Confidential Termination and Settlement Agreement and Mutual Sample Contracts

CONFIDENTIAL TERMINATION AND SETTLEMENT AGREEMENT AND MUTUAL RELEASES
Confidential Termination and Settlement Agreement and Mutual • November 7th, 2019 • Lexicon Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

THIS CONFIDENTIAL TERMINATION AND SETTLEMENT AGREEMENT AND MUTUAL RELEASES (“Termination Agreement”) is entered into as of September 10, 2019 and effective as of September 9, 2019 (the “Settlement Date”), by and between Lexicon Pharmaceuticals, Inc. (“Lexicon”), a Delaware corporation, on the one hand, and Sanofi-Aventis Deutschland GmbH (“Sanofi-Aventis”), a limited liability company formed under the laws of Germany, on the other hand. Each of Lexicon and Sanofi-Aventis is a “Party” to this Termination Agreement, and, collectively, they are the “Parties.” All capitalized terms used herein but not otherwise defined herein shall have the meaning ascribed to such terms in the certain Collaboration and License Agreement, dated November 5, 2015, as amended, between Sanofi and Lexicon (the “License Agreement”).

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