof, dated as of /$HireDate$/ (the “Employment Agreement”), the Employment Agreement shall control, and this Agreement shall be deemed to be modified accordingly so long as such modification is consistent with the Inducement Award Rule and applicable law.

INSMED INCORPORATED RESTRICTED UNIT AWARD AGREEMENT UNDER THE 2019 INCENTIVE PLAN FOR U.S. EMPLOYEES
Insmed Incorporated • October 28th, 2021 • INSMED Inc • Pharmaceutical preparations

Pursuant to the Insmed Incorporated 2019 Incentive Plan (the “Plan”) as amended through the date hereof and this Restricted Stock Unit Award Agreement (this “Agreement”), Insmed Incorporated (the “Company”) hereby grants an award of /$AwardsGranted$/ restricted stock units (the “Restricted Stock Units” or the “RSU Award”) to the individual named above (the “Grantee”). The RSU Award shall be referred to herein as the “Award.” Subject to the restrictions and conditions set forth herein and in the Plan, the Grantee shall receive the number of Restricted Stock Units specified above. All terms used herein that are defined in the Plan have the same meaning given them in the Plan.

INSMED INCORPORATED NON-QUALIFIED STOCK OPTION INDUCEMENT AWARD AGREEMENT
Insmed Incorporated • May 28th, 2015 • INSMED Inc • Pharmaceutical preparations • Virginia

THIS AGREEMENT dated this , between INSMED INCORPORATED, a Virginia corporation (the “Company”), and (“Participant”), is made in connection with Participant’s entry into that certain employment with the Company dated as of and is an inducement material to the Participant’s entry into employment within the meaning of Rule 5635(c)(4) of the NASDAQ Listing Rules.

INSMED INCORPORATED RESTRICTED UNIT AWARD AGREEMENT UNDER THE 2013 INCENTIVE PLAN FOR EMPLOYEES
Insmed Incorporated • March 6th, 2014 • Insmed Inc • Pharmaceutical preparations

Pursuant to the Insmed Incorporated 2013 Incentive Plan (the “Plan”) as amended through the date hereof and this Restricted Stock Unit Award Agreement (the “Agreement”), Insmed Incorporated (the “Company”) hereby grants an award of restricted stock units (the “Restricted Stock Units” or the “RSU Award”) to the Grantee named above. The RSU Award shall be referred to herein as the “Award.” Subject to the restrictions and conditions set forth herein and in the Plan, the Grantee shall receive the number of Restricted Stock Units specified above.

INSMED INCORPORATED NON-QUALIFIED STOCK OPTION AGREEMENT UNDER THE 2013 INCENTIVE PLAN
Insmed Incorporated • March 6th, 2014 • Insmed Inc • Pharmaceutical preparations • Virginia

THIS AGREEMENT dated this , between INSMED INCORPORATED, a Virginia corporation (the “Company”), and (“Participant”), is made pursuant and subject to the provisions of the Insmed Incorporated 2013 Incentive Plan, as amended (the “Plan”), a copy of which has been made available to the Participant. All terms used herein that are defined in the Plan have the same meaning given them in the Plan.

SALES AGREEMENT
Insmed Incorporated • February 25th, 2021 • INSMED Inc • Pharmaceutical preparations • New York

Insmed Incorporated, a Virginia corporation (the “Company”), confirms its agreement (this “Agreement”) with SVB Leerink LLC (the “Agent”), as follows:

INSMED INCORPORATED STOCK OPTION AGREEMENT
Insmed Incorporated • June 10th, 2005 • Insmed Inc • Pharmaceutical preparations • Virginia

THIS AGREEMENT dated this day of , between INSMED INCORPORATED, a Virginia corporation (the “Company”), and (“Participant”), is made pursuant and subject to the provisions of the Insmed Incorporated Amended and Restated 2000 Stock Incentive Plan (the “Plan”), a copy of which is attached. All terms used herein that are defined in the Plan have the same meaning given them in the Plan.

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